SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wcv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		5 / 12 ILE A  43
MET A  20
VAL A  16
LEU A  17
ALA A 117
 None
 0.89A 1epbA-2wcvA:
undetectable		 1epbA-2wcvA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		6 / 12 PHE A  28
ILE A  57
LEU A  14
VAL A 121
ALA A  45
ILE A  43
 None
 1.25A 1epbB-2wcvA:
undetectable		 1epbB-2wcvA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		5 / 12 VAL A  50
LEU A  53
ALA A  56
ALA A 119
ILE A  26
 None
 1.02A 1fk6A-2wcvA:
undetectable		 1fk6A-2wcvA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		4 / 6 LEU A  54
TYR A  89
ILE A 132
GLY A 124
 None
 0.95A 2du8B-2wcvA:
undetectable		 2du8B-2wcvA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		5 / 12 PHE A 110
LEU A 134
ILE A  26
ILE A 120
PHE A  33
 None
 1.38A 5uanB-2wcvA:
undetectable		 5uanB-2wcvA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		3 / 3 GLU A  62
ASP A  64
PRO A  69
 None
 0.76A 6berA-2wcvA:
undetectable		 6berA-2wcvA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2wcv L-FUCOSE MUTAROTASE
(Escherichia
coli) 		3 / 3 ALA A  18
PHE A 118
GLN A  41
 None
 0.81A 6eceA-2wcvA:
undetectable		 6eceA-2wcvA:
18.15