SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		4 / 5 PRO A 332
ILE A 381
GLY A 377
TYR A 336
 None
 1.08A 2jkjD-2wfgA:
undetectable		 2jkjD-2wfgA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		4 / 5 PRO A 332
ILE A 381
GLY A 377
TYR A 336
 None
 1.08A 2jkjF-2wfgA:
undetectable		 2jkjF-2wfgA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		4 / 8 PRO A 399
THR A 425
GLU A 401
PRO A 473
 None
 0.95A 2v32C-2wfgA:
undetectable
2v32D-2wfgA:
undetectable		 2v32C-2wfgA:
24.21
2v32D-2wfgA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		4 / 8 PRO A 473
PRO A 399
THR A 425
GLU A 401
 None
 1.01A 2v41G-2wfgA:
undetectable
2v41H-2wfgA:
undetectable		 2v41G-2wfgA:
24.21
2v41H-2wfgA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		3 / 3 TYR A 336
VAL A 330
THR A 349
 None
 0.77A 2ygnA-2wfgA:
undetectable		 2ygnA-2wfgA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		5 / 8 VAL A 313
GLY A 408
THR A 409
GLU A 528
ALA A 353
 None
ZZB  A1529 ( 4.6A)
None
None
None
 1.47A 3aruA-2wfgA:
undetectable		 3aruA-2wfgA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		5 / 12 THR A 349
THR A 350
TYR A 526
ASN A 356
TYR A 280
 None
 1.35A 5dsgA-2wfgA:
undetectable		 5dsgA-2wfgA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		5 / 12 THR A 349
THR A 350
TYR A 526
ASN A 356
TYR A 280
 None
 1.37A 5dsgB-2wfgA:
undetectable		 5dsgB-2wfgA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 2wfg CYTOSOLIC
LEUCYL-TRNA
SYNTHETASE
(Candida
albicans) 		4 / 5 ASN A 343
TYR A 368
GLY A 367
ASP A 340
 None
 1.26A 6gh9A-2wfgA:
undetectable		 6gh9A-2wfgA:
14.40