SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 5 LEU B  14
THR B  18
THR B  47
HIS B  11
 None
 1.20A 2zj0B-2wlvB:
undetectable		 2zj0B-2wlvB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 5 LEU B  14
THR B  18
THR B  47
HIS B  11
 None
 1.17A 2zj0C-2wlvB:
undetectable		 2zj0C-2wlvB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 5 LEU B  14
THR B  18
THR B  47
HIS B  11
 None
 1.14A 3ce6B-2wlvB:
undetectable		 3ce6B-2wlvB:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 6 THR B  47
GLY B 126
ARG B  95
ILE B 102
 None
 1.03A 4ac9C-2wlvB:
undetectable		 4ac9C-2wlvB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 6 THR B  47
GLY B 126
ARG B  95
ILE B 102
 None
 1.04A 4acaC-2wlvB:
undetectable		 4acaC-2wlvB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		4 / 6 ASP B  80
GLU B  78
ILE B 133
PRO B  97
 None
 0.97A 4xi3C-2wlvB:
undetectable		 4xi3C-2wlvB:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 2wlv GAG POLYPROTEIN
(Human
immunodeficiency
virus
2) 		3 / 3 GLY B 104
ASN B  52
ARG B  69
 None
 0.66A 5w7bD-2wlvB:
undetectable		 5w7bD-2wlvB:
16.67