SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 2wp7 PPPDE PEPTIDASE
DOMAIN-CONTAINING
PROTEIN 2
(Mus
musculus) 		5 / 12 GLY A 141
MET A  28
LEU A  33
ILE A 151
PHE A 147
 None
 1.21A 4p6xA-2wp7A:
undetectable		 4p6xA-2wp7A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 2wp7 PPPDE PEPTIDASE
DOMAIN-CONTAINING
PROTEIN 2
(Mus
musculus) 		4 / 8 GLY A 158
SER A  56
PHE A  49
SER A  40
 None
 1.00A 4wryA-2wp7A:
undetectable		 4wryA-2wp7A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 2wp7 PPPDE PEPTIDASE
DOMAIN-CONTAINING
PROTEIN 2
(Mus
musculus) 		4 / 8 GLY A 158
SER A  56
PHE A  49
SER A  40
 None
 1.03A 4ws1A-2wp7A:
undetectable		 4ws1A-2wp7A:
22.03