SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 1dz9A-2wjfA:
undetectable		 1dz9A-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 5 HIS A   5
HIS A  42
HIS A 136
ASP A 199
 MN  A1246 (-3.4A)
MN  A1247 ( 3.3A)
MN  A1245 ( 3.5A)
MN  A1246 ( 2.8A)
 0.96A 1e9yB-2wjfA:
14.0		 1e9yB-2wjfA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.06A 1t85A-2wjfA:
undetectable		 1t85A-2wjfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.05A 1t87A-2wjfA:
undetectable		 1t87A-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 0.91A 1uyuB-2wjfA:
undetectable		 1uyuB-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.13A 1v7zA-2wjfA:
undetectable		 1v7zA-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.13A 1v7zB-2wjfA:
undetectable		 1v7zB-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.13A 1v7zC-2wjfA:
undetectable		 1v7zC-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.14A 1v7zD-2wjfA:
undetectable		 1v7zD-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.15A 1v7zE-2wjfA:
undetectable		 1v7zE-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.13A 1v7zF-2wjfA:
undetectable		 1v7zF-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 1yrcA-2wjfA:
undetectable		 1yrcA-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.00A 1yrdA-2wjfA:
undetectable		 1yrdA-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 HIS A   7
GLU A  80
HIS A  42
ALA A 135
 MN  A1246 ( 3.3A)
MN  A1246 (-2.4A)
MN  A1247 ( 3.3A)
MN  A1245 ( 4.7A)
 1.01A 2bnnA-2wjfA:
undetectable
2bnnB-2wjfA:
undetectable		 2bnnA-2wjfA:
24.49
2bnnB-2wjfA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.02A 2feuB-2wjfA:
undetectable		 2feuB-2wjfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 TYR A 159
TYR A 104
GLY A 157
THR A 131
 None
 0.89A 2g70A-2wjfA:
undetectable		 2g70A-2wjfA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 TYR A 159
TYR A 104
GLY A 157
THR A 131
 None
 0.96A 2g70B-2wjfA:
undetectable		 2g70B-2wjfA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 ARG A 206
GLY A  15
PRO A  16
 PO4  A1244 (-3.6A)
None
None
 0.71A 2hreD-2wjfA:
undetectable		 2hreD-2wjfA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 9 THR A  40
LEU A 106
VAL A 133
ASP A   3
VAL A 195
 None
 1.21A 2l8mA-2wjfA:
undetectable		 2l8mA-2wjfA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 ASP A 191
VAL A 150
ARG A 151
ILE A 154
 None
 0.89A 2yfbA-2wjfA:
undetectable		 2yfbA-2wjfA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 ASP A 191
VAL A 150
ARG A 151
ILE A 154
 None
 0.91A 2yfbB-2wjfA:
undetectable		 2yfbB-2wjfA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.01A 2zwtA-2wjfA:
undetectable		 2zwtA-2wjfA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.02A 2zwuA-2wjfA:
undetectable		 2zwuA-2wjfA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.14A 3a6jA-2wjfA:
undetectable		 3a6jA-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 7 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.12A 3a6jB-2wjfA:
undetectable		 3a6jB-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.11A 3a6jC-2wjfA:
undetectable		 3a6jC-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.15A 3a6jE-2wjfA:
undetectable		 3a6jE-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 8 GLU A  80
HIS A   7
ASP A 199
HIS A 136
HIS A  42
 MN  A1246 (-2.4A)
MN  A1246 ( 3.3A)
MN  A1246 ( 2.8A)
MN  A1245 ( 3.5A)
MN  A1247 ( 3.3A)
 1.11A 3a6jF-2wjfA:
undetectable		 3a6jF-2wjfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 3fwfA-2wjfA:
undetectable		 3fwfA-2wjfA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 3fwfB-2wjfA:
undetectable		 3fwfB-2wjfA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.02A 3fwjA-2wjfA:
undetectable		 3fwjA-2wjfA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 ALA A  70
ARG A  35
LYS A   0
 None
 1.04A 3kp3B-2wjfA:
undetectable		 3kp3B-2wjfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.01A 3l63A-2wjfA:
undetectable		 3l63A-2wjfA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 LYS A   0
ARG A  35
ASP A 215
 None
 1.33A 3o7wA-2wjfA:
undetectable		 3o7wA-2wjfA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 4 LEU A  91
ILE A 134
TYR A 104
TYR A  83
 None
 1.50A 3vt7A-2wjfA:
undetectable		 3vt7A-2wjfA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.04A 3wrhA-2wjfA:
undetectable		 3wrhA-2wjfA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 3wrjA-2wjfA:
undetectable		 3wrjA-2wjfA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.02A 3wrlA-2wjfA:
undetectable		 3wrlA-2wjfA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.03A 3wrmA-2wjfA:
undetectable		 3wrmA-2wjfA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.02A 3wrmF-2wjfA:
undetectable		 3wrmF-2wjfA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 HIS A   5
HIS A 201
GLU A 138
ASP A 141
 MN  A1246 (-3.4A)
MN  A1247 ( 3.3A)
None
None
 1.37A 4blvA-2wjfA:
undetectable		 4blvA-2wjfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 TYR A 115
VAL A 150
CYH A 158
ILE A 134
 None
 1.27A 4bqtC-2wjfA:
undetectable
4bqtD-2wjfA:
undetectable		 4bqtC-2wjfA:
22.18
4bqtD-2wjfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 11 HIS A   7
ASN A 163
HIS A   5
ARG A 139
GLU A  80
 MN  A1246 ( 3.3A)
None
MN  A1246 (-3.4A)
PO4  A1244 (-2.8A)
MN  A1246 (-2.4A)
 1.20A 4ir0A-2wjfA:
undetectable
4ir0B-2wjfA:
undetectable		 4ir0A-2wjfA:
23.98
4ir0B-2wjfA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 12 HIS A   7
ASN A 163
HIS A   5
ARG A 139
GLU A  80
 MN  A1246 ( 3.3A)
None
MN  A1246 (-3.4A)
PO4  A1244 (-2.8A)
MN  A1246 (-2.4A)
 1.20A 4jd1A-2wjfA:
undetectable
4jd1B-2wjfA:
undetectable		 4jd1A-2wjfA:
23.98
4jd1B-2wjfA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 0.95A 4l4aA-2wjfA:
undetectable		 4l4aA-2wjfA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 7 THR A  40
LEU A 106
VAL A 133
ASP A   3
 None
 1.05A 4l4gA-2wjfA:
undetectable		 4l4gA-2wjfA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 LEU A 122
HIS A 136
TYR A  82
GLU A 108
 None
MN  A1245 ( 3.5A)
None
MN  A1245 ( 2.6A)
 1.14A 4pahA-2wjfA:
undetectable		 4pahA-2wjfA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 5 VAL A  12
ASP A  13
PHE A  10
GLY A  15
 None
 1.23A 4xp6A-2wjfA:
undetectable		 4xp6A-2wjfA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 ASP A 199
HIS A   7
HIS A 201
HIS A 136
 MN  A1246 ( 2.8A)
MN  A1246 ( 3.3A)
MN  A1247 ( 3.3A)
MN  A1245 ( 3.5A)
 0.83A 5ncdA-2wjfA:
2.2
5ncdD-2wjfA:
5.5		 5ncdA-2wjfA:
22.34
5ncdD-2wjfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 ASP A 199
HIS A   7
HIS A 201
HIS A 136
 MN  A1246 ( 2.8A)
MN  A1246 ( 3.3A)
MN  A1247 ( 3.3A)
MN  A1245 ( 3.5A)
 0.88A 5ncdB-2wjfA:
5.3
5ncdC-2wjfA:
2.2		 5ncdB-2wjfA:
22.34
5ncdC-2wjfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 8 ASP A 199
HIS A   7
HIS A 201
HIS A 136
 MN  A1246 ( 2.8A)
MN  A1246 ( 3.3A)
MN  A1247 ( 3.3A)
MN  A1245 ( 3.5A)
 0.93A 5nekB-2wjfA:
5.4		 5nekB-2wjfA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		4 / 6 ASP A 199
HIS A   7
HIS A 201
HIS A 136
 MN  A1246 ( 2.8A)
MN  A1246 ( 3.3A)
MN  A1247 ( 3.3A)
MN  A1245 ( 3.5A)
 0.81A 5nelA-2wjfA:
5.2
5nelD-2wjfA:
5.4		 5nelA-2wjfA:
22.34
5nelD-2wjfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		5 / 6 HIS A 136
HIS A   7
HIS A 201
LEU A 106
HIS A   5
 MN  A1245 ( 3.5A)
MN  A1246 ( 3.3A)
MN  A1247 ( 3.3A)
None
MN  A1246 (-3.4A)
 1.23A 5nelB-2wjfA:
5.1
5nelC-2wjfA:
5.3		 5nelB-2wjfA:
22.34
5nelC-2wjfA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 HIS A 201
ASP A  14
HIS A  42
 MN  A1247 ( 3.3A)
MN  A1247 (-2.1A)
MN  A1247 ( 3.3A)
 0.63A 5oexA-2wjfA:
undetectable		 5oexA-2wjfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 HIS A 201
ASP A  14
HIS A  42
 MN  A1247 ( 3.3A)
MN  A1247 (-2.1A)
MN  A1247 ( 3.3A)
 0.58A 5oexB-2wjfA:
undetectable		 5oexB-2wjfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 HIS A 201
ASP A  14
HIS A  42
 MN  A1247 ( 3.3A)
MN  A1247 (-2.1A)
MN  A1247 ( 3.3A)
 0.56A 5oexC-2wjfA:
undetectable		 5oexC-2wjfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 HIS A 201
ASP A  14
HIS A  42
 MN  A1247 ( 3.3A)
MN  A1247 (-2.1A)
MN  A1247 ( 3.3A)
 0.55A 5oexD-2wjfA:
undetectable		 5oexD-2wjfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 2wjf TYROSINE-PROTEIN
PHOSPHATASE CPSB
(Streptococcus
pneumoniae) 		3 / 3 HIS A   5
SER A 198
ARG A 206
 MN  A1246 (-3.4A)
None
PO4  A1244 (-3.6A)
 0.99A 5u63A-2wjfA:
undetectable		 5u63A-2wjfA:
22.40