SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		3 / 3 ASP A 692
ARG A 651
ILE A 663
 None
 0.67A 1a4gB-2wd6A:
undetectable		 1a4gB-2wd6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		4 / 8 GLY A 641
PHE A 646
ILE A 726
GLN A 492
 None
 1.03A 2a8tB-2wd6A:
undetectable		 2a8tB-2wd6A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		4 / 5 PHE A 496
PHE A 747
PHE A 733
VAL A 583
 None
 1.26A 2lh6A-2wd6A:
undetectable		 2lh6A-2wd6A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		5 / 8 ILE A 726
ILE A 674
ILE A 731
ASN A 750
ALA A 753
 None
 1.35A 2nniA-2wd6A:
undetectable		 2nniA-2wd6A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		5 / 12 SER A 688
GLY A 724
TYR A 673
ASN A 645
PHE A 629
 None
 1.33A 3a27A-2wd6A:
undetectable		 3a27A-2wd6A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		4 / 5 PHE A 669
ILE A 731
PHE A 733
PHE A 646
 None
 1.02A 3owxB-2wd6A:
undetectable		 3owxB-2wd6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		3 / 3 ASP A 661
LYS A 660
ASP A 659
 None
 0.42A 4a7tA-2wd6A:
1.0		 4a7tA-2wd6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		3 / 3 GLU A 591
LYS A 559
ASN A 622
 None
 0.92A 4y1dA-2wd6A:
undetectable
4y1dD-2wd6A:
undetectable		 4y1dA-2wd6A:
17.54
4y1dD-2wd6A:
2.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2wd6 AGGLUTININ RECEPTOR
(Streptococcus
gordonii) 		5 / 12 GLY A 577
PHE A 646
ILE A 722
GLY A 671
THR A 727
 None
 1.14A 4ze2A-2wd6A:
undetectable		 4ze2A-2wd6A:
21.51