SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		3 / 3 THR A 125
PRO A 127
PRO A  95
 None
 0.52A 2d55C-2wsjA:
undetectable		 2d55C-2wsjA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		3 / 3 ARG A  48
ASP A  37
ASP A 149
 IPA  A1180 ( 3.8A)
NA  A1181 ( 3.7A)
None
 0.80A 2ejtA-2wsjA:
undetectable		 2ejtA-2wsjA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		4 / 7 LEU A  79
VAL A  36
TYR A  26
TYR A  38
 IPA  A1179 (-4.4A)
None
IPA  A1179 ( 4.0A)
IPA  A1179 ( 4.5A)
 1.05A 4b3qA-2wsjA:
undetectable		 4b3qA-2wsjA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		3 / 3 GLU A  27
ARG A  39
HIS A  41
 None
 0.82A 4kf9A-2wsjA:
undetectable		 4kf9A-2wsjA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		4 / 7 PHE A  94
ILE A 104
SER A  71
THR A  75
 None
None
NA  A1182 (-2.9A)
IPA  A1180 ( 4.3A)
 0.97A 5vkqA-2wsjA:
undetectable
5vkqD-2wsjA:
undetectable		 5vkqA-2wsjA:
6.99
5vkqD-2wsjA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		4 / 7 SER A  71
THR A  75
PHE A  94
ILE A 104
 NA  A1182 (-2.9A)
IPA  A1180 ( 4.3A)
None
None
 0.97A 5vkqA-2wsjA:
undetectable
5vkqB-2wsjA:
undetectable		 5vkqA-2wsjA:
6.99
5vkqB-2wsjA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		4 / 8 SER A  71
THR A  75
PHE A  94
ILE A 104
 NA  A1182 (-2.9A)
IPA  A1180 ( 4.3A)
None
None
 0.96A 5vkqB-2wsjA:
undetectable
5vkqC-2wsjA:
undetectable		 5vkqB-2wsjA:
6.99
5vkqC-2wsjA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2wsj P-COUMARIC ACID
DECARBOXYLASE
(Lactobacillus
plantarum) 		4 / 7 SER A  71
THR A  75
PHE A  94
ILE A 104
 NA  A1182 (-2.9A)
IPA  A1180 ( 4.3A)
None
None
 0.96A 5vkqC-2wsjA:
undetectable
5vkqD-2wsjA:
undetectable		 5vkqC-2wsjA:
6.99
5vkqD-2wsjA:
6.99