SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		4 / 8 ILE C  96
LEU C 101
LEU C 115
LEU C 104
 None
 0.72A 1eupA-2wblC:
undetectable		 1eupA-2wblC:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 ALA C  62
VAL C  12
TRP C 100
 None
 0.89A 1jo3A-2wblC:
undetectable		 1jo3A-2wblC:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 ALA C  62
VAL C  12
TRP C 100
 None
 0.89A 1jo3B-2wblC:
undetectable		 1jo3B-2wblC:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		4 / 4 VAL C 176
LEU C 146
ILE C  96
LEU C 101
 None
 0.96A 2byoA-2wblC:
undetectable		 2byoA-2wblC:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		4 / 6 PHE C 170
LEU C 156
VAL C 116
VAL C  80
 None
 1.16A 2zawA-2wblC:
undetectable		 2zawA-2wblC:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 GLY C  77
TRP C  59
VAL C  10
 None
 0.68A 3n62B-2wblC:
undetectable		 3n62B-2wblC:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 GLY C  77
TRP C  59
VAL C  10
 None
 0.69A 3n65B-2wblC:
undetectable		 3n65B-2wblC:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 GLY C  77
TRP C  59
VAL C  10
 None
 0.67A 3n66B-2wblC:
undetectable		 3n66B-2wblC:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2wbl RAC-LIKE GTP-BINDING
PROTEIN ARAC2
(Arabidopsis
thaliana) 		3 / 3 GLY C  77
TRP C  59
VAL C  10
 None
 0.68A 5vuoB-2wblC:
undetectable		 5vuoB-2wblC:
18.98