SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 TRP A 182
LYS A 213
GLY A 226
ASN A 228
 None
 1.21A 1dedA-2wanA:
28.0		 1dedA-2wanA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 TRP A 182
LYS A 213
TRP A 220
ASN A 228
 None
 1.23A 1dedA-2wanA:
28.0		 1dedA-2wanA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		6 / 12 TYR A 509
ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.80A 1dedB-2wanA:
31.6		 1dedB-2wanA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 4 THR A 352
LEU A 343
LEU A 367
GLN A 358
 None
 1.13A 1fbmA-2wanA:
undetectable		 1fbmA-2wanA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 TYR A 436
PHE A 814
GLY A 482
GLY A 547
LEU A 541
 None
 1.08A 1fe2A-2wanA:
undetectable		 1fe2A-2wanA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 11 VAL A 382
TYR A 378
TYR A 380
PRO A 334
PRO A 570
 None
 1.45A 1klmA-2wanA:
undetectable		 1klmA-2wanA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ALA A 763
HIS A 764
VAL A 767
 None
 0.47A 1lqtB-2wanA:
undetectable		 1lqtB-2wanA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ALA A 763
HIS A 764
VAL A 767
 None
 0.45A 1lquB-2wanA:
undetectable		 1lquB-2wanA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		7 / 12 TYR A 509
HIS A 556
ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
CSX  A 588 ( 4.0A)
None
None
None
None
None
 0.50A 1mxdA-2wanA:
25.5		 1mxdA-2wanA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 GLY A 772
GLY A 716
GLY A 713
TYR A 649
ASN A 549
 None
 0.94A 1n2xB-2wanA:
undetectable		 1n2xB-2wanA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 GLU A 855
ASN A 867
TRP A 888
 None
 1.07A 1r15C-2wanA:
undetectable		 1r15C-2wanA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 GLU A 855
ASN A 867
TRP A 888
 None
 1.06A 1r15D-2wanA:
undetectable		 1r15D-2wanA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 GLU A 855
ASN A 867
TRP A 888
 None
 1.05A 1r15E-2wanA:
undetectable		 1r15E-2wanA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 GLU A 855
ASN A 867
TRP A 888
 None
 1.01A 1r15F-2wanA:
undetectable		 1r15F-2wanA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 GLY A 716
ILE A 838
GLN A 771
VAL A 431
 None
 0.98A 1rs7B-2wanA:
undetectable		 1rs7B-2wanA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 PHE A 699
THR A 916
VAL A 714
ILE A 710
 None
 0.92A 1t87B-2wanA:
undetectable		 1t87B-2wanA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 11 TYR A 554
SER A 636
VAL A 552
PHE A 621
LEU A 648
 None
 1.19A 1uduA-2wanA:
undetectable		 1uduA-2wanA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_B_ADNB501_1
(HYPOTHETICAL PROTEIN
PH0463)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 11 ILE A 568
ASP A 564
PRO A 394
TYR A 514
ASN A 515
 None
 1.42A 1wu8B-2wanA:
0.0
1wu8C-2wanA:
0.0		 1wu8B-2wanA:
13.62
1wu8C-2wanA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 5 SER A 328
VAL A 369
SER A 323
VAL A 321
 None
 1.36A 2j9cA-2wanA:
undetectable
2j9cB-2wanA:
undetectable
2j9cC-2wanA:
undetectable		 2j9cA-2wanA:
8.58
2j9cB-2wanA:
8.58
2j9cC-2wanA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ASP A 803
ARG A 784
ARG A 806
 None
 0.90A 2j9dA-2wanA:
undetectable
2j9dC-2wanA:
undetectable		 2j9dA-2wanA:
8.58
2j9dC-2wanA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 GLY A 778
ARG A 784
TYR A 436
 None
 0.77A 2opxA-2wanA:
undetectable		 2opxA-2wanA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 8 PHE A 699
THR A 916
VAL A 714
ILE A 710
 None
 0.86A 2qbmA-2wanA:
undetectable		 2qbmA-2wanA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.62A 3aicA-2wanA:
2.2		 3aicA-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.58A 3aicA-2wanA:
2.2		 3aicA-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.64A 3aicB-2wanA:
5.3		 3aicB-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.58A 3aicB-2wanA:
5.3		 3aicB-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		6 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
TYR A 509
 None
 0.61A 3aicC-2wanA:
6.1		 3aicC-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		6 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
TYR A 509
 None
 0.58A 3aicC-2wanA:
6.1		 3aicC-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.64A 3aicD-2wanA:
6.1		 3aicD-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.66A 3aicD-2wanA:
6.1		 3aicD-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.63A 3aicE-2wanA:
8.1		 3aicE-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.60A 3aicE-2wanA:
8.1		 3aicE-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.64A 3aicF-2wanA:
4.6		 3aicF-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.60A 3aicF-2wanA:
4.6		 3aicF-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.66A 3aicG-2wanA:
4.5		 3aicG-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.59A 3aicG-2wanA:
4.5		 3aicG-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
ARG A 684
HIS A 735
 None
 0.65A 3aicH-2wanA:
5.5		 3aicH-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.63A 3aicH-2wanA:
5.5		 3aicH-2wanA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 TYR A 614
GLU A 493
ASP A 498
 None
 0.77A 3bxoA-2wanA:
undetectable		 3bxoA-2wanA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 TYR A 614
GLU A 493
ASP A 498
 None
 0.83A 3bxoB-2wanA:
undetectable		 3bxoB-2wanA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 SER A 798
ASP A 442
HIS A 439
SER A 792
TRP A 507
 GOL  A1926 (-2.7A)
None
None
None
None
 1.35A 3dlcA-2wanA:
undetectable		 3dlcA-2wanA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ARG A 756
GLU A 761
ASP A 815
 None
GOL  A1924 (-3.8A)
None
 0.93A 3g2oA-2wanA:
undetectable		 3g2oA-2wanA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 4 PRO A 848
THR A 849
GLY A 702
THR A 701
 None
SO4  A1933 (-4.2A)
None
None
 1.16A 3ib1A-2wanA:
undetectable		 3ib1A-2wanA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ARG A 330
ASP A 605
ASP A 317
 None
 0.79A 3jayA-2wanA:
undetectable		 3jayA-2wanA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 GLU A 492
TYR A 614
PHE A 619
TYR A 554
 None
 1.32A 3ku9B-2wanA:
undetectable		 3ku9B-2wanA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 8 TYR A 210
VAL A 233
GLY A 208
GLY A 237
 None
 0.77A 3n9jB-2wanA:
undetectable		 3n9jB-2wanA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 TYR A 731
ASP A 688
ASP A 703
 None
GOL  A1922 (-2.4A)
None
 0.71A 3ou6B-2wanA:
undetectable		 3ou6B-2wanA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 PRO A 309
ARG A 310
GLY A 363
PRO A 334
 None
 1.24A 3ucbB-2wanA:
undetectable		 3ucbB-2wanA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ASN A 287
ASP A 289
ASN A 299
 None
 0.78A 4agaA-2wanA:
undetectable		 4agaA-2wanA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 HIS A 542
HIS A 423
GLU A 424
ASP A 617
 None
 1.34A 4apjA-2wanA:
undetectable
4apjP-2wanA:
undetectable		 4apjA-2wanA:
21.53
4apjP-2wanA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ARG A 620
THR A 654
TRP A 653
 None
 1.28A 4d7hA-2wanA:
0.0		 4d7hA-2wanA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 LEU A 762
ALA A 763
LEU A 740
PHE A 817
GLY A 778
 GOL  A1924 (-4.3A)
None
None
None
None
 1.04A 4dm8B-2wanA:
undetectable		 4dm8B-2wanA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 GLY A 772
VAL A 431
PRO A 774
ASN A 730
 None
 0.80A 4forA-2wanA:
undetectable		 4forA-2wanA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 LEU A 341
MET A 357
ASP A 325
 None
 0.71A 4j7xB-2wanA:
undetectable		 4j7xB-2wanA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 10 VAL A 331
TYR A 380
SER A 360
GLY A 363
ASP A 393
 None
 1.50A 4mm7A-2wanA:
0.0		 4mm7A-2wanA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 8 THR A 414
HIS A 615
TRP A 610
PHE A 619
 None
 1.33A 4tzcB-2wanA:
0.4
4tzcD-2wanA:
0.8		 4tzcB-2wanA:
7.83
4tzcD-2wanA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 THR A 414
HIS A 615
TRP A 610
PHE A 619
 None
 1.32A 4tzuB-2wanA:
0.6
4tzuC-2wanA:
0.6		 4tzuB-2wanA:
8.20
4tzuC-2wanA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ARG A 620
THR A 654
TRP A 653
 None
 1.25A 4uglA-2wanA:
undetectable		 4uglA-2wanA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 VAL A 891
ILE A 890
LEU A 845
LEU A 881
 None
 0.98A 4xo7A-2wanA:
6.1		 4xo7A-2wanA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 10 VAL A 331
TYR A 380
GLY A 315
SER A 360
GLY A 363
 None
 1.43A 4xpbA-2wanA:
undetectable		 4xpbA-2wanA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 TYR A 521
GLY A 519
GLU A 493
ARG A 530
 None
 1.25A 4zbqA-2wanA:
undetectable		 4zbqA-2wanA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 5 ALA A 522
TYR A 521
HIS A 556
PHE A 494
 None
None
CSX  A 588 ( 4.0A)
None
 1.21A 4ze2A-2wanA:
undetectable		 4ze2A-2wanA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 8 ALA A 158
VAL A 274
PHE A 142
ALA A 136
MET A 133
 None
 1.39A 4zjzB-2wanA:
2.4		 4zjzB-2wanA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 ARG A 620
ASP A 622
GLU A 651
HIS A 735
ASP A 736
 None
 0.34A 5csyB-2wanA:
19.0		 5csyB-2wanA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 6 TYR A 614
GLY A 519
GLU A 518
ASP A 498
 None
 1.30A 5emlA-2wanA:
4.0		 5emlA-2wanA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 ARG A 620
THR A 654
TRP A 653
 None
 1.28A 5g6cA-2wanA:
undetectable		 5g6cA-2wanA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 THR A 722
SER A 717
ASP A 681
 None
 0.58A 5kvaA-2wanA:
undetectable		 5kvaA-2wanA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 THR A 722
SER A 717
ASP A 681
 None
 0.56A 5kvaB-2wanA:
undetectable		 5kvaB-2wanA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 LEU A 648
ILE A 676
GLY A 677
LEU A 627
MET A 632
 None
 0.85A 5nfjA-2wanA:
undetectable		 5nfjA-2wanA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 HIS A 615
GLU A 613
TRP A 419
 None
 1.07A 5odiD-2wanA:
undetectable		 5odiD-2wanA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 HIS A 615
GLU A 613
TRP A 419
 None
 1.04A 5odqD-2wanA:
undetectable		 5odqD-2wanA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 HIS A 615
GLU A 613
TRP A 419
 None
 1.01A 5odrD-2wanA:
undetectable		 5odrD-2wanA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.68A 5qglA-2wanA:
undetectable		 5qglA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.66A 5qgnA-2wanA:
undetectable		 5qgnA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.71A 5qguA-2wanA:
undetectable		 5qguA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.69A 5qgvA-2wanA:
undetectable		 5qgvA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.70A 5qgwA-2wanA:
undetectable		 5qgwA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.69A 5qgxA-2wanA:
undetectable		 5qgxA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.70A 5qh1A-2wanA:
undetectable		 5qh1A-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.70A 5qh4A-2wanA:
undetectable		 5qh4A-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.70A 5qh9A-2wanA:
undetectable		 5qh9A-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.72A 5qhcA-2wanA:
undetectable		 5qhcA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.68A 5qhfA-2wanA:
undetectable		 5qhfA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		3 / 3 VAL A 616
VAL A 548
GLN A 487
 None
 0.68A 5qhgA-2wanA:
undetectable		 5qhgA-2wanA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 HIS A 615
TRP A 610
PHE A 619
THR A 414
 None
 1.29A 5yizG-2wanA:
0.5
5yizY-2wanA:
0.5		 5yizG-2wanA:
7.23
5yizY-2wanA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 HIS A 615
TRP A 610
PHE A 619
THR A 414
 None
 1.37A 5yizk-2wanA:
0.5
5yizt-2wanA:
0.5		 5yizk-2wanA:
7.23
5yizt-2wanA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 THR A 414
HIS A 615
TRP A 610
PHE A 619
 None
 1.28A 5yizk-2wanA:
0.5
5yizt-2wanA:
0.5		 5yizk-2wanA:
7.23
5yizt-2wanA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 HIS A 615
TRP A 610
PHE A 619
THR A 414
 None
 1.27A 5yj0G-2wanA:
0.5
5yj0Y-2wanA:
0.5		 5yj0G-2wanA:
7.23
5yj0Y-2wanA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 7 THR A 414
HIS A 615
TRP A 610
PHE A 619
 None
 1.26A 5yj0k-2wanA:
0.5
5yj0t-2wanA:
0.5		 5yj0k-2wanA:
7.23
5yj0t-2wanA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 8 HIS A 615
TRP A 610
PHE A 619
THR A 414
 None
 1.29A 5yj1G-2wanA:
0.5
5yj1Y-2wanA:
0.5		 5yj1G-2wanA:
8.11
5yj1Y-2wanA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		4 / 8 THR A 414
HIS A 615
TRP A 610
PHE A 619
 None
 1.31A 5yj1k-2wanA:
0.5
5yj1t-2wanA:
0.5		 5yj1k-2wanA:
8.11
5yj1t-2wanA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 TYR A 509
HIS A 556
ASP A 622
HIS A 735
ASP A 736
 None
CSX  A 588 ( 4.0A)
None
None
None
 0.52A 6ag0A-2wanA:
24.3		 6ag0A-2wanA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 LEU A 648
ILE A 676
GLY A 677
ILE A 729
VAL A 552
 None
 0.92A 6emuA-2wanA:
undetectable		 6emuA-2wanA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 LEU A 648
ILE A 676
GLY A 677
ILE A 729
VAL A 552
 None
 0.96A 6emuB-2wanA:
undetectable		 6emuB-2wanA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2wan PULLULANASE
(Bacillus
acidopullulyticu
s) 		5 / 12 LEU A 648
ILE A 676
GLY A 677
ILE A 729
VAL A 552
 None
 0.94A 6emuC-2wanA:
undetectable		 6emuC-2wanA:
11.83