SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2wno TUMOR NECROSIS
FACTOR-INDUCIBLE
GENE 6 PROTEIN
(Homo
sapiens) 		3 / 3 LYS A 243
VAL A 245
HIS A 174
 None
 0.33A 3tj7A-2wnoA:
undetectable		 3tj7A-2wnoA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 2wno TUMOR NECROSIS
FACTOR-INDUCIBLE
GENE 6 PROTEIN
(Homo
sapiens) 		4 / 6 PHE A 229
GLY A 239
TYR A 155
ALA A 237
 None
 1.27A 4yshB-2wnoA:
undetectable		 4yshB-2wnoA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2wno TUMOR NECROSIS
FACTOR-INDUCIBLE
GENE 6 PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 208
LYS A 228
TYR A 196
 None
 1.20A 6gnaA-2wnoA:
undetectable		 6gnaA-2wnoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 2wno TUMOR NECROSIS
FACTOR-INDUCIBLE
GENE 6 PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 208
LYS A 228
TYR A 196
 None
 1.20A 6gnbA-2wnoA:
undetectable		 6gnbA-2wnoA:
19.71