SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2was'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE B1796
GLN B1802
ALA B1878
ILE B1776
 None
 0.70A 2xkwA-2wasB:
undetectable		 2xkwA-2wasB:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 8 ALA B1855
ALA B1859
ILE B1837
GLU B1817
 None
 0.83A 3dtuC-2wasB:
undetectable
3dtuD-2wasB:
undetectable		 3dtuC-2wasB:
12.23
3dtuD-2wasB:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 8 LYS B1821
LEU B1834
TRP B1813
ASP B1772
 None
 0.79A 3n2oC-2wasB:
undetectable
3n2oD-2wasB:
undetectable		 3n2oC-2wasB:
14.70
3n2oD-2wasB:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		5 / 9 ALA B1810
ILE B1776
THR B1792
PHE B1791
GLU B1795
 None
 1.14A 3qelD-2wasB:
undetectable		 3qelD-2wasB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU B1834
ALA B1855
VAL B1864
ILE B1837
 None
 0.86A 3wsjB-2wasB:
undetectable		 3wsjB-2wasB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL B1869
SER B1870
ALA B1880
GLY B1811
 None
 0.92A 5fpdA-2wasB:
undetectable		 5fpdA-2wasB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL B1869
SER B1870
ALA B1880
GLY B1811
 None
 0.91A 5fpdB-2wasB:
undetectable		 5fpdB-2wasB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 2was 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE
(Saccharomyces
cerevisiae) 		5 / 9 ALA B1855
VAL B1819
VAL B1867
SER B1822
GLY B1824
 None
 1.16A 6bklA-2wasB:
undetectable
6bklB-2wasB:
undetectable
6bklC-2wasB:
undetectable
6bklD-2wasB:
undetectable		 6bklA-2wasB:
11.61
6bklB-2wasB:
11.61
6bklC-2wasB:
11.61
6bklD-2wasB:
11.61