SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A  77
HIS A  78
VAL A  81
 None
 0.27A 1lqtB-2wqdA:
undetectable		 1lqtB-2wqdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A  77
HIS A  78
VAL A  81
 None
 0.26A 1lquB-2wqdA:
undetectable		 1lquB-2wqdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ILE A 185
GLY A 206
GLY A   7
ILE A 210
ALA A  10
 None
 1.02A 1vq1B-2wqdA:
undetectable		 1vq1B-2wqdA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 6 LEU A 376
LEU A 379
LEU A 428
LEU A 409
 None
 0.93A 2ab2A-2wqdA:
undetectable		 2ab2A-2wqdA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.38A 2avvB-2wqdA:
undetectable		 2avvB-2wqdA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 THR A 183
ALA A 203
ALA A   9
GLY A 186
ALA A 193
 None
 0.99A 2f16K-2wqdA:
undetectable
2f16L-2wqdA:
undetectable		 2f16K-2wqdA:
16.84
2f16L-2wqdA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 THR A 183
ALA A 203
ALA A   9
GLY A 186
ALA A 193
 None
 0.99A 2f16Y-2wqdA:
undetectable
2f16Z-2wqdA:
undetectable		 2f16Y-2wqdA:
16.84
2f16Z-2wqdA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.43A 2o4kB-2wqdA:
undetectable		 2o4kB-2wqdA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.48A 2q63A-2wqdA:
undetectable		 2q63A-2wqdA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.43A 2q64B-2wqdA:
undetectable		 2q64B-2wqdA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 LEU A 106
VAL A 109
THR A 110
VAL A  81
 None
 0.99A 2qblA-2wqdA:
undetectable		 2qblA-2wqdA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 VAL A 322
ARG A 330
GLY A 295
ALA A 274
 None
 0.84A 2xfsA-2wqdA:
undetectable		 2xfsA-2wqdA:
25.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 VAL A 322
ARG A 330
GLY A 295
ALA A 274
 None
 0.85A 2xh9A-2wqdA:
undetectable		 2xh9A-2wqdA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 LEU A 522
GLY A 454
ILE A 434
VAL A 395
PHE A 444
 None
 1.27A 2zznA-2wqdA:
undetectable		 2zznA-2wqdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 MET A 309
GLU A 312
ASN A 414
 None
 1.01A 3a27A-2wqdA:
undetectable		 3a27A-2wqdA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 ALA A  19
VAL A 231
GLY A 162
VAL A 222
ILE A 220
 None
 1.02A 3ekvB-2wqdA:
undetectable		 3ekvB-2wqdA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.41A 3k4vB-2wqdA:
undetectable		 3k4vB-2wqdA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 10 ASP A 228
VAL A 229
ILE A 204
GLY A 206
ILE A 185
ILE A   5
 None
 1.42A 3nujA-2wqdA:
undetectable		 3nujA-2wqdA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ALA A 508
GLY A 505
GLY A 502
SER A 452
ASP A 523
 None
 1.24A 3ou7D-2wqdA:
undetectable		 3ou7D-2wqdA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 ALA A  19
VAL A 231
GLY A 162
VAL A 222
ILE A 220
 None
 1.07A 3oxvD-2wqdA:
undetectable		 3oxvD-2wqdA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.45A 3tkwB-2wqdA:
undetectable		 3tkwB-2wqdA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 VAL A 229
ILE A 220
GLY A 180
ILE A 201
VAL A 205
ILE A 204
 None
 1.38A 3tl9B-2wqdA:
undetectable		 3tl9B-2wqdA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 THR A 110
LEU A  82
VAL A 135
PHE A  45
ALA A  48
 None
 1.34A 3u9fD-2wqdA:
undetectable
3u9fE-2wqdA:
undetectable		 3u9fD-2wqdA:
18.15
3u9fE-2wqdA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 THR A 110
LEU A  82
VAL A 135
PHE A  45
ALA A  48
 None
 1.37A 3u9fG-2wqdA:
undetectable
3u9fH-2wqdA:
undetectable		 3u9fG-2wqdA:
18.15
3u9fH-2wqdA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 ALA A  19
VAL A 231
GLY A 162
VAL A 222
ILE A 220
 None
 1.11A 4dqcA-2wqdA:
undetectable		 4dqcA-2wqdA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 12 ASP A 228
VAL A 229
ILE A 204
GLY A 206
ILE A 185
ILE A   5
 None
 1.45A 4dqfA-2wqdA:
undetectable		 4dqfA-2wqdA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A 124
VAL A 114
ILE A 132
ALA A  77
 None
 1.02A 4eyzA-2wqdA:
undetectable		 4eyzA-2wqdA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 TYR A 124
VAL A 114
ILE A 132
ALA A  77
 None
 1.00A 4eyzB-2wqdA:
undetectable		 4eyzB-2wqdA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ARG A 373
GLU A 410
ASN A 414
 None
 0.63A 4imaD-2wqdA:
17.8		 4imaD-2wqdA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ARG A 373
GLU A 410
ASN A 414
 None
 0.63A 4ip7D-2wqdA:
16.1		 4ip7D-2wqdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 GLU A  55
ARG A 138
HIS A 142
 None
 0.68A 4kf9A-2wqdA:
undetectable		 4kf9A-2wqdA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 11 ASP A 228
VAL A 229
ILE A 204
GLY A 206
ILE A 185
ILE A   5
 None
 1.42A 4njtA-2wqdA:
undetectable		 4njtA-2wqdA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 LEU A 517
VAL A 487
ILE A 483
MET A 503
 None
 0.87A 4oj4A-2wqdA:
undetectable		 4oj4A-2wqdA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 ALA A  19
VAL A 231
GLY A 162
VAL A 222
ILE A 220
 None
 1.12A 4q1wB-2wqdA:
undetectable		 4q1wB-2wqdA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 11 ASP A 228
VAL A 229
ILE A 204
GLY A 206
ILE A 185
ILE A   5
 None
 1.43A 4rvjA-2wqdA:
undetectable		 4rvjA-2wqdA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		6 / 11 ASP A 228
VAL A 229
ILE A 204
GLY A 206
ILE A 185
ILE A   5
 None
 1.44A 4rvjC-2wqdA:
undetectable		 4rvjC-2wqdA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 6 ARG A 360
ARG A 467
ASP A 457
ASP A 466
 None
 1.20A 4xqeA-2wqdA:
undetectable		 4xqeA-2wqdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 6 ARG A 360
ARG A 467
ASP A 457
ASP A 466
 None
 1.17A 4xqeB-2wqdA:
undetectable		 4xqeB-2wqdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ARG A 360
ARG A 467
ASP A 457
ASP A 466
 None
 1.15A 4xqgA-2wqdA:
undetectable		 4xqgA-2wqdA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ARG A 360
ARG A 467
ASP A 457
ASP A 466
 None
 1.15A 4xqgB-2wqdA:
undetectable		 4xqgB-2wqdA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 5 GLU A 511
THR A 512
THR A 455
LEU A 522
 None
 1.30A 5axaC-2wqdA:
undetectable		 5axaC-2wqdA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ILE A 430
ALA A 436
THR A 437
GLU A 433
 None
 0.86A 5ecnD-2wqdA:
undetectable		 5ecnD-2wqdA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 LEU A   4
GLU A 237
ILE A 230
ILE A 220
ALA A  19
 None
 1.15A 5j7wC-2wqdA:
2.1		 5j7wC-2wqdA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 SER A 494
GLY A 521
ASN A 552
VAL A 555
VAL A 490
 None
 1.02A 5kocB-2wqdA:
undetectable		 5kocB-2wqdA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 THR A 183
ALA A 203
ALA A   9
GLY A 186
ALA A 193
 None
 1.07A 5l5zK-2wqdA:
undetectable
5l5zL-2wqdA:
undetectable		 5l5zK-2wqdA:
15.76
5l5zL-2wqdA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 THR A 183
ALA A 203
ALA A   9
GLY A 186
ALA A 193
 None
 1.07A 5l5zY-2wqdA:
undetectable
5l5zZ-2wqdA:
undetectable		 5l5zY-2wqdA:
15.76
5l5zZ-2wqdA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.93A 5lf3K-2wqdA:
undetectable
5lf3L-2wqdA:
undetectable		 5lf3K-2wqdA:
15.93
5lf3L-2wqdA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.95A 5lf3Y-2wqdA:
undetectable
5lf3Z-2wqdA:
undetectable		 5lf3Y-2wqdA:
15.93
5lf3Z-2wqdA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.85A 5lf7K-2wqdA:
undetectable
5lf7L-2wqdA:
undetectable		 5lf7K-2wqdA:
15.93
5lf7L-2wqdA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.86A 5lf7Y-2wqdA:
undetectable
5lf7Z-2wqdA:
undetectable		 5lf7Y-2wqdA:
15.93
5lf7Z-2wqdA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A  86
PRO A  85
ILE A  88
LEU A  87
 None
 1.14A 5m45A-2wqdA:
0.4		 5m45A-2wqdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A  86
PRO A  85
ILE A  88
LEU A  87
 None
 1.21A 5m45D-2wqdA:
undetectable		 5m45D-2wqdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A  86
PRO A  85
ILE A  88
LEU A  87
 None
 1.13A 5m45G-2wqdA:
0.0		 5m45G-2wqdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A  86
PRO A  85
ILE A  88
LEU A  87
 None
 1.24A 5m45J-2wqdA:
undetectable		 5m45J-2wqdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ARG A 188
THR A 189
ILE A   8
GLY A 187
 None
 0.89A 5nzyA-2wqdA:
1.6		 5nzyA-2wqdA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A 511
THR A 512
THR A 455
LEU A 522
 None
 1.28A 5v96A-2wqdA:
0.3		 5v96A-2wqdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A 511
THR A 512
THR A 455
LEU A 522
 None
 1.27A 5v96B-2wqdA:
0.7		 5v96B-2wqdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A 511
THR A 512
THR A 455
LEU A 522
 None
 1.28A 5v96C-2wqdA:
0.1		 5v96C-2wqdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 4 GLU A 511
THR A 512
THR A 455
LEU A 522
 None
 1.29A 5v96D-2wqdA:
undetectable		 5v96D-2wqdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 GLY A 519
ALA A 551
GLY A 521
LEU A 522
GLU A 492
 None
 1.22A 5vw4A-2wqdA:
undetectable		 5vw4A-2wqdA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		4 / 5 ASN A 281
TYR A 297
VAL A 331
LEU A 323
 None
 1.27A 6a7pA-2wqdA:
undetectable		 6a7pA-2wqdA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 LEU A 323
LYS A 329
TYR A 297
GLY A 293
LEU A 388
 None
 1.29A 6bsiA-2wqdA:
undetectable		 6bsiA-2wqdA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.92A 6hwdK-2wqdA:
undetectable
6hwdL-2wqdA:
undetectable		 6hwdK-2wqdA:
8.91
6hwdL-2wqdA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 THR A 183
ALA A 203
ALA A   9
GLY A 186
GLY A 187
 None
 0.92A 6hwdY-2wqdA:
undetectable
6hwdZ-2wqdA:
undetectable		 6hwdY-2wqdA:
8.91
6hwdZ-2wqdA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2wqd PHOSPHOENOLPYRUVATE-
PROTEIN
PHOSPHOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 GLY A 505
CYH A 504
SER A 526
ILE A 453
MET A 391
 None
 1.09A 6md4A-2wqdA:
undetectable		 6md4A-2wqdA:
8.67