SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 6 ALA A 114
ILE A  19
LEU A 144
ALA A 158
 None
 0.63A 3r9sA-2wjgA:
2.2		 3r9sA-2wjgA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 6 ALA A 114
ILE A  19
LEU A 144
ALA A 158
 None
 0.68A 3r9sC-2wjgA:
undetectable		 3r9sC-2wjgA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  98
ASN A  87
GLN A 103
LEU A 104
 None
 1.16A 4nc3A-2wjgA:
undetectable		 4nc3A-2wjgA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  98
ASN A  87
LEU A 104
GLU A 106
 None
 1.03A 4nc3A-2wjgA:
undetectable		 4nc3A-2wjgA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 7 VAL A  86
ILE A  88
VAL A 142
ALA A 114
 None
 0.76A 5ospA-2wjgA:
undetectable		 5ospA-2wjgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 2wjg FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG
(Methanocaldococc
us
jannaschii) 		3 / 3 MET A 107
GLU A  70
ARG A  74
 None
 0.84A 5tjyA-2wjgA:
7.1		 5tjyA-2wjgA:
19.76