SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wnk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 2wnk SPOROZOITE-SPECIFIC
SAG PROTEIN
(Toxoplasma
gondii) 		5 / 12 TYR A  39
LEU A  84
THR A  85
VAL A  86
LEU A  59
 None
 1.10A 4g1bD-2wnkA:
undetectable		 4g1bD-2wnkA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2wnk SPOROZOITE-SPECIFIC
SAG PROTEIN
(Toxoplasma
gondii) 		5 / 9 LEU A  63
VAL A  96
SER A  95
VAL A 127
LEU A 126
 None
 1.22A 4qd3A-2wnkA:
undetectable		 4qd3A-2wnkA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 2wnk SPOROZOITE-SPECIFIC
SAG PROTEIN
(Toxoplasma
gondii) 		4 / 7 GLY A 201
GLY A 159
SER A 137
LEU A 143
 None
 0.82A 5izfA-2wnkA:
undetectable		 5izfA-2wnkA:
19.06