SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2woo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 PHE A 157
VAL A 212
PHE A 216
ILE A 136
PHE A 146
 None
 1.39A 3t3qA-2wooA:
undetectable		 3t3qA-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 VAL A 212
PHE A 216
PHE A 129
ILE A 136
PHE A 146
 None
 1.11A 3t3qA-2wooA:
undetectable		 3t3qA-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 PHE A 157
VAL A 212
PHE A 216
ILE A 136
PHE A 146
 None
 1.39A 3t3qB-2wooA:
undetectable		 3t3qB-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 VAL A 212
PHE A 216
PHE A 129
ILE A 136
PHE A 146
 None
 1.12A 3t3qB-2wooA:
undetectable		 3t3qB-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 PHE A 157
VAL A 212
PHE A 216
ILE A 136
PHE A 146
 None
 1.39A 3t3qC-2wooA:
undetectable		 3t3qC-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 VAL A 212
PHE A 216
PHE A 129
ILE A 136
PHE A 146
 None
 1.11A 3t3qC-2wooA:
undetectable		 3t3qC-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 PHE A 157
VAL A 212
PHE A 216
ILE A 136
PHE A 146
 None
 1.41A 3t3qD-2wooA:
undetectable		 3t3qD-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		5 / 10 VAL A 212
PHE A 216
PHE A 129
ILE A 136
PHE A 146
 None
 1.15A 3t3qD-2wooA:
undetectable		 3t3qD-2wooA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 6 VAL A  24
ASP A 147
ALA A  64
PHE A  65
 None
 1.04A 4nedA-2wooA:
undetectable		 4nedA-2wooA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  91
GLU A  95
SER A  92
ILE A  87
 None
 1.11A 4tvtA-2wooA:
undetectable		 4tvtA-2wooA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE A 242
ILE A 250
PHE A 292
LEU A 158
 None
 0.80A 5fukA-2wooA:
undetectable
5fukB-2wooA:
undetectable		 5fukA-2wooA:
23.62
5fukB-2wooA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A 313
VAL A 227
LEU A  10
LEU A 317
 None
 0.96A 6e43A-2wooA:
undetectable		 6e43A-2wooA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A 313
VAL A 227
LEU A  10
LEU A 317
 None
 1.00A 6e43B-2wooA:
undetectable		 6e43B-2wooA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2woo ATPASE GET3
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A 313
VAL A 227
LEU A  10
LEU A 317
 None
 0.93A 6e43C-2wooA:
undetectable		 6e43C-2wooA:
22.17