SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.87A 1gtnC-2wlpA:
undetectable
1gtnD-2wlpA:
undetectable		 1gtnC-2wlpA:
15.12
1gtnD-2wlpA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 6 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.87A 1gtnD-2wlpA:
undetectable
1gtnE-2wlpA:
undetectable		 1gtnD-2wlpA:
15.12
1gtnE-2wlpA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.88A 1gtnF-2wlpA:
undetectable
1gtnG-2wlpA:
undetectable		 1gtnF-2wlpA:
15.12
1gtnG-2wlpA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.90A 1gtnJ-2wlpA:
undetectable
1gtnK-2wlpA:
undetectable		 1gtnJ-2wlpA:
15.12
1gtnK-2wlpA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		3 / 3 TYR A 251
THR A 253
THR A 126
 None
 0.83A 5aoxB-2wlpA:
undetectable		 5aoxB-2wlpA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		3 / 3 TYR A 251
THR A 253
THR A 126
 None
 0.81A 5aoxE-2wlpA:
undetectable		 5aoxE-2wlpA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 2wlp COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 9 ILE A 256
TYR A 254
LEU A  77
GLU A  81
GLY A 110
 None
 1.27A 5ifuB-2wlpA:
undetectable		 5ifuB-2wlpA:
18.24