SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		4 / 6 LEU A  17
LEU A  48
LEU A  81
LEU A  82
 None
 0.97A 2ab2A-2wm8A:
undetectable		 2ab2A-2wm8A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		4 / 5 LEU A  17
LEU A  48
LEU A  81
LEU A  82
 None
 0.99A 2ab2B-2wm8A:
undetectable		 2ab2B-2wm8A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 SER A  33
ASP A  40
ASP A  45
 EDO  A1163 (-4.6A)
None
None
 0.73A 2plwA-2wm8A:
3.4		 2plwA-2wm8A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		5 / 12 PHE A 105
VAL A 132
LEU A 151
ALA A   9
PHE A  11
 None
 1.47A 3apxA-2wm8A:
undetectable		 3apxA-2wm8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		5 / 12 LEU A   8
VAL A 137
GLY A 136
ILE A 102
LEU A 108
 None
 0.85A 3ijdA-2wm8A:
undetectable		 3ijdA-2wm8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		5 / 12 LEU A   8
VAL A 137
GLY A 136
ILE A 102
LEU A 108
 None
 0.86A 3ijdB-2wm8A:
undetectable		 3ijdB-2wm8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		4 / 6 ASP A 123
THR A 138
THR A  16
PHE A  11
 None
 0.94A 4acbC-2wm8A:
2.5		 4acbC-2wm8A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.70A 5qglA-2wm8A:
undetectable		 5qglA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.65A 5qguA-2wm8A:
undetectable		 5qguA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.67A 5qgvA-2wm8A:
undetectable		 5qgvA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.65A 5qgwA-2wm8A:
undetectable		 5qgwA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.66A 5qgxA-2wm8A:
undetectable		 5qgxA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.67A 5qgyA-2wm8A:
undetectable		 5qgyA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.66A 5qgzA-2wm8A:
undetectable		 5qgzA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.65A 5qh0A-2wm8A:
undetectable		 5qh0A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.67A 5qh1A-2wm8A:
undetectable		 5qh1A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.65A 5qh2A-2wm8A:
undetectable		 5qh2A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.67A 5qh3A-2wm8A:
undetectable		 5qh3A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.69A 5qh4A-2wm8A:
undetectable		 5qh4A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.68A 5qh6A-2wm8A:
undetectable		 5qh6A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.68A 5qh9A-2wm8A:
undetectable		 5qh9A-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.61A 5qhaA-2wm8A:
undetectable		 5qhaA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.68A 5qhcA-2wm8A:
undetectable		 5qhcA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.65A 5qheA-2wm8A:
undetectable		 5qheA-2wm8A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wm8 MAGNESIUM-DEPENDENT
PHOSPHATASE 1
(Homo
sapiens) 		3 / 3 VAL A  46
VAL A  38
GLN A  80
 None
 0.67A 5qhfA-2wm8A:
undetectable		 5qhfA-2wm8A:
24.55