SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wsk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 8 LEU A 503
ARG A 417
PHE A 418
GLY A 416
 None
 1.02A 1fapB-2wskA:
undetectable		 1fapB-2wskA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 PRO A  62
LEU A   4
TYR A  60
GLY A  51
LEU A  35
 None
 1.38A 1fkpA-2wskA:
undetectable		 1fkpA-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 321
ALA A 317
LEU A 353
HIS A 266
LEU A 306
 None
 1.35A 1gwrB-2wskA:
undetectable		 1gwrB-2wskA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 PHE A 104
ASN A 284
ASP A 271
LEU A 270
GLY A 274
 None
 1.32A 1ju6A-2wskA:
undetectable		 1ju6A-2wskA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 PHE A 104
ASN A 284
ASP A 271
LEU A 270
GLY A 274
 None
 1.33A 1ju6D-2wskA:
undetectable		 1ju6D-2wskA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 PRO A  62
LEU A   4
TYR A  60
GLY A  51
LEU A  35
 None
 1.48A 1lwcA-2wskA:
undetectable		 1lwcA-2wskA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 ARG A 397
ILE A 436
TRP A 392
 None
 1.18A 1m8eB-2wskA:
undetectable		 1m8eB-2wskA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.85A 1pxxC-2wskA:
undetectable		 1pxxC-2wskA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.70A 1rl8B-2wskA:
undetectable		 1rl8B-2wskA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 ILE A 193
LEU A 161
ALA A 514
GLU A 517
 None
 1.13A 1xvaA-2wskA:
undetectable
1xvaB-2wskA:
undetectable		 1xvaA-2wskA:
18.42
1xvaB-2wskA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 6 ALA A 514
GLU A 517
ILE A 193
LEU A 161
 None
 1.04A 1xvaA-2wskA:
undetectable
1xvaB-2wskA:
undetectable		 1xvaA-2wskA:
18.42
1xvaB-2wskA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 196
LEU A 188
VAL A 158
GLY A 174
ARG A 173
 None
 1.49A 1y4lB-2wskA:
undetectable		 1y4lB-2wskA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 2avvA-2wskA:
undetectable		 2avvA-2wskA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 2f80A-2wskA:
undetectable		 2f80A-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 2f80B-2wskA:
undetectable		 2f80B-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 2f81B-2wskA:
undetectable		 2f81B-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 2hs2B-2wskA:
undetectable		 2hs2B-2wskA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.89A 2idwB-2wskA:
undetectable		 2idwB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.87A 2ienA-2wskA:
undetectable		 2ienA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 2ienB-2wskA:
undetectable		 2ienB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 TRP A 569
ALA A 419
TRP A 570
ALA A 420
 None
 1.17A 2jstA-2wskA:
undetectable
2jstB-2wskA:
undetectable		 2jstA-2wskA:
6.51
2jstB-2wskA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 TRP A 570
ALA A 420
TRP A 569
ALA A 419
 None
 1.18A 2jstA-2wskA:
undetectable
2jstB-2wskA:
undetectable		 2jstA-2wskA:
6.51
2jstB-2wskA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.76A 2nmyB-2wskA:
undetectable		 2nmyB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 2nmzA-2wskA:
undetectable		 2nmzA-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 2nmzB-2wskA:
undetectable		 2nmzB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 ILE A 256
LEU A 251
ALA A 195
PHE A 244
 None
 1.01A 2opxA-2wskA:
undetectable		 2opxA-2wskA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 2q64A-2wskA:
undetectable		 2q64A-2wskA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 2q64B-2wskA:
undetectable		 2q64B-2wskA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 2qakA-2wskA:
undetectable		 2qakA-2wskA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.78A 2rkfA-2wskA:
undetectable		 2rkfA-2wskA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 2rkfB-2wskA:
undetectable		 2rkfB-2wskA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 2rkgA-2wskA:
undetectable		 2rkgA-2wskA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 2rkgB-2wskA:
undetectable		 2rkgB-2wskA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 4 ARG A  73
GLY A  71
GLU A  44
SER A  27
 None
 1.35A 2xctS-2wskA:
undetectable
2xctU-2wskA:
undetectable		 2xctS-2wskA:
23.57
2xctU-2wskA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 ARG A 334
ASP A 336
GLU A 371
HIS A 442
ASP A 443
 None
 0.86A 3aicA-2wskA:
2.6		 3aicA-2wskA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 ARG A 334
ASP A 336
GLU A 371
HIS A 442
ASP A 443
 None
 0.88A 3aicE-2wskA:
5.3		 3aicE-2wskA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 ARG A 334
ASP A 336
GLU A 371
HIS A 442
ASP A 443
 None
 0.89A 3aicH-2wskA:
5.3		 3aicH-2wskA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 3bvbA-2wskA:
undetectable		 3bvbA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.75A 3bvbB-2wskA:
undetectable		 3bvbB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.70A 3cywA-2wskA:
undetectable		 3cywA-2wskA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 3cywB-2wskA:
undetectable		 3cywB-2wskA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 3d1xB-2wskA:
undetectable		 3d1xB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 3d1zB-2wskA:
undetectable		 3d1zB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 3d20B-2wskA:
undetectable		 3d20B-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 7 THR A 151
THR A 509
ILE A 436
ILE A 369
 None
 0.86A 3deuA-2wskA:
1.1		 3deuA-2wskA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 3ekpD-2wskA:
undetectable		 3ekpD-2wskA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.86A 3ektC-2wskA:
undetectable		 3ektC-2wskA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 3ektD-2wskA:
undetectable		 3ektD-2wskA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.86A 3el1A-2wskA:
undetectable		 3el1A-2wskA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 3jvyA-2wskA:
undetectable		 3jvyA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 3jvyB-2wskA:
undetectable		 3jvyB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 3jw2A-2wskA:
undetectable		 3jw2A-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.78A 3k4vB-2wskA:
undetectable		 3k4vB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 6 VAL A 258
LEU A 538
ILE A 168
LEU A 198
 None
 0.97A 3kk6A-2wskA:
undetectable		 3kk6A-2wskA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.86A 3ln1D-2wskA:
undetectable		 3ln1D-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.73A 3lzsA-2wskA:
undetectable		 3lzsA-2wskA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3lzsB-2wskA:
undetectable		 3lzsB-2wskA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3lzuA-2wskA:
undetectable		 3lzuA-2wskA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3lzuB-2wskA:
undetectable		 3lzuB-2wskA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.81A 3n8yA-2wskA:
undetectable		 3n8yA-2wskA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3ndtB-2wskA:
undetectable		 3ndtB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.87A 3ndtD-2wskA:
undetectable		 3ndtD-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 3nduB-2wskA:
undetectable		 3nduB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.92A 3nduD-2wskA:
undetectable		 3nduD-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 3nu3A-2wskA:
undetectable		 3nu3A-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3nu3B-2wskA:
undetectable		 3nu3B-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 3nu4B-2wskA:
undetectable		 3nu4B-2wskA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 3nu6B-2wskA:
undetectable		 3nu6B-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3nujB-2wskA:
undetectable		 3nujB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.76A 3nuoB-2wskA:
undetectable		 3nuoB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 ARG A 397
ILE A 436
TRP A 392
 None
 1.14A 3nw2A-2wskA:
undetectable		 3nw2A-2wskA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 1.00A 3oxcB-2wskA:
undetectable		 3oxcB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 3pwmA-2wskA:
undetectable		 3pwmA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 3pwmB-2wskA:
undetectable		 3pwmB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.91A 3pwrA-2wskA:
undetectable		 3pwrA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 3pwrB-2wskA:
undetectable		 3pwrB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 7 ILE A 193
LEU A 188
LEU A 179
VAL A 201
 None
 0.86A 3r9vA-2wskA:
undetectable
3r9vB-2wskA:
undetectable		 3r9vA-2wskA:
17.55
3r9vB-2wskA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 7 ILE A 496
LEU A 447
LEU A 512
HIS A 497
 None
 1.01A 3r9vA-2wskA:
undetectable
3r9vB-2wskA:
undetectable		 3r9vA-2wskA:
17.55
3r9vB-2wskA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 3s43B-2wskA:
undetectable		 3s43B-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.88A 3s45B-2wskA:
undetectable		 3s45B-2wskA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.87A 3s54A-2wskA:
undetectable		 3s54A-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.83A 3s54B-2wskA:
undetectable		 3s54B-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 6 LEU A 196
VAL A 258
PHE A 244
VAL A 158
 None
 1.13A 3soaA-2wskA:
undetectable		 3soaA-2wskA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 3tkgA-2wskA:
undetectable		 3tkgA-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 3tkgB-2wskA:
undetectable		 3tkgB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 3tkwA-2wskA:
undetectable		 3tkwA-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 3tkwB-2wskA:
undetectable		 3tkwB-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 3tl9A-2wskA:
undetectable		 3tl9A-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.87A 3tl9B-2wskA:
undetectable		 3tl9B-2wskA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 7 LEU A 513
TYR A 154
HIS A 518
HIS A 520
 None
 1.38A 4arcA-2wskA:
1.9		 4arcA-2wskA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.94A 4coxA-2wskA:
undetectable		 4coxA-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.96A 4coxB-2wskA:
undetectable		 4coxB-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.95A 4coxC-2wskA:
undetectable		 4coxC-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.95A 4coxD-2wskA:
0.0		 4coxD-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 4dqfB-2wskA:
undetectable		 4dqfB-2wskA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.70A 4hlaA-2wskA:
undetectable		 4hlaA-2wskA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.74A 4hlaB-2wskA:
undetectable		 4hlaB-2wskA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 4jecA-2wskA:
undetectable		 4jecA-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.78A 4jecB-2wskA:
undetectable		 4jecB-2wskA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 ILE A 375
GLY A 379
ALA A 370
ARG A 334
ASP A 336
 None
 0.91A 4kicB-2wskA:
undetectable		 4kicB-2wskA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 6 ARG A 343
ASN A 307
ASP A 283
GLY A  83
THR A 305
 None
 1.40A 4l1aB-2wskA:
undetectable		 4l1aB-2wskA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.84A 4ll3B-2wskA:
undetectable		 4ll3B-2wskA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 4ll3A-2wskA:
undetectable		 4ll3A-2wskA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.89A 4otyA-2wskA:
undetectable		 4otyA-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.89A 4otyB-2wskA:
0.0		 4otyB-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 PRO A  62
LEU A  61
HIS A  45
 None
 0.65A 4pevA-2wskA:
undetectable		 4pevA-2wskA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 ILE A 282
TYR A  70
VAL A 131
LEU A   4
LEU A  49
 None
 1.22A 4qztA-2wskA:
undetectable		 4qztA-2wskA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 TYR A 316
TYR A 288
GLU A 269
LEU A 306
 None
 1.35A 4qztB-2wskA:
undetectable		 4qztB-2wskA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.92A 4rrwA-2wskA:
undetectable		 4rrwA-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.91A 4rrwB-2wskA:
undetectable		 4rrwB-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.93A 4rrwC-2wskA:
0.0		 4rrwC-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.92A 4rrzA-2wskA:
undetectable		 4rrzA-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.91A 4rrzB-2wskA:
undetectable		 4rrzB-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.93A 4rrzC-2wskA:
0.0		 4rrzC-2wskA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 4rvjB-2wskA:
undetectable		 4rvjB-2wskA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 9 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.79A 4rvjD-2wskA:
undetectable		 4rvjD-2wskA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 ALA A 234
TYR A 233
HIS A 266
PHE A 204
 None
 1.21A 4ze2A-2wskA:
undetectable		 4ze2A-2wskA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 THR A 551
HIS A 157
LEU A 538
 None
 0.70A 5axdA-2wskA:
undetectable		 5axdA-2wskA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 THR A 551
HIS A 157
LEU A 538
 None
 0.66A 5axdC-2wskA:
undetectable		 5axdC-2wskA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 PHE A 550
HIS A 556
LEU A 504
PRO A 632
 None
 1.41A 5csyB-2wskA:
18.5		 5csyB-2wskA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 LEU A 321
ALA A 317
LEU A 353
HIS A 266
LEU A 306
 None
 1.33A 5dx3A-2wskA:
undetectable		 5dx3A-2wskA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 6 PHE A 403
SER A 495
HIS A 650
LEU A 405
 None
 1.21A 5dzka-2wskA:
1.6
5dzko-2wskA:
undetectable		 5dzka-2wskA:
16.17
5dzko-2wskA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 SER A 495
ALA A 498
HIS A 650
LEU A 405
 None
 1.46A 5dzkb-2wskA:
1.2
5dzkp-2wskA:
undetectable		 5dzkb-2wskA:
16.17
5dzkp-2wskA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 5 SER A 495
ALA A 498
HIS A 650
LEU A 405
 None
 1.46A 5dzkc-2wskA:
1.2
5dzkq-2wskA:
undetectable		 5dzkc-2wskA:
16.17
5dzkq-2wskA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		4 / 6 PHE A 403
SER A 495
HIS A 650
LEU A 405
 None
 1.22A 5dzke-2wskA:
1.2
5dzks-2wskA:
undetectable		 5dzke-2wskA:
16.17
5dzks-2wskA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 6 PHE A 403
SER A 495
ALA A 498
HIS A 650
LEU A 405
 None
 1.43A 5dzkg-2wskA:
undetectable
5dzku-2wskA:
undetectable		 5dzkg-2wskA:
16.17
5dzku-2wskA:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 5e5jA-2wskA:
undetectable		 5e5jA-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.77A 5e5jB-2wskA:
undetectable		 5e5jB-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.81A 5e5kA-2wskA:
undetectable		 5e5kA-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.80A 5e5kB-2wskA:
undetectable		 5e5kB-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 TYR A 221
ASP A 261
TRP A 219
ILE A 436
ILE A 369
 None
 1.15A 5hw8A-2wskA:
undetectable
5hw8D-2wskA:
undetectable		 5hw8A-2wskA:
11.48
5hw8D-2wskA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.90A 5ikrA-2wskA:
undetectable		 5ikrA-2wskA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.84A 5iktA-2wskA:
undetectable		 5iktA-2wskA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.86A 5jvzB-2wskA:
undetectable		 5jvzB-2wskA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 SER A 421
TRP A 579
GLY A 412
ALA A 413
LEU A 409
 None
 0.83A 5kirB-2wskA:
undetectable		 5kirB-2wskA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 HIS A  84
ASP A 283
HIS A  29
 None
 0.85A 5n1tW-2wskA:
2.2		 5n1tW-2wskA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 GLY A  59
THR A  24
ASN A  22
 None
 0.68A 5odiG-2wskA:
2.5		 5odiG-2wskA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 5t2zB-2wskA:
undetectable		 5t2zB-2wskA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.82A 5t8hA-2wskA:
undetectable		 5t8hA-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.78A 5t8hB-2wskA:
undetectable		 5t8hB-2wskA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 10 TRP A 148
PRO A 147
ALA A 195
GLY A 332
ILE A 259
 None
 1.23A 5vyhA-2wskA:
undetectable		 5vyhA-2wskA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		3 / 3 TYR A 163
ARG A 173
THR A 175
 None
 1.04A 5z84J-2wskA:
undetectable		 5z84J-2wskA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 GLY A 379
ALA A 376
ALA A 339
ALA A 338
PHE A 385
 None
 0.88A 5zw4A-2wskA:
undetectable		 5zw4A-2wskA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.87A 6dgxA-2wskA:
undetectable		 6dgxA-2wskA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.89A 6dh3A-2wskA:
undetectable		 6dh3A-2wskA:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.85A 6difB-2wskA:
undetectable		 6difB-2wskA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 12 LEU A 188
GLY A 255
ALA A 254
ILE A 248
ILE A 185
 None
 0.86A 6dilB-2wskA:
undetectable		 6dilB-2wskA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)		 2wsk GLYCOGEN DEBRANCHING
ENZYME
(Escherichia
coli) 		5 / 11 PHE A 104
ASN A 284
ASP A 271
LEU A 270
GLY A 274
 None
 1.35A 6r2eF-2wskA:
undetectable		 6r2eF-2wskA:
19.26