SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wfb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EPB_A_9CRA165_2 (EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN)	2wfb	PUTATIVE UNCHARACTERIZED PROTEIN ORP (Desulfovibrio gigas)	4 / 7	ALA A 8 PHE A 30 VAL A 32 VAL A 43	None	0.72A	1epbA-2wfbA: undetectable	1epbA-2wfbA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KM8_B_L8PB201_1 (HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2, MITOCHONDRIAL)	2wfb	PUTATIVE UNCHARACTERIZED PROTEIN ORP (Desulfovibrio gigas)	4 / 8	GLN A 61 ASN A 45 ALA A 47 GLN A 49	None None None ACT A1124 (-4.3A)	1.10A	5km8A-2wfbA: undetectable 5km8B-2wfbA: undetectable	5km8A-2wfbA: 24.31 5km8B-2wfbA: 24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_A_RBFA502_1 (RIBOFLAVIN LYASE)	2wfb	PUTATIVE UNCHARACTERIZED PROTEIN ORP (Desulfovibrio gigas)	6 / 12	PHE A 24 ALA A 60 ALA A 87 GLY A 67 GLY A 29 ALA A 27	None	1.28A	5w4zA-2wfbA: undetectable	5w4zA-2wfbA: 22.22