SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X1L_C_ADNC601_1 (METHIONYL-TRNA SYNTHETASE)	2wqy	SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT (Gallus gallus)	5 / 11	ALA D 96 ALA D 98 GLY D 92 ASP D 36 ILE D 93	None PEE D 109 ( 4.9A) None None None	1.14A	2x1lC-2wqyD: undetectable	2x1lC-2wqyD: 11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YLG_A_ASCA130_0 (CYTOCHROME C')	2wqy	SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT (Gallus gallus)	4 / 5	ALA D 26 GLY D 32 CYH D 94 LYS D 95	None None PEE D 109 ( 4.8A) None	1.40A	2ylgA-2wqyD: 4.8	2ylgA-2wqyD: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VHU_A_SNLA1001_2 (MINERALOCORTICOID RECEPTOR)	2wqy	SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT (Gallus gallus)	4 / 5	LEU D 43 LEU D 39 LEU D 19 SER D 17	None	1.03A	3vhuA-2wqyD: undetectable	3vhuA-2wqyD: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JT4_A_ASCA202_0 (CYTOCHROME C')	2wqy	SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT (Gallus gallus)	4 / 5	ALA D 26 GLY D 32 CYH D 94 LYS D 95	None None PEE D 109 ( 4.8A) None	1.48A	5jt4A-2wqyD: 4.7	5jt4A-2wqyD: 22.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X1L_C_ADNC601_1","METHIONYL-TRNA SYNTHETASE","2wqy","SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT","Gallus gallus",5,"ALA D  96;ALA D  98;GLY D  92;ASP D  36;ILE D  93","None;PEE D 109 ( 4.9A);None;None;None","1.14A","2x1lC-2wqyD:undetectable","2x1lC-2wqyD:11.42"],["2YLG_A_ASCA130_0","CYTOCHROME C'","2wqy","SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT","Gallus gallus",4,"ALA D  26;GLY D  32;CYH D  94;LYS D  95","None;None;PEE D 109 ( 4.8A);None","1.40A","2ylgA-2wqyD:4.8","2ylgA-2wqyD:22.83"],["3VHU_A_SNLA1001_2","MINERALOCORTICOID RECEPTOR","2wqy","SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT","Gallus gallus",4,"LEU D  43;LEU D  39;LEU D  19;SER D  17","None","1.03A","3vhuA-2wqyD:undetectable","3vhuA-2wqyD:18.12"],["5JT4_A_ASCA202_0","CYTOCHROME C'","2wqy","SUCCINATE DEHYDROGENASE CYTOCHROME B, SMALL SUBUNIT","Gallus gallus",4,"ALA D  26;GLY D  32;CYH D  94;LYS D  95","None;None;PEE D 109 ( 4.8A);None","1.48A","5jt4A-2wqyD:4.7","5jt4A-2wqyD:22.40"]]