SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wlb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 2wlb ELECTRON TRANSFER
PROTEIN 1,
MITOCHONDRIAL
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A 606
GLU A 534
ILE A 533
 None
 0.46A 3czhA-2wlbA:
undetectable		 3czhA-2wlbA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2wlb ELECTRON TRANSFER
PROTEIN 1,
MITOCHONDRIAL
(Schizosaccharomy
ces
pombe) 		4 / 8 ILE A 617
GLY A 601
LEU A 588
LEU A 594
 None
 0.58A 5hs1A-2wlbA:
undetectable		 5hs1A-2wlbA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 2wlb ELECTRON TRANSFER
PROTEIN 1,
MITOCHONDRIAL
(Schizosaccharomy
ces
pombe) 		4 / 8 GLY A 558
GLY A 601
LEU A 542
GLU A 553
 FES  A 619 (-4.1A)
None
None
None
 0.84A 6mdqA-2wlbA:
undetectable		 6mdqA-2wlbA:
20.00