SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 7 PHE A 358
LEU A 375
TYR A 354
LYS A 349
 None
 1.20A 1rmtB-2wmoA:
undetectable		 1rmtB-2wmoA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 LEU A 339
GLY A 341
GLU A 320
CYH A 386
 None
 1.19A 3aiaA-2wmoA:
undetectable
3aiaB-2wmoA:
undetectable		 3aiaA-2wmoA:
18.93
3aiaB-2wmoA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 6 PHE A 160
GLY A 162
ALA A 223
LEU A 218
 None
 0.94A 3bgdA-2wmoA:
undetectable		 3bgdA-2wmoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLN A 189
GLU A 178
THR A 154
HIS A 229
 None
 1.39A 3glqB-2wmoA:
undetectable		 3glqB-2wmoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLN A 189
GLU A 178
THR A 154
HIS A 229
 None
 1.43A 3n58A-2wmoA:
undetectable		 3n58A-2wmoA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 173
GLY A 171
TYR A 174
GLU A 169
 None
 1.20A 3w9tA-2wmoA:
undetectable		 3w9tA-2wmoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 173
GLY A 171
TYR A 174
GLU A 169
 None
 1.20A 3w9tC-2wmoA:
undetectable		 3w9tC-2wmoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 173
GLY A 171
TYR A 174
GLU A 169
 None
 1.20A 3w9tD-2wmoA:
undetectable		 3w9tD-2wmoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 173
GLY A 171
TYR A 174
GLU A 169
 None
 1.20A 3w9tG-2wmoA:
undetectable		 3w9tG-2wmoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 6 TYR A 155
HIS A 229
VAL A 158
PHE A 287
 None
 0.77A 4a97E-2wmoA:
5.0		 4a97E-2wmoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 7 TYR A 155
HIS A 229
VAL A 158
PHE A 287
 None
 0.84A 4a97H-2wmoA:
1.3		 4a97H-2wmoA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 7 VAL A  60
ILE A  61
LEU A  87
LEU A  91
 None
 1.04A 4l1wA-2wmoA:
undetectable		 4l1wA-2wmoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 8 LEU A 335
MET A 408
GLN A 405
LYS A 409
 None
 1.04A 4umjA-2wmoA:
3.5		 4umjA-2wmoA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 6 LYS A 180
PRO A 179
LEU A  27
GLU A 102
 None
 1.37A 4z4cA-2wmoA:
undetectable		 4z4cA-2wmoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.08A 5hm8A-2wmoA:
undetectable		 5hm8A-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.09A 5hm8B-2wmoA:
undetectable		 5hm8B-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.08A 5hm8C-2wmoA:
undetectable		 5hm8C-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.08A 5hm8D-2wmoA:
undetectable		 5hm8D-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.09A 5hm8E-2wmoA:
undetectable		 5hm8E-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.08A 5hm8F-2wmoA:
undetectable		 5hm8F-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.12A 5hm8G-2wmoA:
undetectable		 5hm8G-2wmoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9
(Homo
sapiens) 		4 / 5 GLU A 143
THR A 142
GLU A 105
LEU A 134
 None
 1.09A 5hm8H-2wmoA:
undetectable		 5hm8H-2wmoA:
23.05