SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2w9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 11 VAL A  53
THR A 101
ILE A  25
LEU A  60
PHE A  21
 None
 0.91A 1z11A-2w9yA:
undetectable		 1z11A-2w9yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 11 VAL A  53
THR A 101
ILE A  25
LEU A  60
PHE A  21
 None
 0.89A 1z11B-2w9yA:
undetectable		 1z11B-2w9yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 10 VAL A  53
THR A 101
ILE A  25
LEU A  60
PHE A  21
 None
 0.96A 1z11C-2w9yA:
undetectable		 1z11C-2w9yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 10 VAL A  53
THR A 101
ILE A  25
LEU A  60
PHE A  21
 None
 0.97A 1z11D-2w9yA:
undetectable		 1z11D-2w9yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 VAL A  67
LEU A  97
THR A  94
VAL A  93
VAL A   3
 None
 1.08A 3czvA-2w9yA:
undetectable
3czvB-2w9yA:
undetectable		 3czvA-2w9yA:
21.67
3czvB-2w9yA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 ARG A  74
LEU A  89
VAL A  93
ASP A 135
 None
 1.17A 3ufnA-2w9yA:
undetectable
3ufnB-2w9yA:
undetectable		 3ufnA-2w9yA:
21.77
3ufnB-2w9yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 PHE A  37
VAL A  53
CYH A  46
LEU A  60
SER A  24
 None
 1.48A 4ot2A-2w9yA:
2.8		 4ot2A-2w9yA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 7 PHE A  21
ILE A  25
GLY A  61
MET A  49
 None
 0.92A 4zdzA-2w9yA:
undetectable		 4zdzA-2w9yA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		5 / 12 CYH A  46
PHE A  37
VAL A  53
LEU A  60
SER A  24
 None
 1.48A 6ci6A-2w9yA:
2.9		 6ci6A-2w9yA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 LEU A  64
THR A  95
ARG A  74
PRO A  15
 None
 1.27A 6ew0B-2w9yA:
undetectable		 6ew0B-2w9yA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 LEU A  64
THR A  95
ARG A  74
PRO A  15
 None
 1.27A 6ew0D-2w9yA:
undetectable		 6ew0D-2w9yA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 LEU A  64
THR A  95
ARG A  74
PRO A  15
 None
 1.26A 6ew0H-2w9yA:
undetectable		 6ew0H-2w9yA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE
(Caenorhabditis
elegans) 		4 / 5 LEU A  64
THR A  95
ARG A  74
PRO A  15
 None
 1.27A 6ew0I-2w9yA:
undetectable		 6ew0I-2w9yA:
18.38