SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		3 / 3 THR B 243
PRO B 245
THR B 244
 None
 0.86A 1a7yB-2wmpB:
undetectable		 1a7yB-2wmpB:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		3 / 3 LEU B 287
PHE B 237
ARG B 198
 None
 0.88A 1xdkB-2wmpB:
undetectable		 1xdkB-2wmpB:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		4 / 6 TYR B 220
GLY B 290
SER B 266
THR B 288
 None
 1.08A 3tj7A-2wmpB:
undetectable
3tj7B-2wmpB:
undetectable		 3tj7A-2wmpB:
20.53
3tj7B-2wmpB:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		4 / 6 TYR B 220
GLY B 290
SER B 266
THR B 288
 None
 1.06A 3tj7C-2wmpB:
undetectable
3tj7D-2wmpB:
undetectable		 3tj7C-2wmpB:
20.53
3tj7D-2wmpB:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		4 / 6 SER B 266
THR B 288
TYR B 220
GLY B 290
 None
 1.08A 3tj7C-2wmpB:
undetectable
3tj7D-2wmpB:
undetectable		 3tj7C-2wmpB:
20.53
3tj7D-2wmpB:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 2wmp PAPG PROTEIN
(Escherichia
coli) 		5 / 12 GLU B 296
GLY B 295
LEU B 293
SER B 263
ILE B 264
 None
 1.03A 5dpdA-2wmpB:
undetectable		 5dpdA-2wmpB:
11.91