SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 TYR A 115
TRP A 525
GLY A 104
TYR A  95
GLU A 496
None
1.27A 1agmA-2wpgA:
undetectable
1agmA-2wpgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 TYR A 115
TRP A 525
GLY A 104
TYR A  95
GLU A 496
None
1.27A 1agmA-2wpgA:
undetectable
1agmA-2wpgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 10 VAL A 121
TYR A  95
LEU A 127
LEU A 126
VAL A 109
None
1.16A 1cqpA-2wpgA:
undetectable
1cqpB-2wpgA:
undetectable
1cqpA-2wpgA:
13.68
1cqpB-2wpgA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 TYR A 115
TRP A 525
GLY A 104
TYR A  95
GLU A 496
None
1.30A 1gahA-2wpgA:
undetectable
1gahA-2wpgA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 LEU A 497
LEU A 475
ALA A 431
VAL A 541
LEU A 537
None
1.46A 1kt6A-2wpgA:
undetectable
1kt6A-2wpgA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 4 HIS A  35
ASP A  79
ASN A 272
ASP A 312
None
1.38A 1wg8A-2wpgA:
undetectable
1wg8A-2wpgA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 6 LEU A 453
GLY A 448
HIS A 519
ASN A 447
ILE A 395
None
1.32A 1xf1B-2wpgA:
undetectable
1xf1B-2wpgA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 ASN A 156
ARG A 167
LEU A 166
ALA A 164
LEU A 153
None
0.99A 2aclA-2wpgA:
undetectable
2aclE-2wpgA:
undetectable
2aclA-2wpgA:
16.67
2aclE-2wpgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
3 / 3 ALA A 322
THR A 283
PHE A 335
None
0.70A 2c6nB-2wpgA:
undetectable
2c6nB-2wpgA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 TYR A 115
TRP A 525
GLY A 104
TYR A  95
GLU A 496
None
1.33A 2f6dA-2wpgA:
undetectable
2f6dA-2wpgA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 LEU A 106
VAL A 109
VAL A 113
ILE A 171
ALA A 175
None
0.95A 2gj5A-2wpgA:
undetectable
2gj5A-2wpgA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 TYR A 629
ARG A 470
ARG A 573
GLN A 364
None
1.10A 2vxaA-2wpgA:
undetectable
2vxaC-2wpgA:
undetectable
2vxaE-2wpgA:
undetectable
2vxaA-2wpgA:
7.06
2vxaC-2wpgA:
7.06
2vxaE-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.07A 2vxaA-2wpgA:
undetectable
2vxaB-2wpgA:
undetectable
2vxaK-2wpgA:
undetectable
2vxaA-2wpgA:
7.06
2vxaB-2wpgA:
7.06
2vxaK-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.10A 2vxaB-2wpgA:
undetectable
2vxaC-2wpgA:
undetectable
2vxaG-2wpgA:
undetectable
2vxaB-2wpgA:
7.06
2vxaC-2wpgA:
7.06
2vxaG-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 TYR A 629
ARG A 470
ARG A 573
GLN A 364
None
1.10A 2vxaD-2wpgA:
undetectable
2vxaF-2wpgA:
undetectable
2vxaI-2wpgA:
undetectable
2vxaD-2wpgA:
7.06
2vxaF-2wpgA:
7.06
2vxaI-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.08A 2vxaD-2wpgA:
undetectable
2vxaE-2wpgA:
undetectable
2vxaL-2wpgA:
undetectable
2vxaD-2wpgA:
7.06
2vxaE-2wpgA:
7.06
2vxaL-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.10A 2vxaB-2wpgA:
undetectable
2vxaG-2wpgA:
undetectable
2vxaH-2wpgA:
undetectable
2vxaB-2wpgA:
7.06
2vxaG-2wpgA:
7.06
2vxaH-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.07A 2vxaH-2wpgA:
undetectable
2vxaI-2wpgA:
undetectable
2vxaJ-2wpgA:
undetectable
2vxaH-2wpgA:
7.06
2vxaI-2wpgA:
7.06
2vxaJ-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 TYR A 629
ARG A 470
ARG A 573
GLN A 364
None
1.10A 2vxaD-2wpgA:
undetectable
2vxaJ-2wpgA:
undetectable
2vxaL-2wpgA:
undetectable
2vxaD-2wpgA:
7.06
2vxaJ-2wpgA:
7.06
2vxaL-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.08A 2vxaH-2wpgA:
undetectable
2vxaJ-2wpgA:
undetectable
2vxaK-2wpgA:
undetectable
2vxaH-2wpgA:
7.06
2vxaJ-2wpgA:
7.06
2vxaK-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ARG A 573
GLN A 364
TYR A 629
ARG A 470
None
1.07A 2vxaA-2wpgA:
undetectable
2vxaK-2wpgA:
undetectable
2vxaL-2wpgA:
undetectable
2vxaA-2wpgA:
7.06
2vxaK-2wpgA:
7.06
2vxaL-2wpgA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 ILE A 171
PHE A 589
ALA A 360
ALA A 356
THR A 352
None
1.06A 2x2nD-2wpgA:
undetectable
2x2nD-2wpgA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 GLY A 630
LEU A 594
LEU A 369
ALA A 628
VAL A 592
None
1.10A 3av6A-2wpgA:
undetectable
3av6A-2wpgA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 LEU A 478
GLY A 357
LEU A 353
LEU A 361
HIS A 587
None
1.13A 3e23A-2wpgA:
undetectable
3e23A-2wpgA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 LEU A  39
ALA A 311
MET A 267
LEU A 307
VAL A 305
None
0.97A 3gyqB-2wpgA:
2.7
3gyqB-2wpgA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 5 PRO A 486
SER A 563
LEU A 353
SER A 376
None
1.45A 3iluH-2wpgA:
undetectable
3iluH-2wpgA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 GLU A 276
GLY A  94
ALA A 384
ASP A  91
GLY A  85
None
1.12A 3jzjA-2wpgA:
undetectable
3jzjA-2wpgA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 LEU A 594
ALA A 628
SER A 590
ARG A 573
None
0.93A 3kp6A-2wpgA:
undetectable
3kp6A-2wpgA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 ASP A 251
HIS A 301
LEU A 219
CYH A 294
None
0.86A 3lm8B-2wpgA:
2.8
3lm8D-2wpgA:
3.0
3lm8B-2wpgA:
15.54
3lm8D-2wpgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
3 / 3 GLU A 514
GLU A 434
ASN A 447
None
0.86A 3lp9B-2wpgA:
2.7
3lp9D-2wpgA:
1.5
3lp9B-2wpgA:
17.27
3lp9D-2wpgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
6 / 12 PHE A 278
LEU A  75
PHE A  87
ALA A  68
ILE A 313
ALA A 309
None
1.45A 3nxuB-2wpgA:
undetectable
3nxuB-2wpgA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
6 / 9 PHE A 575
LEU A 353
THR A 352
VAL A 372
LEU A 577
ILE A 373
None
1.48A 3tbgD-2wpgA:
undetectable
3tbgD-2wpgA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 5 ARG A 365
VAL A 418
LEU A 415
SER A 414
None
0.99A 4e1gA-2wpgA:
undetectable
4e1gA-2wpgA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
3 / 3 ARG A 390
TRP A 397
GLY A 396
None
0.93A 4e7cA-2wpgA:
undetectable
4e7cA-2wpgA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 5 TYR A  95
LEU A 119
TYR A 542
LEU A 497
None
1.32A 4em2A-2wpgA:
0.0
4em2A-2wpgA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 10 PHE A 589
ALA A 356
LEU A 369
GLY A 366
ALA A 557
None
1.42A 4fe1A-2wpgA:
undetectable
4fe1J-2wpgA:
undetectable
4fe1A-2wpgA:
23.33
4fe1J-2wpgA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 PRO A 489
GLY A 487
LEU A 478
GLY A 357
LEU A 369
None
1.06A 4fp9A-2wpgA:
undetectable
4fp9A-2wpgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 PRO A 489
GLY A 487
LEU A 478
GLY A 357
LEU A 369
None
1.05A 4fp9C-2wpgA:
undetectable
4fp9C-2wpgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 PRO A 489
GLY A 487
LEU A 478
GLY A 357
LEU A 369
None
1.05A 4fp9D-2wpgA:
undetectable
4fp9D-2wpgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 PRO A 489
GLY A 487
LEU A 478
GLY A 357
LEU A 369
None
1.04A 4fp9F-2wpgA:
undetectable
4fp9F-2wpgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
3 / 3 TYR A 285
GLN A 249
TRP A 254
None
1.14A 4kn2C-2wpgA:
undetectable
4kn2C-2wpgA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 LEU A 166
LEU A 162
LEU A 173
ALA A  97
LEU A 126
None
1.18A 4wg0H-2wpgA:
undetectable
4wg0I-2wpgA:
undetectable
4wg0J-2wpgA:
undetectable
4wg0H-2wpgA:
1.96
4wg0I-2wpgA:
1.96
4wg0J-2wpgA:
1.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 ALA A  97
LEU A 126
LEU A 173
LEU A 166
LEU A 162
None
1.19A 4wg0G-2wpgA:
undetectable
4wg0H-2wpgA:
undetectable
4wg0I-2wpgA:
undetectable
4wg0G-2wpgA:
1.96
4wg0H-2wpgA:
1.96
4wg0I-2wpgA:
1.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 LEU A 166
LEU A 162
LEU A 173
ALA A  97
LEU A 126
None
1.17A 4wg0J-2wpgA:
undetectable
4wg0K-2wpgA:
undetectable
4wg0L-2wpgA:
undetectable
4wg0J-2wpgA:
1.96
4wg0K-2wpgA:
1.96
4wg0L-2wpgA:
1.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 11 ALA A  97
LEU A 126
LEU A 173
LEU A 166
LEU A 162
None
1.16A 4wg0I-2wpgA:
undetectable
4wg0J-2wpgA:
undetectable
4wg0K-2wpgA:
undetectable
4wg0I-2wpgA:
1.96
4wg0J-2wpgA:
1.96
4wg0K-2wpgA:
1.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 VAL A 418
ILE A 368
GLY A 366
VAL A 481
LEU A 478
None
1.11A 4y8wA-2wpgA:
undetectable
4y8wA-2wpgA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 VAL A 418
ILE A 368
GLY A 366
VAL A 481
LEU A 478
None
1.06A 4y8wB-2wpgA:
undetectable
4y8wB-2wpgA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 5 ALA A 431
ARG A 474
HIS A 462
ALA A 458
None
1.25A 5a06C-2wpgA:
undetectable
5a06D-2wpgA:
undetectable
5a06C-2wpgA:
18.24
5a06D-2wpgA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 LEU A 478
GLY A 357
ALA A 356
SER A 359
None
0.80A 5f1aA-2wpgA:
undetectable
5f1aA-2wpgA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 7 LEU A 478
GLY A 357
ALA A 356
SER A 359
None
0.84A 5f1aB-2wpgA:
undetectable
5f1aB-2wpgA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 LEU A  46
LEU A  64
TRP A  60
LEU A  61
ALA A 309
None
1.20A 5ieoA-2wpgA:
undetectable
5ieoA-2wpgA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 LEU A  46
LEU A  64
TRP A  60
LEU A  61
ALA A 309
None
1.17A 5iepA-2wpgA:
undetectable
5iepA-2wpgA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 7 VAL A 586
LEU A 626
ALA A 576
LEU A 634
None
0.68A 5jq7A-2wpgA:
undetectable
5jq7A-2wpgA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 ALA A 484
ILE A 373
PHE A 575
GLY A 357
LEU A 477
None
1.04A 5m24A-2wpgA:
undetectable
5m24A-2wpgA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 VAL A 310
ASP A 312
ALA A 264
ARG A 308
LEU A 280
None
1.40A 5syfB-2wpgA:
undetectable
5syfB-2wpgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 8 VAL A 389
PRO A 489
GLY A  94
LEU A  93
None
0.82A 5w3jB-2wpgA:
undetectable
5w3jB-2wpgA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 ILE A 368
PHE A 413
GLY A 406
ALA A 405
LEU A 415
None
1.06A 6dwnD-2wpgA:
undetectable
6dwnD-2wpgA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 HIS A 392
GLU A 323
HIS A 125
LEU A 127
GLY A 139
None
1.35A 6f3mA-2wpgA:
undetectable
6f3mA-2wpgA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
5 / 12 HIS A 392
GLU A 323
HIS A 125
LEU A 127
GLY A 139
None
1.35A 6f3mC-2wpgA:
undetectable
6f3mC-2wpgA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 6 SER A 387
ARG A 579
ALA A 484
ALA A 559
None
1.19A 6ma6A-2wpgA:
undetectable
6ma6A-2wpgA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 6 SER A 414
ALA A 419
THR A 446
ALA A 355
None
1.11A 6ma6A-2wpgA:
undetectable
6ma6A-2wpgA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
2wpg AMYLOSUCRASE OR
ALPHA AMYLASE

(Xanthomonas
campestris)
4 / 7 TRP A  86
ARG A  31
HIS A  35
ASP A  79
None
1.36A 6mn4E-2wpgA:
undetectable
6mn4E-2wpgA:
20.71