SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wst'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 GLY A 174
GLY A 141
PHE A 278
PHE A 270
 None
 1.03A 2qx6A-2wstA:
undetectable
2qx6B-2wstA:
undetectable		 2qx6A-2wstA:
20.16
2qx6B-2wstA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 8 GLY A 152
PHE A 266
GLY A 286
PHE A 285
 None
 0.80A 3ko0O-2wstA:
undetectable
3ko0Q-2wstA:
undetectable		 3ko0O-2wstA:
14.55
3ko0Q-2wstA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 10 VAL A 131
LEU A 164
GLY A 141
VAL A 160
GLY A 162
 None
 1.20A 3ls4H-2wstA:
undetectable		 3ls4H-2wstA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		3 / 3 GLN A 171
THR A 172
THR A 269
 None
 0.79A 4fu9A-2wstA:
undetectable		 4fu9A-2wstA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		3 / 3 GLN A 171
THR A 172
THR A 269
 None
 0.75A 4fufA-2wstA:
undetectable		 4fufA-2wstA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 11 ILE A 250
PHE A 266
LEU A 143
TYR A 287
THR A 254
 None
 1.39A 4i1nA-2wstA:
undetectable		 4i1nA-2wstA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2wst PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 5 VAL A 205
THR A 203
VAL A 117
LEU A 214
 None
 0.91A 6bqgA-2wstA:
undetectable		 6bqgA-2wstA:
14.50