SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wo3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2wo3 EPHRIN-A2
(Homo
sapiens) 		4 / 7 ARG B 143
THR B 173
ILE B  65
ASN B  66
 None
 1.08A 2jc9A-2wo3B:
undetectable		 2jc9A-2wo3B:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2wo3 EPHRIN-A2
(Homo
sapiens) 		4 / 6 GLU B 128
TYR B 148
TYR B 150
PHE B 142
 None
 1.40A 2vmyA-2wo3B:
undetectable		 2vmyA-2wo3B:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 2wo3 EPHRIN-A2
(Homo
sapiens) 		5 / 10 TYR B  68
TRP B 112
SER B  34
ASN B  66
VAL B  63
 None
 1.21A 3burB-2wo3B:
undetectable		 3burB-2wo3B:
17.63