SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XL6_B_SPMB3001_1 (INWARD RECTIFIER POTASSIUM CHANNEL)	2w9p	MULTICYSTATIN (Solanum tuberosum)	4 / 5	ALA A 23 TYR A 27 ALA A 71 TYR A 69	None	1.10A	1xl6A-2w9pA: undetectable 1xl6B-2w9pA: undetectable	1xl6A-2w9pA: 13.45 1xl6B-2w9pA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XL6_B_SPMB3001_1 (INWARD RECTIFIER POTASSIUM CHANNEL)	2w9p	MULTICYSTATIN (Solanum tuberosum)	4 / 5	ALA A 71 TYR A 69 ALA A 23 TYR A 27	None	1.06A	1xl6A-2w9pA: undetectable 1xl6B-2w9pA: undetectable	1xl6A-2w9pA: 13.45 1xl6B-2w9pA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WLK_B_SPMB1302_1 (ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10)	2w9p	MULTICYSTATIN (Solanum tuberosum)	4 / 4	ALA A 23 TYR A 27 ALA A 71 TYR A 69	None	1.05A	2wlkA-2w9pA: undetectable 2wlkB-2w9pA: undetectable	2wlkA-2w9pA: 13.45 2wlkB-2w9pA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WLK_B_SPMB1302_1 (ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10)	2w9p	MULTICYSTATIN (Solanum tuberosum)	4 / 4	ALA A 71 TYR A 69 ALA A 23 TYR A 27	None	1.01A	2wlkA-2w9pA: undetectable 2wlkB-2w9pA: undetectable	2wlkA-2w9pA: 13.45 2wlkB-2w9pA: 13.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XL6_B_SPMB3001_1","INWARD RECTIFIER POTASSIUM CHANNEL;INWARD RECTIFIER POTASSIUM CHANNEL","2w9p","MULTICYSTATIN","Solanum tuberosum",4,"ALA A  23;TYR A  27;ALA A  71;TYR A  69","None","1.10A","1xl6A-2w9pA:undetectable;1xl6B-2w9pA:undetectable","1xl6A-2w9pA:13.45;1xl6B-2w9pA:13.45"],["1XL6_B_SPMB3001_1","INWARD RECTIFIER POTASSIUM CHANNEL;INWARD RECTIFIER POTASSIUM CHANNEL","2w9p","MULTICYSTATIN","Solanum tuberosum",4,"ALA A  71;TYR A  69;ALA A  23;TYR A  27","None","1.06A","1xl6A-2w9pA:undetectable;1xl6B-2w9pA:undetectable","1xl6A-2w9pA:13.45;1xl6B-2w9pA:13.45"],["2WLK_B_SPMB1302_1","ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10;ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10","2w9p","MULTICYSTATIN","Solanum tuberosum",4,"ALA A  23;TYR A  27;ALA A  71;TYR A  69","None","1.05A","2wlkA-2w9pA:undetectable;2wlkB-2w9pA:undetectable","2wlkA-2w9pA:13.45;2wlkB-2w9pA:13.45"],["2WLK_B_SPMB1302_1","ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10;ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10","2w9p","MULTICYSTATIN","Solanum tuberosum",4,"ALA A  71;TYR A  69;ALA A  23;TYR A  27","None","1.01A","2wlkA-2w9pA:undetectable;2wlkB-2w9pA:undetectable","2wlkA-2w9pA:13.45;2wlkB-2w9pA:13.45"]]