SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		5 / 10 THR A 405
PHE A 409
ALA A 408
VAL A 255
TYR A 313
 None
 1.33A 1claA-2wbnA:
undetectable		 1claA-2wbnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		4 / 7 ARG A 278
GLU A 293
ALA A 408
ALA A 404
 None
 1.07A 2ejfA-2wbnA:
undetectable		 2ejfA-2wbnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		3 / 3 SER A 300
ASP A 296
ASP A 306
 None
 0.90A 3iv6A-2wbnA:
undetectable		 3iv6A-2wbnA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		3 / 3 GLU A 354
LEU A 357
ASP A 358
 None
 0.23A 3ko0A-2wbnA:
undetectable		 3ko0A-2wbnA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		3 / 3 GLU A 354
LEU A 357
ASP A 358
 None
 0.13A 3ko0T-2wbnA:
undetectable		 3ko0T-2wbnA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		5 / 10 ILE A 328
ALA A 320
LEU A 274
ILE A 373
ILE A 291
 None
 1.14A 3prsA-2wbnA:
undetectable		 3prsA-2wbnA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		5 / 12 GLY A 264
ALA A 404
ILE A 319
PHE A 409
ILE A 261
 None
 0.84A 4ax8A-2wbnA:
undetectable		 4ax8A-2wbnA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		5 / 12 GLY A 264
ALA A 404
ILE A 319
PHE A 409
ILE A 261
 None
 0.83A 4azvA-2wbnA:
undetectable		 4azvA-2wbnA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		4 / 8 PHE A 377
ILE A 288
PHE A 240
GLY A 353
 None
 0.99A 4fgjA-2wbnA:
undetectable
4fgjB-2wbnA:
undetectable		 4fgjA-2wbnA:
20.63
4fgjB-2wbnA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		4 / 5 LEU A 265
GLY A 264
ILE A 337
LYS A 332
 None
 1.14A 4ma8C-2wbnA:
undetectable		 4ma8C-2wbnA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		5 / 12 ILE A 288
ILE A 363
ASN A 399
GLU A 376
ILE A 373
 None
 1.08A 5lg3E-2wbnA:
undetectable		 5lg3E-2wbnA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		4 / 8 ILE A 373
ILE A 249
ALA A 362
LEU A 243
 None
 0.77A 5og9A-2wbnA:
undetectable		 5og9A-2wbnA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		3 / 3 GLU A 314
TYR A 313
ARG A 278
 None
 0.63A 5uunA-2wbnA:
undetectable		 5uunA-2wbnA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		3 / 3 GLU A 314
TYR A 313
ARG A 278
 None
 0.67A 5uunB-2wbnA:
undetectable		 5uunB-2wbnA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2wbn TERMINASE LARGE
SUBUNIT
(Bacillus
phage
SPP1) 		4 / 5 ALA A 362
TYR A 289
GLN A 244
ILE A 249
 None
 1.40A 6f6sA-2wbnA:
undetectable
6f6sB-2wbnA:
undetectable		 6f6sA-2wbnA:
17.06
6f6sB-2wbnA:
18.13