SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		4 / 5 ALA A  57
LEU A 135
GLY A  23
THR A  70
 None
 0.77A 3dl9A-2wmyA:
undetectable		 3dl9A-2wmyA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		4 / 6 GLN A 133
LEU A 135
GLU A 136
LEU A  26
 None
 0.88A 3h5gA-2wmyA:
undetectable
3h5gC-2wmyA:
undetectable		 3h5gA-2wmyA:
12.67
3h5gC-2wmyA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		4 / 6 LEU A  26
GLN A 133
LEU A 135
GLU A 136
 None
 1.05A 3h5gB-2wmyA:
undetectable
3h5gC-2wmyA:
undetectable		 3h5gB-2wmyA:
12.67
3h5gC-2wmyA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		5 / 9 ILE A   9
LEU A  27
ILE A  12
PHE A 108
GLY A 109
 None
 1.17A 3sj4X-2wmyA:
undetectable		 3sj4X-2wmyA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		4 / 8 LEU A  84
THR A 105
ARG A 102
LEU A 107
 None
 1.21A 4qknA-2wmyA:
undetectable		 4qknA-2wmyA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2wmy PUTATIVE ACID
PHOSPHATASE WZB
(Escherichia
coli) 		5 / 12 ILE A  12
GLY A  40
GLY A  42
SER A  74
HIS A  90
 None
 1.02A 5twjA-2wmyA:
2.3		 5twjA-2wmyA:
18.45