SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 7 GLN A2575
LEU A2605
SER A2571
ASN A2573
 None
 1.15A 1ig3A-2wauA:
undetectable
1ig3B-2wauA:
undetectable		 1ig3A-2wauA:
16.20
1ig3B-2wauA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		3 / 3 ASP A2430
GLU A2517
TYR A2413
 None
 0.80A 1wsvA-2wauA:
undetectable		 1wsvA-2wauA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		3 / 3 TYR A2558
PHE A2609
ARG A2523
 None
 1.23A 4g19D-2wauA:
undetectable		 4g19D-2wauA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		4 / 4 LEU A2355
MET A2441
VAL A2356
ASN A2363
 None
 1.33A 5b8iB-2wauA:
undetectable		 5b8iB-2wauA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)
(Plasmodium
falciparum) 		3 / 3 ASP A2380
ASP A2447
ASN A2358
 None
 0.86A 6gngB-2wauA:
undetectable		 6gngB-2wauA:
18.76