SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wsh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_A_ACTA601_0
(VANILLYL-ALCOHOL
OXIDASE)		 2wsh ENDONUCLEASE II
(Escherichia
virus
T4) 		4 / 5 TYR A  61
ILE A  39
TYR A  37
ARG A  57
 None
None
PO4  A1133 (-4.7A)
PO4  A1133 (-3.6A)
 1.29A 1qltA-2wshA:
0.0		 1qltA-2wshA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 2wsh ENDONUCLEASE II
(Escherichia
virus
T4) 		5 / 12 TYR A  37
ILE A  39
VAL A  46
ASN A 130
PHE A  92
 PO4  A1133 (-4.7A)
None
None
None
None
 1.31A 3a8iB-2wshA:
undetectable		 3a8iB-2wshA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 2wsh ENDONUCLEASE II
(Escherichia
virus
T4) 		5 / 9 VAL A  90
ILE A  39
ALA A  78
THR A  75
VAL A  46
 None
 1.16A 3me6C-2wshA:
undetectable		 3me6C-2wshA:
14.88