SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2waa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 6 HIS A  97
ILE A  69
ALA A  54
VAL A  67
 None
ACT  A1344 ( 4.6A)
None
GOL  A1349 (-4.4A)
 0.98A 1hk1A-2waaA:
undetectable		 1hk1A-2waaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 6 ARG A 187
GLY A 211
ASP A 212
TYR A  38
 ACT  A1342 (-4.1A)
ACT  A1345 (-3.6A)
None
None
 1.48A 1kf6M-2waaA:
0.8
1kf6N-2waaA:
undetectable		 1kf6M-2waaA:
20.33
1kf6N-2waaA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 LEU A 202
ASN A 201
GLN A 207
LEU A 259
TYR A 248
 None
 1.07A 3d90B-2waaA:
undetectable		 3d90B-2waaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 LEU A 125
GLU A  96
LEU A  52
LEU A 119
GLY A 121
 None
 0.91A 3g1uA-2waaA:
5.3		 3g1uA-2waaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 LEU A 125
GLU A  96
LEU A  52
LEU A 119
GLY A 121
 None
 0.93A 3g1uC-2waaA:
2.2		 3g1uC-2waaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 GLN A 180
HIS A 263
ARG A  25
HIS A 221
LEU A 138
 None
 1.33A 3njzA-2waaA:
1.4		 3njzA-2waaA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 6 ASN A 262
HIS A 221
PRO A 226
LEU A 136
 None
 0.97A 3oi8A-2waaA:
undetectable		 3oi8A-2waaA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 SER A 231
TYR A 167
LEU A 329
ILE A 336
MET A 337
 None
 1.49A 3qt0A-2waaA:
undetectable		 3qt0A-2waaA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 9 TYR A 252
THR A 271
LEU A 202
GLY A 139
THR A 143
 None
 1.44A 4c9kA-2waaA:
undetectable		 4c9kA-2waaA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 9 TYR A 252
THR A 271
LEU A 202
GLY A 139
THR A 143
 None
 1.45A 4c9kB-2waaA:
undetectable		 4c9kB-2waaA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 8 TYR A 252
THR A 271
LEU A 202
GLY A 139
THR A 143
 None
 1.43A 4c9nA-2waaA:
undetectable		 4c9nA-2waaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 10 ALA A 174
VAL A 179
ARG A 327
ILE A 230
THR A 143
 None
 1.11A 4j14A-2waaA:
undetectable		 4j14A-2waaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 8 ILE A  68
GLU A 100
ILE A  65
LEU A  43
 None
 0.91A 4mj8A-2waaA:
undetectable		 4mj8A-2waaA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 9 TYR A 248
THR A 291
GLY A 289
LEU A 295
VAL A 300
 None
 1.43A 4mjrA-2waaA:
undetectable		 4mjrA-2waaA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 TYR A 248
GLY A 273
ILE A 275
SER A 231
ALA A 232
 None
 1.14A 4qtuD-2waaA:
4.5		 4qtuD-2waaA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 7 LEU A 333
LEU A 228
LEU A 329
ALA A 303
 None
 0.64A 4z90F-2waaA:
undetectable
4z90G-2waaA:
undetectable
4z90H-2waaA:
undetectable
4z90J-2waaA:
undetectable		 4z90F-2waaA:
20.43
4z90G-2waaA:
20.43
4z90H-2waaA:
20.43
4z90J-2waaA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 ALA A 163
GLN A 111
GLY A  37
THR A  35
GLU A 106
 None
 1.14A 5hfjC-2waaA:
undetectable		 5hfjC-2waaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 ALA A 163
GLN A 111
GLY A  37
THR A  35
GLU A 106
 None
 1.17A 5hfjG-2waaA:
2.4		 5hfjG-2waaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 11 ASP A  66
PRO A  74
ARG A 164
GLU A 165
ALA A 152
 None
 1.47A 6bm5A-2waaA:
undetectable		 6bm5A-2waaA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 HIS A 103
PHE A  36
LEU A 136
ARG A 223
GLY A  37
 None
None
None
GOL  A1350 (-4.4A)
None
 1.45A 6brdA-2waaA:
undetectable		 6brdA-2waaA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 8 ILE A 135
VAL A 137
PRO A 226
ALA A 232
THR A 271
 None
 1.39A 6cduD-2waaA:
undetectable
6cduE-2waaA:
undetectable		 6cduD-2waaA:
19.45
6cduE-2waaA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 7 ALA A 232
THR A 271
ILE A 135
VAL A 137
PRO A 226
 None
 1.35A 6cduF-2waaA:
undetectable
6cduJ-2waaA:
undetectable		 6cduF-2waaA:
19.45
6cduJ-2waaA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		5 / 12 LEU A 125
THR A 122
GLU A  96
LEU A  52
LEU A 119
 None
 1.39A 6gbnC-2waaA:
5.8		 6gbnC-2waaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2waa XYLAN ESTERASE,
PUTATIVE, AXE2C
(Cellvibrio
japonicus) 		4 / 6 ILE A 233
LEU A 202
TYR A 248
THR A 253
 None
 1.15A 6nmfN-2waaA:
undetectable
6nmfW-2waaA:
undetectable		 6nmfN-2waaA:
19.62
6nmfW-2waaA:
10.26