SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 LYS A 213
LEU A 218
THR A 209
LEU A 215
 None
None
GOL  A1363 (-3.6A)
None
 1.16A 1etb2-2w9xA:
undetectable		 1etb2-2w9xA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		3 / 3 LEU A  66
PHE A 127
ARG A  78
 None
 0.88A 1xdkB-2w9xA:
undetectable		 1xdkB-2w9xA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 8 SER A 294
LEU A 328
PRO A 337
HIS A 336
 None
None
None
GOL  A1362 (-4.5A)
 0.94A 2ddwA-2w9xA:
4.2		 2ddwA-2w9xA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 12 LEU A 244
GLU A 257
GLY A 201
SER A 214
ASP A 150
 None
 1.42A 3ou6D-2w9xA:
undetectable		 3ou6D-2w9xA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 9 SER A 160
THR A 173
THR A 174
ASN A 158
GLY A 155
 None
None
GOL  A1364 (-3.6A)
None
None
 1.34A 3sfuA-2w9xA:
undetectable		 3sfuA-2w9xA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 11 SER A 160
THR A 173
THR A 174
ASN A 158
GLY A 155
 None
None
GOL  A1364 (-3.6A)
None
None
 1.24A 3sfuC-2w9xA:
undetectable		 3sfuC-2w9xA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 12 GLY A 243
GLY A 149
GLU A 146
PHE A 276
LEU A 291
 None
 1.14A 3vywA-2w9xA:
undetectable		 3vywA-2w9xA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 THR A 246
ASN A 247
GLY A 201
ILE A 242
 None
GOL  A1362 ( 4.6A)
None
None
 0.81A 3w9tF-2w9xA:
undetectable		 3w9tF-2w9xA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 12 ILE A 242
GLY A 149
ASP A 150
ASP A 248
ASN A 272
 None
 1.07A 4a81A-2w9xA:
undetectable		 4a81A-2w9xA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 9 ARG A  35
LEU A 244
GLY A 201
PHE A 200
ASN A 205
 None
None
None
GOL  A1363 (-3.8A)
GOL  A1363 ( 4.7A)
 1.40A 4eb4C-2w9xA:
undetectable		 4eb4C-2w9xA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		5 / 11 ASP A 150
VAL A 241
ILE A 242
TYR A 273
ILE A 202
 None
 1.20A 5d75A-2w9xA:
undetectable		 5d75A-2w9xA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.94A 6e43A-2w9xA:
undetectable		 6e43A-2w9xA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.93A 6e43B-2w9xA:
undetectable		 6e43B-2w9xA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.92A 6e43C-2w9xA:
undetectable		 6e43C-2w9xA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2w9x PUTATIVE ACETYL
XYLAN ESTERASE
(Cellvibrio
japonicus) 		4 / 6 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.99A 6e43D-2w9xA:
undetectable		 6e43D-2w9xA:
22.10