SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 2wac CG7008-PA
(Drosophila
melanogaster) 		4 / 8 GLU A 830
ARG A 833
LEU A 879
GLU A 877
 None
 0.99A 1cmaA-2wacA:
undetectable
1cmaB-2wacA:
undetectable		 1cmaA-2wacA:
19.72
1cmaB-2wacA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 2wac CG7008-PA
(Drosophila
melanogaster) 		4 / 8 GLU A 709
TYR A 783
PHE A 760
GLY A 787
 None
 1.14A 2ha4A-2wacA:
undetectable		 2ha4A-2wacA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2wac CG7008-PA
(Drosophila
melanogaster) 		4 / 5 ARG A 796
ALA A 758
TYR A 767
GLN A 759
 None
 1.24A 6f6sA-2wacA:
undetectable
6f6sB-2wacA:
undetectable		 6f6sA-2wacA:
15.82
6f6sB-2wacA:
18.14