SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2wql MAJOR ALLERGEN DAU C
1
(Daucus
carota) 		5 / 12 ILE A  56
TYR A  81
VAL A  85
ILE A  98
LEU A 143
 None
P4C  A 200 ( 4.5A)
None
PEG  A 201 ( 4.7A)
P4C  A 200 (-4.4A)
 0.67A 1fm4A-2wqlA:
23.0		 1fm4A-2wqlA:
34.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2wql MAJOR ALLERGEN DAU C
1
(Daucus
carota) 		5 / 12 PHE A  20
MET A 102
THR A 100
LEU A  25
ILE A  23
 None
P4C  A 200 ( 4.0A)
P4C  A 200 ( 4.1A)
None
P4C  A 200 (-4.3A)
 1.43A 3elzA-2wqlA:
1.7		 3elzA-2wqlA:
24.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2wql MAJOR ALLERGEN DAU C
1
(Daucus
carota) 		5 / 12 ILE A  56
TYR A  81
VAL A  85
ILE A  98
LEU A 143
 None
P4C  A 200 ( 4.5A)
None
PEG  A 201 ( 4.7A)
P4C  A 200 (-4.4A)
 0.80A 4a84A-2wqlA:
22.9		 4a84A-2wqlA:
36.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 2wql MAJOR ALLERGEN DAU C
1
(Daucus
carota) 		4 / 7 LEU A   8
ALA A 118
THR A 100
SER A  83
 None
PEG  A 201 ( 4.5A)
P4C  A 200 ( 4.1A)
P4C  A 200 ( 3.8A)
 1.08A 4iklA-2wqlA:
undetectable
4iklB-2wqlA:
undetectable		 4iklA-2wqlA:
21.29
4iklB-2wqlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 2wql MAJOR ALLERGEN DAU C
1
(Daucus
carota) 		5 / 10 ILE A 147
LEU A  25
LEU A  79
SER A  21
GLU A  17
 None
 1.28A 5tixB-2wqlA:
undetectable		 5tixB-2wqlA:
20.24