SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2wcq TNF-ALPHA INDUCER
PROTEIN
(Helicobacter
pylori) 		5 / 10 ALA A  93
LEU A 169
ILE A 117
LEU A 152
ILE A 176
 None
 1.18A 3jw3A-2wcqA:
undetectable		 3jw3A-2wcqA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2wcq TNF-ALPHA INDUCER
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A 155
HIS A 157
VAL A 166
VAL A 170
ILE A 111
 None
 0.93A 5n0sA-2wcqA:
undetectable		 5n0sA-2wcqA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2wcq TNF-ALPHA INDUCER
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A 155
HIS A 157
VAL A 166
VAL A 170
ILE A 111
 None
 0.95A 5n0tA-2wcqA:
undetectable		 5n0tA-2wcqA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2wcq TNF-ALPHA INDUCER
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A 155
HIS A 157
VAL A 166
VAL A 170
ILE A 111
 None
 0.92A 5n0wB-2wcqA:
undetectable		 5n0wB-2wcqA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2wcq TNF-ALPHA INDUCER
PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A 155
HIS A 157
VAL A 166
VAL A 170
ILE A 111
 None
 0.95A 5n4iA-2wcqA:
undetectable		 5n4iA-2wcqA:
15.40