SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		4 / 6 ILE A 787
ARG A 786
PRO A 699
SER A 702
 None
 1.48A 2qd3B-2wmmA:
undetectable		 2qd3B-2wmmA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		5 / 12 TYR A 690
ASP A 746
PHE A 778
ILE A 737
PHE A 744
 None
 1.31A 4drhA-2wmmA:
undetectable		 4drhA-2wmmA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		5 / 12 TYR A 690
ASP A 746
PHE A 778
ILE A 737
PHE A 744
 None
 1.30A 4drhD-2wmmA:
undetectable		 4drhD-2wmmA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		5 / 11 LEU A 677
VAL A 714
LEU A 734
HIS A 723
LEU A 724
 None
 1.16A 4p65B-2wmmA:
undetectable
4p65D-2wmmA:
undetectable
4p65G-2wmmA:
undetectable
4p65H-2wmmA:
undetectable		 4p65B-2wmmA:
11.18
4p65D-2wmmA:
11.18
4p65G-2wmmA:
9.02
4p65H-2wmmA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		5 / 11 TYR A 690
ASP A 746
PHE A 778
ILE A 737
PHE A 744
 None
 1.40A 5hwcA-2wmmA:
undetectable		 5hwcA-2wmmA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 2wmm CHROMOSOME PARTITION
PROTEIN MUKB
(Escherichia
coli) 		5 / 10 TYR A 690
ASP A 746
PHE A 778
ILE A 737
PHE A 744
 None
 1.49A 6mkeD-2wmmA:
undetectable		 6mkeD-2wmmA:
27.56