SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wci'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2wci GLUTAREDOXIN-4
(Escherichia
coli) 		4 / 7 LEU A  74
GLN A  73
LEU A  40
PHE A  47
 None
 1.02A 2dysC-2wciA:
undetectable
2dysJ-2wciA:
undetectable		 2dysC-2wciA:
18.63
2dysJ-2wciA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2wci GLUTAREDOXIN-4
(Escherichia
coli) 		4 / 7 LEU A  74
GLN A  73
LEU A  40
PHE A  47
 None
 1.05A 2eimC-2wciA:
undetectable
2eimJ-2wciA:
undetectable		 2eimC-2wciA:
18.63
2eimJ-2wciA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2wci GLUTAREDOXIN-4
(Escherichia
coli) 		4 / 6 LEU A  74
GLN A  73
LEU A  40
PHE A  47
 None
 1.01A 3ag1C-2wciA:
undetectable
3ag1J-2wciA:
undetectable		 3ag1C-2wciA:
18.63
3ag1J-2wciA:
17.04