SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.30A 1rs6B-2wqqA:
undetectable		 1rs6B-2wqqA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 LEU A  86
TYR A  81
GLY A 105
 None
 0.64A 2ocuA-2wqqA:
undetectable		 2ocuA-2wqqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 PHE A 254
ALA A 250
GLY A 252
TYR A 251
 None
 1.21A 3bcrA-2wqqA:
undetectable		 3bcrA-2wqqA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 ILE A 130
PHE A 109
HIS A 122
 None
 0.76A 3h0aA-2wqqA:
undetectable		 3h0aA-2wqqA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A 152
GLY A   8
PRO A  11
ALA A 163
ILE A   6
 None
CSF  A1259 (-2.9A)
None
None
None
 1.10A 3jayA-2wqqA:
undetectable		 3jayA-2wqqA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		6 / 12 ILE A 153
GLY A 152
GLY A   8
PRO A  11
ALA A 163
TYR A  18
 CSF  A1259 (-4.4A)
None
CSF  A1259 (-2.9A)
None
None
None
 1.21A 3jayA-2wqqA:
undetectable		 3jayA-2wqqA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PRO A  22
LEU A 211
CYH A 137
ILE A   5
PHE A  49
 None
 1.38A 4a79A-2wqqA:
undetectable		 4a79A-2wqqA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PRO A  22
LEU A 211
CYH A 137
ILE A   5
PHE A  49
 None
 1.36A 4a79B-2wqqA:
undetectable		 4a79B-2wqqA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASP A 154
ILE A 153
GLY A 152
SER A  79
 None
CSF  A1259 (-4.4A)
None
None
 0.92A 4acbB-2wqqA:
undetectable
4acbC-2wqqA:
undetectable		 4acbB-2wqqA:
21.15
4acbC-2wqqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 PHE A  35
TYR A  34
THR A  61
THR A 166
ASP A 242
 None
 1.42A 4ek1B-2wqqA:
undetectable		 4ek1B-2wqqA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 CYH A 210
GLU A  15
ASN A 214
LEU A 216
LEU A 197
 None
 1.38A 4k36B-2wqqA:
undetectable		 4k36B-2wqqA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.37A 4kcnB-2wqqA:
undetectable		 4kcnB-2wqqA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 PHE A  35
TYR A  34
THR A  61
ASP A 242
 None
 1.13A 4l4dA-2wqqA:
undetectable		 4l4dA-2wqqA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 ALA A 196
ILE A 148
LEU A 208
ILE A 206
ILE A 141
 None
 0.94A 5nunA-2wqqA:
undetectable		 5nunA-2wqqA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		5 / 10 PHE A 155
ALA A 218
LEU A 217
ILE A 141
LEU A 112
 None
 1.19A 5oy01-2wqqA:
undetectable
5oy07-2wqqA:
undetectable		 5oy01-2wqqA:
13.97
5oy07-2wqqA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.34A 5vunB-2wqqA:
undetectable		 5vunB-2wqqA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.33A 6auuB-2wqqA:
undetectable		 6auuB-2wqqA:
20.79