SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wbv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		5 / 11 PHE A 516
VAL A 411
PHE A 519
GLY A 404
ILE A 377
 None
None
None
None
SIA  A1545 ( 4.3A)
 1.04A 1z11B-2wbvA:
undetectable		 1z11B-2wbvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 7 LEU A 389
PHE A 424
ILE A 387
PHE A 514
 None
 0.93A 2opxA-2wbvA:
undetectable		 2opxA-2wbvA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 5 ILE A 387
THR A 530
PHE A 528
PHE A 418
 None
 1.28A 3em0A-2wbvA:
undetectable		 3em0A-2wbvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 7 GLY A 404
PHE A 528
CYH A 497
PHE A 519
 None
 1.16A 3ko0D-2wbvA:
undetectable
3ko0E-2wbvA:
undetectable		 3ko0D-2wbvA:
18.23
3ko0E-2wbvA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 7 PHE A 402
PHE A 528
CYH A 497
PHE A 519
 None
 1.14A 3ko0D-2wbvA:
undetectable
3ko0E-2wbvA:
undetectable		 3ko0D-2wbvA:
18.23
3ko0E-2wbvA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		5 / 9 PHE A 418
PHE A 528
ILE A 383
THR A 530
PHE A 519
 None
 1.37A 3t3rB-2wbvA:
undetectable		 3t3rB-2wbvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		5 / 9 PHE A 418
PHE A 528
ILE A 383
THR A 530
PHE A 519
 None
 1.35A 3t3rC-2wbvA:
undetectable		 3t3rC-2wbvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 5 PHE A 418
PHE A 528
ILE A 383
THR A 530
 None
 0.74A 4ejjC-2wbvA:
undetectable		 4ejjC-2wbvA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 6 LEU A 482
LEU A 533
ILE A 383
PHE A 402
 None
 1.11A 4y4dA-2wbvA:
undetectable		 4y4dA-2wbvA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		4 / 7 LEU A 512
PHE A 514
SER A 419
ILE A 477
 None
None
SIA  A1545 (-4.4A)
None
 1.06A 5n5dA-2wbvA:
undetectable		 5n5dA-2wbvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 2wbv FIBER PROTEIN
(Canine
mastadenovirus
A) 		5 / 12 LEU A 482
THR A 526
GLY A 525
GLY A 406
ILE A 383
 None
 1.19A 5tuiB-2wbvA:
undetectable		 5tuiB-2wbvA:
18.13