SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wsb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 11 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 1jb0B-2wsbA:
undetectable		 1jb0B-2wsbA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 159
ILE A  23
GLY A 143
SER A 162
GLY A 190
 POL  A1255 (-3.8A)
NAD  A 500 (-3.9A)
None
None
POL  A1256 (-4.7A)
 0.97A 1kiaA-2wsbA:
8.1		 1kiaA-2wsbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 159
GLY A 147
ALA A 161
SER A 162
TYR A 191
 POL  A1255 (-3.8A)
None
None
None
POL  A1256 (-4.0A)
 1.38A 1kiaD-2wsbA:
6.4		 1kiaD-2wsbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 159
ILE A  23
GLY A 143
SER A 162
GLY A 190
 POL  A1255 (-3.8A)
NAD  A 500 (-3.9A)
None
None
POL  A1256 (-4.7A)
 0.99A 1nbhB-2wsbA:
7.9		 1nbhB-2wsbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 159
ILE A  23
GLY A 143
SER A 162
GLY A 190
 POL  A1255 (-3.8A)
NAD  A 500 (-3.9A)
None
None
POL  A1256 (-4.7A)
 1.01A 1nbiA-2wsbA:
7.9		 1nbiA-2wsbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 159
ILE A  23
GLY A 143
SER A 162
GLY A 190
 POL  A1255 (-3.8A)
NAD  A 500 (-3.9A)
None
None
POL  A1256 (-4.7A)
 1.00A 1nbiB-2wsbA:
7.9		 1nbiB-2wsbA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 4 THR A 194
GLY A  20
ASP A  42
ALA A  93
 NAD  A 500 (-2.7A)
NAD  A 500 ( 3.8A)
NAD  A 500 (-2.8A)
NAD  A 500 (-3.6A)
 1.24A 1sg9A-2wsbA:
6.8		 1sg9A-2wsbA:
23.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		7 / 11 GLY A  18
SER A  21
ASP A  42
ASP A  66
VAL A  67
ALA A  93
VAL A 115
 NAD  A 500 (-3.3A)
NAD  A 500 (-2.7A)
NAD  A 500 (-2.8A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 (-4.1A)
 0.47A 1uayA-2wsbA:
30.6		 1uayA-2wsbA:
31.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		7 / 10 GLY A  18
SER A  21
ASP A  42
ASP A  66
VAL A  67
ALA A  93
VAL A 115
 NAD  A 500 (-3.3A)
NAD  A 500 (-2.7A)
NAD  A 500 (-2.8A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 (-4.1A)
 0.49A 1uayB-2wsbA:
30.9		 1uayB-2wsbA:
31.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 232
PHE A  31
ALA A 228
PRO A 189
LEU A 142
 None
None
None
NAD  A 500 (-3.9A)
NAD  A 500 (-3.7A)
 1.09A 1yi4A-2wsbA:
undetectable		 1yi4A-2wsbA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A  18
ASP A  42
ARG A  43
ASP A  66
ALA A  93
 NAD  A 500 (-3.3A)
NAD  A 500 (-2.8A)
NAD  A 500 (-3.4A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
 0.62A 2bm9E-2wsbA:
5.1		 2bm9E-2wsbA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 5 SER A  92
LEU A  40
GLY A  20
CYH A  28
 NAD  A 500 (-3.1A)
None
NAD  A 500 ( 3.8A)
None
 1.21A 3aiaA-2wsbA:
undetectable
3aiaB-2wsbA:
1.5		 3aiaA-2wsbA:
21.84
3aiaB-2wsbA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A  18
GLY A  20
ASP A  66
VAL A  67
VAL A 115
 NAD  A 500 (-3.3A)
NAD  A 500 ( 3.8A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 (-4.1A)
 0.91A 3dmfA-2wsbA:
8.5		 3dmfA-2wsbA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  27
GLY A  24
ALA A  51
PHE A  31
ALA A  93
 None
None
None
None
NAD  A 500 (-3.6A)
 1.01A 3jb3A-2wsbA:
4.0		 3jb3A-2wsbA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ILE A  88
ALA A 228
PRO A 235
ALA A 236
ALA A  30
 None
 1.10A 3jb3A-2wsbA:
4.0		 3jb3A-2wsbA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 GLU A 208
LEU A 211
ASP A 212
 None
 0.43A 3ko0T-2wsbA:
undetectable		 3ko0T-2wsbA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 11 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 3pcqB-2wsbA:
undetectable		 3pcqB-2wsbA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 11 ARG A  29
GLY A  56
ALA A  47
GLY A  20
GLU A  44
 None
None
NAD  A 500 ( 4.9A)
NAD  A 500 ( 3.8A)
NAD  A 500 ( 4.1A)
 1.23A 4a6nA-2wsbA:
4.7		 4a6nA-2wsbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 11 ILE A  27
ILE A  23
GLY A  22
VAL A 247
GLY A 220
 None
NAD  A 500 (-3.9A)
NAD  A 500 (-3.4A)
None
None
 0.97A 4ac9B-2wsbA:
6.3
4ac9C-2wsbA:
6.3		 4ac9B-2wsbA:
20.75
4ac9C-2wsbA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.45A 4fe1B-2wsbA:
0.7		 4fe1B-2wsbA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		3 / 3 GLU A 103
ASP A 100
ASP A 105
 None
 0.80A 4gc9A-2wsbA:
5.2		 4gc9A-2wsbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		6 / 10 ALA A  51
LEU A  48
ILE A  63
ALA A  65
ALA A  93
THR A  17
 None
None
None
None
NAD  A 500 (-3.6A)
None
 1.26A 4j14A-2wsbA:
undetectable		 4j14A-2wsbA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_2_PQN22002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 4l6v2-2wsbA:
0.1		 4l6v2-2wsbA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		6 / 12 ILE A  88
VAL A  90
ILE A  23
ALA A 226
LEU A 230
LEU A   9
 None
None
NAD  A 500 (-3.9A)
None
None
None
 1.44A 4o1zA-2wsbA:
undetectable		 4o1zA-2wsbA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 6 ILE A 149
THR A 252
HIS A 167
TYR A 159
 None
None
None
POL  A1255 (-3.8A)
 1.02A 4qwpA-2wsbA:
undetectable		 4qwpA-2wsbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 4rkuB-2wsbA:
0.2		 4rkuB-2wsbA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 4xk8B-2wsbA:
0.0		 4xk8B-2wsbA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.46A 4y28B-2wsbA:
0.0		 4y28B-2wsbA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 5 GLY A  18
ASP A  42
ARG A  43
MET A 200
 NAD  A 500 (-3.3A)
NAD  A 500 (-2.8A)
NAD  A 500 (-3.4A)
POL  A1255 ( 4.5A)
 1.47A 5gwkA-2wsbA:
1.5		 5gwkA-2wsbA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A  18
GLY A  20
ASP A  66
VAL A  67
THR A  68
 NAD  A 500 (-3.3A)
NAD  A 500 ( 3.8A)
NAD  A 500 (-3.6A)
NAD  A 500 (-3.6A)
NAD  A 500 ( 4.2A)
 0.75A 5kpcB-2wsbA:
undetectable		 5kpcB-2wsbA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.48A 5oy0b-2wsbA:
undetectable		 5oy0b-2wsbA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		4 / 8 SER A 146
MET A 160
TYR A 159
MET A 196
 POL  A1256 (-2.6A)
None
POL  A1255 (-3.8A)
NAD  A 500 (-3.7A)
 1.46A 5wqpA-2wsbA:
22.8		 5wqpA-2wsbA:
27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA A 161
VAL A 117
MET A 120
GLY A 143
ALA A 188
 None
 1.02A 5xxiA-2wsbA:
undetectable		 5xxiA-2wsbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 142
SER A  92
ASP A  42
ILE A 225
SER A  21
 NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
None
NAD  A 500 (-2.7A)
 1.29A 6dlzA-2wsbA:
4.0
6dlzD-2wsbA:
4.2		 6dlzA-2wsbA:
14.74
6dlzD-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 ILE A 225
SER A  21
LEU A 142
SER A  92
ASP A  42
 None
NAD  A 500 (-2.7A)
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
 1.29A 6dlzB-2wsbA:
4.8
6dlzC-2wsbA:
4.2		 6dlzB-2wsbA:
14.74
6dlzC-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 142
SER A  92
ASP A  42
ILE A 225
SER A  21
 NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
None
NAD  A 500 (-2.7A)
 1.28A 6dm0A-2wsbA:
4.7
6dm0D-2wsbA:
4.8		 6dm0A-2wsbA:
14.74
6dm0D-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 ILE A 225
SER A  21
LEU A 142
SER A  92
ASP A  42
 None
NAD  A 500 (-2.7A)
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
 1.28A 6dm0B-2wsbA:
4.8
6dm0C-2wsbA:
4.7		 6dm0B-2wsbA:
14.74
6dm0C-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 142
SER A  92
ASP A  42
ILE A 225
SER A  21
 NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
None
NAD  A 500 (-2.7A)
 1.29A 6dm1A-2wsbA:
4.2
6dm1D-2wsbA:
4.1		 6dm1A-2wsbA:
14.74
6dm1D-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 10 ILE A 225
SER A  21
LEU A 142
SER A  92
ASP A  42
 None
NAD  A 500 (-2.7A)
NAD  A 500 (-3.7A)
NAD  A 500 (-3.1A)
NAD  A 500 (-2.8A)
 1.29A 6dm1B-2wsbA:
4.9
6dm1C-2wsbA:
4.0		 6dm1B-2wsbA:
14.74
6dm1C-2wsbA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 2wsb GALACTITOL
DEHYDROGENASE
(Rhodobacter
sphaeroides) 		5 / 9 SER A  87
ARG A  37
ALA A  60
LEU A  38
ALA A  36
 None
 1.47A 6hqbB-2wsbA:
0.0		 6hqbB-2wsbA:
13.94