SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wsu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOF_A_PNNA1312_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 11 PHE A 633
ASP A 514
THR A 415
HIS A 670
VAL A 577
 None
None
NO3  A1688 (-3.0A)
None
None
 1.20A 1uofA-2wsuA:
undetectable		 1uofA-2wsuA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 THR A 560
THR A 639
ILE A 666
LEU A 663
 None
 0.89A 3deuB-2wsuA:
undetectable		 3deuB-2wsuA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		6 / 6 HIS A 435
ASN A 437
ARG A 439
ASN A 451
TRP A 459
GLU A 462
 None
 0.59A 3galA-2wsuA:
19.7		 3galA-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 HIS A 593
ASN A 595
ASN A 609
TRP A 616
 GOL  A1686 (-4.0A)
None
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
 0.54A 3galA-2wsuA:
19.7		 3galA-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 HIS A 593
ASN A 609
TRP A 616
GLU A 619
 GOL  A1686 (-4.0A)
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
GOL  A1686 (-4.2A)
 0.84A 3galA-2wsuA:
19.7		 3galA-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		6 / 6 HIS A 435
ASN A 437
ARG A 439
ASN A 451
TRP A 459
GLU A 462
 None
 0.59A 3galB-2wsuA:
19.6		 3galB-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 HIS A 593
ASN A 595
ASN A 609
TRP A 616
 GOL  A1686 (-4.0A)
None
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
 0.58A 3galB-2wsuA:
19.6		 3galB-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 HIS A 593
ASN A 609
TRP A 616
GLU A 619
 GOL  A1686 (-4.0A)
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
GOL  A1686 (-4.2A)
 0.76A 3galB-2wsuA:
19.6		 3galB-2wsuA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 4 PRO A 495
THR A 490
GLY A 405
THR A 404
 None
 1.06A 3ib1A-2wsuA:
undetectable		 3ib1A-2wsuA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 12 GLY A 513
GLY A 673
ALA A 418
THR A 413
LEU A 515
 None
 1.20A 3mteA-2wsuA:
undetectable		 3mteA-2wsuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 7 VAL A 491
PHE A 470
VAL A 438
ILE A 480
 None
 0.95A 3zjqA-2wsuA:
undetectable		 3zjqA-2wsuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 7 VAL A 491
PHE A 470
VAL A 438
ILE A 480
 None
 0.91A 3zjqB-2wsuA:
undetectable		 3zjqB-2wsuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 12 VAL A 497
THR A 422
ILE A 448
PHE A 436
HIS A 435
 None
 1.23A 4c49B-2wsuA:
undetectable		 4c49B-2wsuA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 8 SER A 512
PHE A 499
ILE A 489
VAL A 497
 None
 1.00A 4dx7B-2wsuA:
undetectable		 4dx7B-2wsuA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 7 LEU A 663
ALA A 591
ILE A 620
THR A 639
 None
 0.90A 4eyrA-2wsuA:
undetectable		 4eyrA-2wsuA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 8 LEU A 561
GLU A 681
THR A 634
LEU A 638
 None
 0.94A 4iizB-2wsuA:
undetectable		 4iizB-2wsuA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 8 ILE A 408
ALA A 509
VAL A 402
PRO A 403
 None
 0.71A 4jltA-2wsuA:
undetectable		 4jltA-2wsuA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.06A 5bphA-2wsuA:
undetectable		 5bphA-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 7 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.10A 5bphB-2wsuA:
undetectable		 5bphB-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 ARG A 453
GLY A 455
SER A 431
LEU A 432
 None
 1.02A 5bphD-2wsuA:
undetectable		 5bphD-2wsuA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 12 PRO A 626
ILE A 637
VAL A 596
LEU A 579
THR A 654
 None
 1.31A 5bykA-2wsuA:
undetectable		 5bykA-2wsuA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 12 ILE A 666
GLY A 555
HIS A 682
VAL A 684
ALA A 591
 None
 1.18A 5n0oA-2wsuA:
undetectable		 5n0oA-2wsuA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 4 TYR A 487
SER A 452
GLN A 504
THR A 427
 None
 1.46A 5n0tB-2wsuA:
0.0		 5n0tB-2wsuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 7 VAL A 438
LEU A 571
PHE A 394
LEU A 520
 None
NO3  A1687 (-4.0A)
None
None
 1.09A 6aycA-2wsuA:
undetectable		 6aycA-2wsuA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		7 / 7 HIS A 435
ASN A 437
ARG A 439
ASN A 451
TRP A 459
GLU A 462
ARG A 464
 None
 0.55A 6b8kA-2wsuA:
22.5		 6b8kA-2wsuA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 7 HIS A 593
ASN A 595
ASN A 609
TRP A 616
GLU A 619
 GOL  A1686 (-4.0A)
None
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
GOL  A1686 (-4.2A)
 0.88A 6b8kA-2wsuA:
22.5		 6b8kA-2wsuA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		7 / 8 HIS A 435
ASN A 437
ARG A 439
ASN A 451
TRP A 459
GLU A 462
ARG A 464
 None
 0.68A 6b94A-2wsuA:
18.5		 6b94A-2wsuA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 8 HIS A 593
ASN A 595
ASN A 609
TRP A 616
GLU A 619
 GOL  A1686 (-4.0A)
None
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
GOL  A1686 (-4.2A)
 0.79A 6b94A-2wsuA:
18.5		 6b94A-2wsuA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		7 / 10 HIS A 435
ASN A 437
ARG A 439
ASN A 451
TRP A 459
GLU A 462
ARG A 464
 None
 0.57A 6b94A-2wsuA:
18.5
6b94B-2wsuA:
17.9		 6b94A-2wsuA:
13.76
6b94B-2wsuA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		5 / 10 HIS A 593
ASN A 595
ASN A 609
TRP A 616
GLU A 619
 GOL  A1686 (-4.0A)
None
GOL  A1686 (-3.7A)
GOL  A1686 (-3.7A)
GOL  A1686 (-4.2A)
 0.78A 6b94A-2wsuA:
18.5
6b94B-2wsuA:
17.9		 6b94A-2wsuA:
13.76
6b94B-2wsuA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 2wsu PUTATIVE FIBER
PROTEIN
(Porcine
mastadenovirus
B) 		4 / 6 ILE A 482
TYR A 487
LEU A 425
VAL A 402
 None
 0.96A 6f6jA-2wsuA:
undetectable		 6f6jA-2wsuA:
undetectable