SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ws9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 SER 3   7
VAL 3   8
MET 3  15
VAL 3  18
 None
 1.06A 1fduB-2ws93:
undetectable		 1fduB-2ws93:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 2ws9 P1
P1
(Equine
rhinitis
A
virus;
Equine
rhinitis
A
virus) 		3 / 3 PHE 3  40
TYR 3  89
PRO 1 221
 None
 0.99A 1mcnA-2ws93:
undetectable
1mcnB-2ws93:
undetectable
1mcnP-2ws93:
undetectable		 1mcnA-2ws93:
23.43
1mcnB-2ws93:
23.43
1mcnP-2ws93:
0.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 12 ILE 1 195
GLY 1 155
ALA 1 153
VAL 1 158
SER 1 157
 None
 1.10A 1sg9C-2ws91:
undetectable		 1sg9C-2ws91:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.90A 1v55N-2ws91:
undetectable
1v55W-2ws91:
undetectable		 1v55N-2ws91:
19.07
1v55W-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 9 PHE 3  43
VAL 1  30
LEU 1  34
PHE 1 192
LEU 1  71
 None
 1.16A 1wrkA-2ws93:
undetectable
1wrkB-2ws93:
undetectable		 1wrkA-2ws93:
17.86
1wrkB-2ws93:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 SER 3  17
PHE 1  38
ALA 1  67
LEU 1  71
 None
 1.03A 2bxkA-2ws93:
undetectable		 2bxkA-2ws93:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 2ws9 P1
P1
(Equine
rhinitis
A
virus;
Equine
rhinitis
A
virus) 		5 / 12 ASN 1   3
VAL 1   1
GLU 1   9
GLY 1   8
ARG 3 135
 None
 1.44A 2cl5B-2ws91:
undetectable		 2cl5B-2ws91:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.86A 2eijN-2ws91:
undetectable
2eijW-2ws91:
undetectable		 2eijN-2ws91:
19.07
2eijW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 7 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.86A 2eikA-2ws91:
undetectable
2eikJ-2ws91:
undetectable		 2eikA-2ws91:
19.07
2eikJ-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.87A 2eikN-2ws91:
undetectable
2eikW-2ws91:
undetectable		 2eikN-2ws91:
19.07
2eikW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.90A 2eilN-2ws91:
undetectable
2eilW-2ws91:
undetectable		 2eilN-2ws91:
19.07
2eilW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.87A 2einA-2ws91:
undetectable
2einJ-2ws91:
undetectable		 2einA-2ws91:
19.07
2einJ-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 11 THR 1 235
ALA 3  83
SER 3 180
GLY 3 181
SER 3 171
 None
 1.22A 2f162-2ws91:
undetectable		 2f162-2ws91:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 11 THR 1 235
ALA 3  83
SER 3 180
GLY 3 181
SER 3 171
 None
 1.22A 2f16N-2ws91:
undetectable		 2f16N-2ws91:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.89A 3abkA-2ws91:
undetectable
3abkJ-2ws91:
undetectable		 3abkA-2ws91:
19.07
3abkJ-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.89A 3abmN-2ws91:
undetectable
3abmW-2ws91:
undetectable		 3abmN-2ws91:
19.07
3abmW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.83A 3ag3N-2ws91:
undetectable
3ag3W-2ws91:
undetectable		 3ag3N-2ws91:
19.07
3ag3W-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.90A 3asnN-2ws91:
undetectable
3asnW-2ws91:
undetectable		 3asnN-2ws91:
19.07
3asnW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.89A 3asoN-2ws91:
undetectable
3asoW-2ws91:
undetectable		 3asoN-2ws91:
19.07
3asoW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 PHE 1 192
TYR 1 160
VAL 1 169
PRO 1  59
 None
 0.93A 3jq7C-2ws91:
undetectable		 3jq7C-2ws91:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 11 THR 1 235
ALA 3  83
SER 3 180
GLY 3 181
SER 3 171
 None
 1.21A 3mg0N-2ws91:
undetectable		 3mg0N-2ws91:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 12 LEU 1  72
HIS 1 191
TYR 1 160
THR 1 161
SER 1 162
 None
 1.19A 3okxA-2ws91:
undetectable		 3okxA-2ws91:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 12 LEU 1  72
HIS 1 191
TYR 1 160
THR 1 161
SER 1 162
 None
 1.20A 3okxB-2ws91:
undetectable		 3okxB-2ws91:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 5 LEU 3  80
LEU 3 104
MET 3  76
THR 3  88
 None
 1.44A 4do3A-2ws93:
undetectable		 4do3A-2ws93:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 5 ARG 3  34
VAL 1  30
LEU 1  34
SER 1  31
 None
 1.37A 4e1gA-2ws93:
undetectable		 4e1gA-2ws93:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 7 ASN 3 157
PRO 3 159
PHE 3 124
PHE 3 108
 None
 1.35A 4v32A-2ws93:
0.0		 4v32A-2ws93:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 7 ASN 3 157
PRO 3 159
PHE 3 124
PHE 3 108
 None
 1.36A 4v32B-2ws93:
undetectable		 4v32B-2ws93:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 7 TYR 3  61
GLU 3  63
PRO 3  60
PHE 3 110
 None
 1.14A 5aclA-2ws93:
undetectable		 5aclA-2ws93:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 7 TYR 3  61
GLU 3  63
PRO 3  60
PHE 3 120
 None
 1.17A 5aclA-2ws93:
undetectable		 5aclA-2ws93:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 9 ILE 3  44
THR 1  74
LEU 3  93
LEU 1  33
LEU 1  71
 None
 1.10A 5fhzB-2ws93:
undetectable		 5fhzB-2ws93:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2ws9 P1
(Equine
rhinitis
A
virus) 		5 / 10 ILE 3  44
THR 1  74
LEU 3  93
LEU 1  33
LEU 1  71
 None
 1.07A 5fhzC-2ws93:
undetectable		 5fhzC-2ws93:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 4 ASN 3 107
SER 3  52
ALA 3 207
VAL 3 206
 None
 1.22A 5nm5A-2ws93:
undetectable		 5nm5A-2ws93:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 6 LEU 3  93
SER 3  94
PHE 3  97
HIS 3 218
 None
 1.17A 5om3A-2ws93:
undetectable
5om3B-2ws93:
undetectable		 5om3A-2ws93:
17.27
5om3B-2ws93:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 6 LEU 3 104
SER 3 103
PHE 3 214
HIS 1  25
 None
 1.22A 5om3A-2ws93:
undetectable
5om3B-2ws93:
undetectable		 5om3A-2ws93:
17.27
5om3B-2ws93:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.89A 5xdxN-2ws91:
undetectable
5xdxW-2ws91:
undetectable		 5xdxN-2ws91:
19.07
5xdxW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2ws9 P1
(Equine
rhinitis
A
virus) 		4 / 8 LEU 1  84
PHE 1 156
THR 1 198
LEU 1 197
 None
 0.90A 5zcpN-2ws91:
undetectable
5zcpW-2ws91:
undetectable		 5zcpN-2ws91:
19.07
5zcpW-2ws91:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 2ws9 P1
(Equine
rhinitis
A
virus) 		3 / 3 HIS 1 202
ASN 1  47
LEU 1  48
 None
 0.78A 6f7lB-2ws91:
undetectable		 6f7lB-2ws91:
18.74