SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 2wse PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II,
CHLOROPLASTIC
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IV A,
CHLOROPLASTIC
(Spinacia
oleracea;
Arabidopsis
thaliana) 		3 / 3 GLU E  42
ILE D 137
ARG E  62
 None
 0.76A 1cd2A-2wseE:
undetectable		 1cd2A-2wseE:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 2wse LHCA3
(Glycine
max) 		4 / 5 VAL 3 206
GLY 3 205
VAL 3 203
TRP 3  92
 None
 1.30A 1tkqB-2wse3:
undetectable		 1tkqB-2wse3:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 2wse PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 5 ALA D  40
ALA D  78
TYR D  46
GLN D 110
 None
 1.14A 1xl6A-2wseD:
undetectable
1xl6B-2wseD:
undetectable		 1xl6A-2wseD:
23.29
1xl6B-2wseD:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2wse LHCA3
(Glycine
max) 		5 / 9 GLY 3  62
TYR 3  64
GLY 3  57
ARG 3 188
ILE 3  60
 None
CLA  31222 ( 2.6A)
None
CLA  31223 ( 4.0A)
None
 1.40A 2y7wA-2wse3:
undetectable		 2y7wA-2wse3:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 2wse LHCA3
(Glycine
max) 		4 / 4 GLU 3  43
GLY 3  44
THR 3  45
GLU 3  50
 None
 1.08A 3e9xA-2wse3:
undetectable		 3e9xA-2wse3:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 2wse PHOTOSYSTEM I
REACTION CENTER
SUBUNIT II,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 PRO D  25
THR D  24
LEU D  74
 None
 0.76A 3ttrA-2wseD:
undetectable		 3ttrA-2wseD:
19.19