SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 8 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.21A 1jhqA-2wf7A:
undetectable		 1jhqA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.24A 1jhrA-2wf7A:
undetectable		 1jhrA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 8 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.19A 1jhvA-2wf7A:
undetectable		 1jhvA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.20A 1jhyA-2wf7A:
2.3		 1jhyA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.22A 1l4nA-2wf7A:
undetectable		 1l4nA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.21A 1l5kA-2wf7A:
undetectable		 1l5kA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.21A 1l5mA-2wf7A:
undetectable		 1l5mA-2wf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 8 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.83A 1rtsA-2wf7A:
undetectable		 1rtsA-2wf7A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 11 VAL A 158
GLY A 159
ALA A   4
LEU A   6
SER A 181
 None
 1.14A 2bxgA-2wf7A:
2.1		 2bxgA-2wf7A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		3 / 3 ALA A 113
GLY A 174
SER A 181
 None
 0.49A 2ivuA-2wf7A:
undetectable		 2ivuA-2wf7A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 8 VAL A 199
ILE A 166
PHE A   2
MET A   1
 None
 0.82A 2weyB-2wf7A:
undetectable		 2weyB-2wf7A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 LEU A   6
ALA A 161
GLY A 159
PHE A   7
 None
 0.98A 2wq5A-2wf7A:
1.2		 2wq5A-2wf7A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 ALA A 155
VAL A 160
GLY A 159
LEU A   6
ALA A   4
 None
 0.91A 2z0yA-2wf7A:
undetectable		 2z0yA-2wf7A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		3 / 3 ARG A  38
ASP A 170
ASN A  41
 None
MG  A1220 (-2.5A)
None
 0.84A 2zzmA-2wf7A:
undetectable		 2zzmA-2wf7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 ASP A   8
SER A 114
SER A  48
LYS A 145
 ALF  A1219 ( 2.5A)
ALF  A1219 (-2.8A)
None
ALF  A1219 (-2.7A)
 1.14A 3bc9A-2wf7A:
undetectable		 3bc9A-2wf7A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 12 GLY A  46
ALA A 115
LEU A  44
ASP A 170
GLU A  42
 ALF  A1219 ( 3.1A)
G7P  A1221 ( 3.6A)
None
MG  A1220 (-2.5A)
None
 1.02A 3ckkA-2wf7A:
2.8		 3ckkA-2wf7A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 8 TYR A 207
HIS A 206
VAL A 188
GLY A 189
 None
 0.82A 3em0B-2wf7A:
undetectable		 3em0B-2wf7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 9 THR A  16
GLY A  11
GLY A 119
LEU A 122
SER A 114
 None
MG  A1220 ( 4.5A)
None
None
ALF  A1219 (-2.8A)
 1.28A 4kqiA-2wf7A:
undetectable		 4kqiA-2wf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 PRO A 138
SER A  48
GLU A  50
ASP A  58
 None
 1.30A 4uacA-2wf7A:
undetectable		 4uacA-2wf7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		5 / 11 GLY A 119
VAL A  92
LEU A  97
LEU A 100
PHE A 132
 None
 1.00A 4zmeA-2wf7A:
undetectable		 4zmeA-2wf7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 PHE A 151
ILE A 178
GLY A 174
LYS A 145
 None
None
None
ALF  A1219 (-2.7A)
 1.03A 4zxiA-2wf7A:
2.8		 4zxiA-2wf7A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.89A 5h3aA-2wf7A:
undetectable		 5h3aA-2wf7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.85A 5h3aB-2wf7A:
undetectable		 5h3aB-2wf7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 7 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.84A 5x5qC-2wf7A:
undetectable		 5x5qC-2wf7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 8 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.85A 5x5qD-2wf7A:
undetectable		 5x5qD-2wf7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 8 PHE A   7
ILE A  96
GLY A  11
TYR A  19
 None
None
MG  A1220 ( 4.5A)
None
 0.83A 5x5qF-2wf7A:
undetectable		 5x5qF-2wf7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 4 ASP A 170
ILE A 200
PRO A 191
LEU A 194
 MG  A1220 (-2.5A)
None
None
None
 1.15A 6mkeB-2wf7A:
undetectable		 6mkeB-2wf7A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 2wf7 BETA-PHOSPHOGLUCOMUT
ASE
(Lactococcus
lactis) 		4 / 4 ASP A 170
ILE A 200
PRO A 191
LEU A 194
 MG  A1220 (-2.5A)
None
None
None
 1.21A 6mkeA-2wf7A:
undetectable		 6mkeA-2wf7A:
15.21