SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 VAL A 167
ASP A 168
LEU A  97
ARG A 178
GLY A 190
 None
 1.42A 1ia0B-2wd9A:
undetectable		 1ia0B-2wd9A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 GLU A 477
ARG A 461
ASP A 446
THR A 366
 None
 1.14A 1k4tA-2wd9A:
undetectable		 1k4tA-2wd9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 VAL A 488
ALA A 487
HIS A 518
 None
 0.69A 1q23H-2wd9A:
undetectable		 1q23H-2wd9A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 VAL A 488
ALA A 487
HIS A 518
 None
 0.77A 1q23G-2wd9A:
undetectable		 1q23G-2wd9A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 VAL A 488
ALA A 487
HIS A 518
 None
 0.70A 1q23J-2wd9A:
undetectable		 1q23J-2wd9A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLU A 503
TRP A 568
LYS A 141
 None
 1.39A 1qu2A-2wd9A:
undetectable		 1qu2A-2wd9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 GLU A 477
ARG A 461
ASP A 446
THR A 366
 None
 1.25A 1rr8C-2wd9A:
undetectable		 1rr8C-2wd9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 GLU A 477
ARG A 461
ASP A 446
THR A 366
 None
 1.19A 1rrjA-2wd9A:
0.0		 1rrjA-2wd9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 VAL A 167
ASP A 168
LEU A  97
ARG A 178
GLY A 190
 None
 1.42A 1tubB-2wd9A:
undetectable		 1tubB-2wd9A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 LEU A 323
SER A 324
TYR A 326
LEU A 297
 None
 1.11A 1xz1A-2wd9A:
undetectable		 1xz1A-2wd9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 LEU A 323
SER A 324
TYR A 326
LEU A 297
 None
 1.12A 1xz3A-2wd9A:
undetectable		 1xz3A-2wd9A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TRP A 442
GLU A 365
TYR A 426
 None
 0.97A 2a3aA-2wd9A:
undetectable		 2a3aA-2wd9A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 ILE A 412
TRP A 442
GLY A 362
LEU A 270
HIS A 233
 None
None
IBP  A1570 (-3.9A)
None
None
 1.45A 2a58C-2wd9A:
3.1
2a58D-2wd9A:
2.3		 2a58C-2wd9A:
14.24
2a58D-2wd9A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 ASN A 467
TYR A 361
SER A 340
 None
 0.85A 2gvcB-2wd9A:
undetectable		 2gvcB-2wd9A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 MET A 308
LEU A 300
LEU A 319
GLY A 354
 None
 0.91A 2po5B-2wd9A:
undetectable		 2po5B-2wd9A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 ILE A 357
LEU A 300
LEU A 318
ILE A 260
THR A 353
 None
 0.98A 2w9sA-2wd9A:
undetectable		 2w9sA-2wd9A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 11 ILE A 357
LEU A 300
LEU A 318
ILE A 260
THR A 353
 None
 1.00A 2w9sB-2wd9A:
undetectable		 2w9sB-2wd9A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 TYR A 235
ASN A  45
GLY A 211
GLU A 214
 None
 0.97A 2ys6A-2wd9A:
3.2		 2ys6A-2wd9A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY A 310
ILE A 305
LEU A 331
LEU A 355
ILE A 357
 None
 1.34A 3adsB-2wd9A:
undetectable		 3adsB-2wd9A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TRP A 277
VAL A 111
ARG A 148
 None
 0.88A 3b0wA-2wd9A:
undetectable		 3b0wA-2wd9A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 TYR A 390
ASP A 245
HIS A 233
 None
 0.90A 3e23A-2wd9A:
undetectable		 3e23A-2wd9A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ALA A 386
GLY A 454
GLY A 384
MET A 383
VAL A 392
 None
 1.00A 3f8wA-2wd9A:
undetectable		 3f8wA-2wd9A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ALA A 386
GLY A 454
GLY A 384
MET A 383
VAL A 392
 None
 1.00A 3f8wC-2wd9A:
undetectable		 3f8wC-2wd9A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLY A 280
ALA A 281
ASP A 255
GLY A 247
 None
 0.60A 3so9A-2wd9A:
undetectable		 3so9A-2wd9A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ILE A 357
LEU A 300
LEU A 318
ILE A 260
THR A 353
 None
 1.02A 3tq9A-2wd9A:
undetectable		 3tq9A-2wd9A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 PRO A 135
VAL A 158
LEU A  97
ILE A 123
 None
 0.86A 3u5kC-2wd9A:
undetectable		 3u5kC-2wd9A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 ALA A 351
GLY A 354
LEU A 346
LEU A 355
ILE A 357
 None
 1.18A 3wdmC-2wd9A:
1.8		 3wdmC-2wd9A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 LEU A 297
LEU A 318
MET A 308
THR A 353
 None
 1.27A 4do3A-2wd9A:
1.9		 4do3A-2wd9A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 THR A 369
ILE A 412
VAL A 414
GLY A 421
 None
 0.93A 4eq4B-2wd9A:
5.8		 4eq4B-2wd9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 ILE A 260
ILE A 305
THR A 299
VAL A 295
LEU A 318
 None
 1.48A 4kq8A-2wd9A:
undetectable		 4kq8A-2wd9A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 238
ILE A 269
LEU A 270
ALA A 231
THR A 221
 None
 0.92A 4nkvB-2wd9A:
undetectable		 4nkvB-2wd9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 PHE A  46
ALA A 242
THR A 283
LEU A  86
LEU A 124
 None
 1.18A 4qzuC-2wd9A:
undetectable		 4qzuC-2wd9A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ILE A 357
LEU A 300
LEU A 297
MET A 308
 None
 0.87A 4xtaB-2wd9A:
undetectable		 4xtaB-2wd9A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 ILE A 127
ILE A 132
TYR A 235
GLU A 214
 None
 1.20A 4zzcE-2wd9A:
undetectable		 4zzcE-2wd9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 4 VAL A 111
ILE A 138
ASN A 268
VAL A 116
 None
 1.28A 5ajqA-2wd9A:
undetectable		 5ajqA-2wd9A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 267
GLY A 470
GLU A 339
VAL A 337
PHE A 291
 IBP  A1570 (-3.7A)
None
None
IBP  A1570 (-4.6A)
None
 1.27A 5f9zA-2wd9A:
undetectable		 5f9zA-2wd9A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 ILE A 269
THR A 283
TRP A 277
PHE A 133
LEU A  69
 None
 1.32A 5fhzC-2wd9A:
3.4		 5fhzC-2wd9A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 GLY A 280
ALA A 281
ASP A 255
GLY A 247
 None
 0.64A 5kqyB-2wd9A:
undetectable		 5kqyB-2wd9A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLY A 280
ALA A 281
ASP A 255
GLY A 247
 None
 0.62A 5kr1B-2wd9A:
undetectable		 5kr1B-2wd9A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU A 251
GLY A 247
GLU A 275
LEU A 270
LEU A 368
 None
None
None
None
IBP  A1570 ( 4.4A)
 1.17A 5nwvA-2wd9A:
undetectable		 5nwvA-2wd9A:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY A 280
ALA A 281
ASP A 255
GLY A 247
SER A 272
 None
 0.83A 5t2zA-2wd9A:
undetectable		 5t2zA-2wd9A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLY A 250
ASP A 255
ILE A 305
 None
 0.59A 6dgxB-2wd9A:
undetectable		 6dgxB-2wd9A:
10.07