SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		9 / 10 ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
PHE A 135
 OLA  A1179 (-3.5A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 (-4.3A)
 0.62A 1aqbA-2wq9A:
31.5		 1aqbA-2wq9A:
93.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A  43
PHE A  77
MET A  88
HIS A 104
PHE A 135
 OLA  A1179 ( 4.0A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 (-4.3A)
 1.00A 1brpA-2wq9A:
32.2		 1brpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 LEU A  37
MET A  73
PHE A  45
LEU A  97
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.9A)
OLA  A1179 (-4.6A)
None
OLA  A1179 (-4.3A)
 1.29A 1brpA-2wq9A:
32.2		 1brpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		12 / 12 LEU A  37
PHE A  45
ALA A  57
MET A  73
GLY A  75
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 (-4.6A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 (-3.8A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 (-4.3A)
 0.39A 1brpA-2wq9A:
32.2		 1brpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FEM_A_REAA184_1
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 10 MET A  73
PHE A  45
LEU A  97
GLN A 117
TYR A 133
 OLA  A1179 ( 4.9A)
OLA  A1179 (-4.6A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
 1.36A 1femA-2wq9A:
22.4		 1femA-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FEM_A_REAA184_1
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 10 VAL A  61
MET A  73
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
GLN A 117
TYR A 133
 None
OLA  A1179 ( 4.9A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
 0.60A 1femA-2wq9A:
22.4		 1femA-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		6 / 11 LEU A  35
PHE A  45
ALA A  55
ALA A  57
MET A  88
TYR A  90
 OLA  A1179 (-4.8A)
OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
 1.35A 1hbpA-2wq9A:
31.3		 1hbpA-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 PHE A  45
ALA A  55
ALA A  57
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
 OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
 0.59A 1hbpA-2wq9A:
31.3		 1hbpA-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 LEU A  37
ALA A  55
ALA A  57
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
 0.52A 1iiuA-2wq9A:
30.5		 1iiuA-2wq9A:
86.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		6 / 7 LEU A  37
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
 0.64A 1kt3A-2wq9A:
25.6		 1kt3A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A  55
ALA A  43
MET A  88
HIS A 104
TYR A 133
 OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.7A)
 1.14A 1kt4A-2wq9A:
31.7		 1kt4A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 12 LEU A  37
ALA A  55
ALA A  57
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
ARG A 121
TYR A 133
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
OLA  A1179 ( 3.7A)
 0.46A 1kt4A-2wq9A:
31.7		 1kt4A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 12 LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
ARG A 121
TYR A 133
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
OLA  A1179 ( 3.7A)
 0.67A 1kt4A-2wq9A:
31.7		 1kt4A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A  55
ALA A  43
MET A  88
HIS A 104
TYR A 133
 OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.7A)
 1.19A 1kt5A-2wq9A:
31.7		 1kt5A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		11 / 12 LEU A  37
PHE A  45
ALA A  55
ALA A  57
MET A  73
MET A  88
TYR A  90
LEU A  97
HIS A 104
ARG A 121
TYR A 133
 OLA  A1179 (-3.4A)
OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
OLA  A1179 ( 3.7A)
 0.45A 1kt5A-2wq9A:
31.7		 1kt5A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
 0.73A 1kt6A-2wq9A:
30.5		 1kt6A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
ARG A 121
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.9A)
 0.71A 1kt7A-2wq9A:
31.7		 1kt7A-2wq9A:
93.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 11 ALA A  43
VAL A  61
MET A  88
HIS A 104
TYR A 133
 OLA  A1179 ( 4.0A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.7A)
 1.41A 1qabE-2wq9A:
26.1		 1qabE-2wq9A:
98.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		9 / 11 LEU A  37
ALA A  57
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
TYR A 133
 OLA  A1179 (-3.4A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.7A)
 0.85A 1qabE-2wq9A:
26.1		 1qabE-2wq9A:
98.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		9 / 11 LEU A  37
VAL A  61
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
TYR A 133
 OLA  A1179 (-3.4A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 ( 3.7A)
 0.97A 1qabE-2wq9A:
26.1		 1qabE-2wq9A:
98.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		11 / 12 ALA A  55
ALA A  57
LEU A  63
MET A  73
GLY A  75
PHE A  77
MET A  88
TYR A  90
LEU A  97
GLN A  98
HIS A 104
 OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 (-3.8A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
OLA  A1179 (-4.5A)
 0.67A 1qabF-2wq9A:
28.2		 1qabF-2wq9A:
98.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 12 LEU A  37
ALA A  43
PHE A  45
ALA A  55
ALA A  57
MET A  73
MET A  88
LEU A  97
GLN A  98
HIS A 104
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
None
None
OLA  A1179 (-4.5A)
 0.57A 1rbpA-2wq9A:
31.6		 1rbpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 12 LEU A  37
ALA A  43
PHE A  45
ALA A  55
ALA A  57
VAL A  61
MET A  88
LEU A  97
GLN A  98
HIS A 104
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
None
OLA  A1179 ( 3.8A)
None
None
OLA  A1179 (-4.5A)
 0.79A 1rbpA-2wq9A:
31.6		 1rbpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 LEU A  63
ALA A  43
ALA A  55
ALA A  57
MET A  73
 None
OLA  A1179 ( 4.0A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
 1.29A 1rbpA-2wq9A:
31.6		 1rbpA-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 10 LEU A  37
ALA A  55
ALA A  57
VAL A  61
MET A  73
LEU A  97
GLN A  98
ASP A 102
GLN A 117
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
None
OLA  A1179 ( 4.9A)
None
None
None
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 0.79A 1rlbE-2wq9A:
31.1		 1rlbE-2wq9A:
92.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 LEU A  37
ALA A  55
ALA A  57
VAL A  61
LEU A  63
MET A  73
MET A  88
TYR A  90
LEU A  97
GLN A  98
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.7A)
None
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
None
 0.82A 1rlbF-2wq9A:
30.5		 1rlbF-2wq9A:
92.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 6 MET A  73
VAL A  93
LEU A  97
PHE A  96
 OLA  A1179 ( 4.9A)
None
None
None
 1.20A 1x8vA-2wq9A:
undetectable		 1x8vA-2wq9A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 10 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.84A 2f16K-2wq9A:
undetectable
2f16L-2wq9A:
undetectable		 2f16K-2wq9A:
20.64
2f16L-2wq9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 10 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.85A 2f16Y-2wq9A:
undetectable
2f16Z-2wq9A:
undetectable		 2f16Y-2wq9A:
20.64
2f16Z-2wq9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 MET A  53
PHE A  77
SER A  46
ALA A  43
GLY A  75
 None
None
CL  A1177 (-4.3A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-3.8A)
 1.40A 2wscA-2wq9A:
undetectable		 2wscA-2wq9A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 MET A  53
PHE A  77
SER A  46
ALA A  43
GLY A  75
 None
None
CL  A1177 (-4.3A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-3.8A)
 1.40A 2wseA-2wq9A:
undetectable		 2wseA-2wq9A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 MET A  53
PHE A  77
SER A  46
ALA A  43
GLY A  75
 None
None
CL  A1177 (-4.3A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-3.8A)
 1.43A 2wsfA-2wq9A:
undetectable		 2wsfA-2wq9A:
13.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		6 / 11 ALA A  43
VAL A  61
MET A  88
HIS A 104
GLN A 117
PHE A 135
 OLA  A1179 ( 4.0A)
None
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 1.28A 3bszE-2wq9A:
30.4		 3bszE-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		10 / 11 LEU A  37
ALA A  43
ALA A  57
MET A  73
MET A  88
LEU A  97
GLN A  98
HIS A 104
GLN A 117
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.0A)
OLA  A1179 ( 3.7A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 0.55A 3bszE-2wq9A:
30.4		 3bszE-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		9 / 11 LEU A  37
ALA A  43
VAL A  61
MET A  88
LEU A  97
GLN A  98
HIS A 104
GLN A 117
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.0A)
None
OLA  A1179 ( 3.8A)
None
None
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 0.88A 3bszE-2wq9A:
30.4		 3bszE-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		6 / 11 ALA A  57
ALA A  55
MET A  88
HIS A 104
GLN A 117
PHE A 135
 OLA  A1179 ( 3.7A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 1.24A 3bszF-2wq9A:
30.4		 3bszF-2wq9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		11 / 11 LEU A  37
ALA A  43
PHE A  45
ALA A  55
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
GLN A 117
PHE A 135
 OLA  A1179 (-3.4A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-4.6A)
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
OLA  A1179 (-4.5A)
OLA  A1179 (-3.5A)
OLA  A1179 (-4.3A)
 0.53A 3bszF-2wq9A:
30.4		 3bszF-2wq9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 MET A  53
PHE A  77
SER A  46
ALA A  43
GLY A  75
 None
None
CL  A1177 (-4.3A)
OLA  A1179 ( 4.0A)
OLA  A1179 (-3.8A)
 1.42A 3lw5A-2wq9A:
undetectable		 3lw5A-2wq9A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.85A 3mg0Y-2wq9A:
undetectable
3mg0Z-2wq9A:
undetectable		 3mg0Y-2wq9A:
20.64
3mg0Z-2wq9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 10 ASP A 108
VAL A 107
VAL A 116
SER A 134
TYR A 114
 GOL  A1180 (-3.5A)
GOL  A1180 (-4.7A)
None
None
None
 1.41A 4ldoA-2wq9A:
undetectable		 4ldoA-2wq9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.83A 5l5zK-2wq9A:
undetectable
5l5zL-2wq9A:
undetectable		 5l5zK-2wq9A:
18.87
5l5zL-2wq9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 9 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.83A 5l5zY-2wq9A:
undetectable
5l5zZ-2wq9A:
undetectable		 5l5zY-2wq9A:
18.87
5l5zZ-2wq9A:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		8 / 8 LEU A  37
ALA A  55
VAL A  61
MET A  73
MET A  88
TYR A  90
GLN A  98
HIS A 104
 OLA  A1179 (-3.4A)
OLA  A1179 (-3.5A)
None
OLA  A1179 ( 4.9A)
OLA  A1179 ( 3.8A)
OLA  A1179 (-3.7A)
None
OLA  A1179 (-4.5A)
 0.68A 5nu7A-2wq9A:
33.1		 5nu7A-2wq9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 116
VAL A 136
TYR A 114
GLN A 149
 None
 1.38A 5qggA-2wq9A:
undetectable		 5qggA-2wq9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 116
VAL A 136
TYR A 114
GLN A 149
 None
 1.34A 5qgoA-2wq9A:
undetectable		 5qgoA-2wq9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 116
VAL A 136
TYR A 114
GLN A 149
 None
 1.33A 5qgpA-2wq9A:
undetectable		 5qgpA-2wq9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 116
VAL A 136
TYR A 114
GLN A 149
 None
 1.40A 5qgqA-2wq9A:
undetectable		 5qgqA-2wq9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 116
VAL A 136
TYR A 114
GLN A 149
 None
 1.39A 5qhbA-2wq9A:
undetectable		 5qhbA-2wq9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		3 / 3 THR A 113
ALA A 148
LYS A 150
 None
None
CL  A1174 (-4.3A)
 0.48A 6fgcA-2wq9A:
undetectable		 6fgcA-2wq9A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		3 / 3 THR A 113
ALA A 148
LYS A 150
 None
None
CL  A1174 (-4.3A)
 0.45A 6fgdA-2wq9A:
undetectable		 6fgdA-2wq9A:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 11 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.86A 6hwdK-2wq9A:
undetectable
6hwdL-2wq9A:
undetectable		 6hwdK-2wq9A:
19.54
6hwdL-2wq9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2wq9 RETINOL-BINDING
PROTEIN 4
(Homo
sapiens) 		5 / 11 ALA A  57
THR A  56
ALA A  55
ALA A  43
GLY A  92
 OLA  A1179 ( 3.7A)
None
OLA  A1179 (-3.5A)
OLA  A1179 ( 4.0A)
None
 0.86A 6hwdY-2wq9A:
undetectable
6hwdZ-2wq9A:
undetectable		 6hwdY-2wq9A:
19.54
6hwdZ-2wq9A:
20.47