SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wa2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 9 ASP A  80
ALA A 103
SER A 129
GLY A  84
GLY A  82
 SAM  A1248 ( 4.9A)
None
None
SAM  A1248 (-3.4A)
SAM  A1248 (-3.3A)
 1.23A 1bcuH-2wa2A:
undetectable		 1bcuH-2wa2A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  86
TRP A  88
LEU A 106
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
None
 0.59A 1eizA-2wa2A:
16.5		 1eizA-2wa2A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  86
TRP A  88
LEU A 106
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
None
 0.63A 1ej0A-2wa2A:
16.3		 1ej0A-2wa2A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		3 / 3 SER A 239
GLU A  11
ASP A 192
 None
 0.87A 2avdB-2wa2A:
9.3		 2avdB-2wa2A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		3 / 3 SER A  57
ASP A 147
CYH A 182
 SAM  A1248 ( 4.7A)
SAM  A1248 (-3.7A)
None
 0.93A 2br4E-2wa2A:
7.1		 2br4E-2wa2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 11 ASN A 176
TRP A 172
ILE A 169
ALA A 141
VAL A 133
 None
None
None
None
SAM  A1248 (-3.4A)
 1.15A 2gl0B-2wa2A:
undetectable
2gl0C-2wa2A:
undetectable		 2gl0B-2wa2A:
20.65
2gl0C-2wa2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 11 TRP A 172
ILE A 169
THR A 143
ALA A 141
VAL A 133
 None
None
None
None
SAM  A1248 (-3.4A)
 1.20A 2gl0B-2wa2A:
undetectable
2gl0C-2wa2A:
undetectable		 2gl0B-2wa2A:
20.65
2gl0C-2wa2A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  86
TRP A  88
LEU A 106
VAL A 133
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
 0.53A 2nyuA-2wa2A:
14.9		 2nyuA-2wa2A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  86
TRP A  88
LEU A 106
VAL A 133
LYS A 184
 SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
None
 0.77A 2nyuA-2wa2A:
14.9		 2nyuA-2wa2A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		7 / 12 GLY A  82
GLY A  86
TRP A  88
LEU A 106
VAL A 133
THR A 134
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.8A)
None
 0.73A 2nyuB-2wa2A:
15.4		 2nyuB-2wa2A:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		7 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
ASP A 147
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.7A)
 0.32A 2oxtA-2wa2A:
34.9		 2oxtA-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		7 / 12 GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
GLU A 112
ASP A 147
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
SAM  A1248 (-3.7A)
 0.51A 2oxtA-2wa2A:
34.9		 2oxtA-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
GLY A  86
TRP A  88
THR A 105
LEU A 106
GLU A 112
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
 0.63A 2oxtB-2wa2A:
34.8		 2oxtB-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
GLY A  86
TRP A  88
THR A 105
LEU A 106
LYS A 184
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
 0.60A 2oxtB-2wa2A:
34.8		 2oxtB-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
GLU A 112
ASP A 147
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
SAM  A1248 (-3.7A)
None
 0.44A 2oxtC-2wa2A:
34.7		 2oxtC-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
ASP A  80
GLY A  82
GLY A  84
THR A 105
LEU A 106
HIS A 111
GLU A 112
ASP A 147
 SAM  A1248 ( 3.7A)
SAM  A1248 ( 4.9A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.7A)
 0.42A 2oxtD-2wa2A:
34.8		 2oxtD-2wa2A:
53.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.38A 2pxcA-2wa2A:
33.1		 2pxcA-2wa2A:
48.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 10 SER A 190
ALA A 159
ASN A 187
ALA A 155
ALA A 156
 None
 1.01A 2r2vC-2wa2A:
undetectable
2r2vF-2wa2A:
undetectable
2r2vG-2wa2A:
undetectable		 2r2vC-2wa2A:
9.20
2r2vF-2wa2A:
9.20
2r2vG-2wa2A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 10 SER A 190
TYR A 189
ALA A 159
ASN A 187
ALA A 156
 None
 1.38A 2r2vC-2wa2A:
undetectable
2r2vF-2wa2A:
undetectable
2r2vG-2wa2A:
undetectable		 2r2vC-2wa2A:
9.20
2r2vF-2wa2A:
9.20
2r2vG-2wa2A:
9.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		12 / 12 GLY A  59
GLY A  82
GLY A  84
SER A  87
TRP A  88
THR A 105
LEU A 106
GLU A 112
ASP A 132
VAL A 133
THR A 134
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.9A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.8A)
SAM  A1248 ( 4.0A)
 0.01A 2wa2A-2wa2A:
43.6		 2wa2A-2wa2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		11 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
GLU A 112
VAL A 133
THR A 134
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
None
SAM  A1248 (-3.4A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.25A 2wa2B-2wa2A:
37.0		 2wa2B-2wa2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 SER A  57
GLY A  59
TRP A  88
THR A 134
ASP A 147
 SAM  A1248 ( 4.7A)
SAM  A1248 ( 3.7A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.7A)
 1.00A 2wa2B-2wa2A:
37.0		 2wa2B-2wa2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		3 / 3 SER A  87
HIS A 111
ASP A 132
 SAM  A1248 (-3.9A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
 0.72A 2wa2B-2wa2A:
37.0		 2wa2B-2wa2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.29A 3eluA-2wa2A:
32.8		 3eluA-2wa2A:
50.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.32A 3elwA-2wa2A:
33.6		 3elwA-2wa2A:
50.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.37A 3embA-2wa2A:
32.9		 3embA-2wa2A:
50.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  59
GLY A  84
TRP A  88
THR A 105
GLU A 112
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
 0.99A 3embA-2wa2A:
32.9		 3embA-2wa2A:
50.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
LEU A 106
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.31A 3gczA-2wa2A:
34.3		 3gczA-2wa2A:
51.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
GLY A  86
ASP A 132
ASP A 147
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.7A)
 0.67A 3ihtA-2wa2A:
8.4		 3ihtA-2wa2A:
23.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.46A 3p97A-2wa2A:
33.5		 3p97A-2wa2A:
49.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.38A 3p97C-2wa2A:
33.4		 3p97C-2wa2A:
49.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  86
TRP A  88
ASP A 132
ASP A 147
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.7A)
 0.65A 4b17A-2wa2A:
10.1		 4b17A-2wa2A:
20.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.46A 4ctjA-2wa2A:
33.4		 4ctjA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
GLU A 112
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.44A 4ctjC-2wa2A:
33.4		 4ctjC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.44A 4ctkA-2wa2A:
33.4		 4ctkA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.38A 4ctkC-2wa2A:
33.1		 4ctkC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 SER A  57
GLY A  59
TRP A  88
ASP A 147
ILE A 148
 SAM  A1248 ( 4.7A)
SAM  A1248 ( 3.7A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.89A 4ctkC-2wa2A:
33.1		 4ctkC-2wa2A:
50.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  84
GLY A  86
THR A 105
LEU A 106
THR A 134
 SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
 0.79A 4n48A-2wa2A:
16.6		 4n48A-2wa2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  84
GLY A  86
THR A 105
LEU A 106
THR A 134
 SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
 0.72A 4n48B-2wa2A:
16.9		 4n48B-2wa2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  84
GLY A  86
THR A 105
LEU A 106
THR A 134
 SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.5A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
 0.75A 4n49A-2wa2A:
16.2		 4n49A-2wa2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
GLY A  86
LEU A 106
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.1A)
None
 0.78A 4uciA-2wa2A:
9.7		 4uciA-2wa2A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
GLY A  86
LEU A 106
LYS A 184
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.1A)
None
 0.76A 4uciB-2wa2A:
9.2		 4uciB-2wa2A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
GLY A  86
LEU A 106
THR A 134
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
 0.65A 4uckA-2wa2A:
9.3		 4uckA-2wa2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  86
TRP A  88
LEU A 106
THR A 134
 SAM  A1248 (-3.3A)
SAM  A1248 (-4.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
 0.93A 4uckA-2wa2A:
9.3		 4uckA-2wa2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  84
GLY A  86
LEU A 106
THR A 134
LYS A 184
 SAM  A1248 (-3.4A)
SAM  A1248 (-4.4A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.8A)
None
 0.96A 4uckB-2wa2A:
9.7		 4uckB-2wa2A:
21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.46A 5e9qA-2wa2A:
33.2		 5e9qA-2wa2A:
48.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.35A 5e9qC-2wa2A:
33.4		 5e9qC-2wa2A:
48.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.43A 5ec8A-2wa2A:
33.2		 5ec8A-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 SER A  57
GLY A  59
TRP A  88
ASP A 147
ILE A 148
 SAM  A1248 ( 4.7A)
SAM  A1248 ( 3.7A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.80A 5ec8A-2wa2A:
33.2		 5ec8A-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.35A 5ec8C-2wa2A:
33.1		 5ec8C-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.45A 5ehgA-2wa2A:
33.3		 5ehgA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		7 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
VAL A 133
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.4A)
 0.85A 5ehgC-2wa2A:
33.2		 5ehgC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.38A 5ehgC-2wa2A:
33.2		 5ehgC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.49A 5ehiA-2wa2A:
33.4		 5ehiA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.34A 5ehiC-2wa2A:
33.6		 5ehiC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.43A 5eifA-2wa2A:
33.5		 5eifA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.32A 5eifC-2wa2A:
33.5		 5eifC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.50A 5eiwA-2wa2A:
33.4		 5eiwA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.39A 5eiwC-2wa2A:
33.1		 5eiwC-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.45A 5ekxA-2wa2A:
33.4		 5ekxA-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
GLU A 112
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.36A 5ekxB-2wa2A:
33.4		 5ekxB-2wa2A:
50.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.41A 5ikmA-2wa2A:
33.1		 5ikmA-2wa2A:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
THR A 105
VAL A 133
THR A 134
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.8A)
 0.71A 5kpcA-2wa2A:
7.9		 5kpcA-2wa2A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 12 GLY A  82
GLY A  84
ASP A 132
VAL A 133
THR A 134
 SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.8A)
 0.49A 5kpcB-2wa2A:
8.2		 5kpcB-2wa2A:
23.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 ( 4.0A)
 0.35A 5kqrA-2wa2A:
32.5		 5kqrA-2wa2A:
50.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.42A 5kqsA-2wa2A:
32.9		 5kqsA-2wa2A:
50.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 ( 4.0A)
 0.33A 5m5bA-2wa2A:
32.8		 5m5bA-2wa2A:
53.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.36A 5njvA-2wa2A:
32.8		 5njvA-2wa2A:
50.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.37A 5njvB-2wa2A:
32.9		 5njvB-2wa2A:
50.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.49A 5njvC-2wa2A:
32.8		 5njvC-2wa2A:
50.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.59A 5njvC-2wa2A:
32.8		 5njvC-2wa2A:
50.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		11 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.36A 5njvD-2wa2A:
33.1		 5njvD-2wa2A:
50.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
HIS A 111
VAL A 133
ILE A 148
LYS A 184
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.4A)
SAM  A1248 ( 4.0A)
None
 0.56A 5vimA-2wa2A:
32.4		 5vimA-2wa2A:
50.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		8 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
HIS A 111
VAL A 133
ILE A 148
LYS A 184
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.4A)
SAM  A1248 ( 4.0A)
None
 0.43A 5vimB-2wa2A:
32.4		 5vimB-2wa2A:
50.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.52A 5wz1A-2wa2A:
32.9		 5wz1A-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 ( 4.0A)
 0.48A 5wz1B-2wa2A:
32.9		 5wz1B-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.52A 5wz1C-2wa2A:
32.8		 5wz1C-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.51A 5wz1D-2wa2A:
32.9		 5wz1D-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.48A 5wz1E-2wa2A:
32.8		 5wz1E-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.51A 5wz1F-2wa2A:
33.0		 5wz1F-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.48A 5wz1G-2wa2A:
32.8		 5wz1G-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
TRP A  88
THR A 105
HIS A 111
GLU A 112
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
None
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.49A 5wz1H-2wa2A:
32.8		 5wz1H-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.39A 5wz2A-2wa2A:
32.7		 5wz2A-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		10 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
ASP A 132
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.6A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.40A 5wz2B-2wa2A:
32.9		 5wz2B-2wa2A:
52.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		9 / 12 GLY A  59
GLY A  82
GLY A  84
TRP A  88
THR A 105
HIS A 111
VAL A 133
ASP A 147
ILE A 148
 SAM  A1248 ( 3.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 (-4.5A)
SAM  A1248 (-3.8A)
SAM  A1248 (-3.4A)
SAM  A1248 (-3.7A)
SAM  A1248 ( 4.0A)
 0.43A 5wz2C-2wa2A:
32.7		 5wz2C-2wa2A:
52.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 7 GLY A 207
GLY A 206
GLY A 226
GLY A  70
GLY A  71
 None
 0.79A 6ag0A-2wa2A:
undetectable		 6ag0A-2wa2A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 2wa2 NON-STRUCTURAL
PROTEIN 5
(Modoc
virus) 		5 / 11 SER A  57
GLY A  82
GLY A  84
LEU A 106
ASP A 132
 SAM  A1248 ( 4.7A)
SAM  A1248 (-3.3A)
SAM  A1248 (-3.4A)
SAM  A1248 (-4.1A)
SAM  A1248 (-3.6A)
 0.81A 6i5zD-2wa2A:
7.7		 6i5zD-2wa2A:
20.98