SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wtz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CBR_B_REAB200_1 (CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	ALA A 102 ALA A 100 PRO A 74 VAL A 62 ARG A 60	None	1.28A	1cbrB-2wtzA: undetectable	1cbrB-2wtzA: 13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_3 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 5	LEU A 414 VAL A 497 LEU A 390 GLN A 380	None	0.80A	1fbmE-2wtzA: undetectable	1fbmE-2wtzA: 9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KGL_A_RTLA175_1 (CELLULAR RETINOL-BINDING PROTEIN TYPE I)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 7	LEU A 228 ILE A 178 THR A 196 MET A 219	None None UAG A1498 (-4.7A) None	1.16A	1kglA-2wtzA: undetectable	1kglA-2wtzA: 10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UDU_B_CIAB2003_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	ALA A 353 ILE A 354 ILE A 297 PHE A 266 LEU A 265	None None None KCX A 262 ( 4.5A) KCX A 262 ( 4.4A)	1.03A	1uduB-2wtzA: undetectable	1uduB-2wtzA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_B_SAMB500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 11	VAL A 210 ALA A 204 ALA A 136 ASP A 76 PRO A 28	None	1.04A	2admB-2wtzA: undetectable	2admB-2wtzA: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2B7Z_B_MK1B200_1 (HIV-1 PROTEASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	GLY A 99 ALA A 100 ASP A 76 ALA A 117 VAL A 119	None	1.06A	2b7zA-2wtzA: undetectable	2b7zA-2wtzA: 10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JJP_A_KLNA413_1 (CYTOCHROME P450 113A1)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	HIS A 252 ALA A 227 LEU A 228 ALA A 225 THR A 196	None None None UAG A1498 ( 4.8A) UAG A1498 (-4.7A)	1.10A	2jjpA-2wtzA: undetectable	2jjpA-2wtzA: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_B_FFOB505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	GLY A 376 VAL A 497 PRO A 340 GLY A 320 ARG A 373	None	0.96A	2vmyA-2wtzA: undetectable	2vmyA-2wtzA: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_A_SAMA1248_0 (NON-STRUCTURAL PROTEIN 5)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	GLY A 64 GLY A 75 THR A 63 VAL A 138 THR A 137	None	1.07A	2wa2A-2wtzA: undetectable	2wa2A-2wtzA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z0Y_A_SAMA300_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 9	ALA A 501 GLY A 504 LEU A 499 ILE A 381 LEU A 390	None	0.98A	2z0yA-2wtzA: 3.9	2z0yA-2wtzA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FW1_A_STIA233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 10	GLY A 156 TYR A 343 ASN A 344 GLU A 220 ILE A 151	None	1.37A	3fw1A-2wtzA: 3.1	3fw1A-2wtzA: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KKZ_B_SAMB302_0 (UNCHARACTERIZED PROTEIN Q5LES9)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	GLY A 140 GLY A 233 GLY A 133 LEU A 131 GLU A 144	None	0.93A	3kkzB-2wtzA: 2.5	3kkzB-2wtzA: 17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 9	GLY A 156 TYR A 343 ASN A 344 GLU A 220 ILE A 151	None	1.31A	3owxA-2wtzA: 3.1	3owxA-2wtzA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_B_XRAB233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 11	GLY A 156 TYR A 343 ASN A 344 GLU A 220 ILE A 151	None	1.41A	3owxA-2wtzA: 3.1 3owxB-2wtzA: 2.8	3owxA-2wtzA: 17.72 3owxB-2wtzA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_A_ACTA503_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	3 / 3	ARG A 521 GLU A 506 THR A 507	None	0.90A	3v4tA-2wtzA: undetectable	3v4tA-2wtzA: 25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_A_UEGA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 11	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.29A	4c5lA-2wtzA: 6.8	4c5lA-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_B_PXLB300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 9	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.31A	4c5lB-2wtzA: 2.3	4c5lB-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_C_UEGC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 10	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.26A	4c5lC-2wtzA: 2.3	4c5lC-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5L_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 10	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.26A	4c5lD-2wtzA: 4.6	4c5lD-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_B_PXLB300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 10	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.29A	4c5nB-2wtzA: 3.2	4c5nB-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_D_UEGD300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 10	GLY A 99 ASP A 76 GLY A 75 VAL A 72 VAL A 119	None	1.26A	4c5nD-2wtzA: 3.9	4c5nD-2wtzA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DO3_A_0LAA602_1 (FATTY-ACID AMIDE HYDROLASE 1)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 5	LEU A 146 LEU A 206 MET A 219 THR A 234	None	1.42A	4do3A-2wtzA: undetectable	4do3A-2wtzA: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7B_C_ACTC513_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	3 / 3	TYR A 393 HIS A 505 ARG A 377	None	1.14A	4e7bC-2wtzA: undetectable	4e7bC-2wtzA: 25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FUB_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	3 / 3	TYR A 162 ARG A 377 HIS A 505	None	1.01A	4fubA-2wtzA: undetectable	4fubA-2wtzA: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 6	THR A 195 GLU A 220 THR A 196 HIS A 252	UAG A1498 (-3.1A) None UAG A1498 (-4.7A) None	1.01A	4pgfA-2wtzA: 3.1	4pgfA-2wtzA: 23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNV_D_QI9D602_0 (CYTOCHROME P450 2D6)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 7	PHE A 236 LEU A 272 SER A 143 VAL A 221	None	0.98A	4wnvD-2wtzA: undetectable	4wnvD-2wtzA: 23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_P_BEZP801_1 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 6	PHE A 418 ALA A 420 HIS A 395 MET A 432	None	1.28A	5dzkB-2wtzA: undetectable 5dzkP-2wtzA: undetectable	5dzkB-2wtzA: 17.49 5dzkP-2wtzA: 7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_U_BEZU801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 6	PHE A 418 ALA A 420 HIS A 395 MET A 432	None	1.28A	5dzkg-2wtzA: 1.5 5dzku-2wtzA: undetectable	5dzkg-2wtzA: 17.49 5dzku-2wtzA: 7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E3I_B_HISB502_0 (HISTIDINE--TRNA LIGASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 11	THR A 158 ARG A 521 TYR A 162 GLY A 182 GLY A 179	None	1.32A	5e3iB-2wtzA: 3.0	5e3iB-2wtzA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	5 / 12	VAL A 164 LEU A 168 ALA A 175 ILE A 149 LEU A 202	None	1.09A	5hbsA-2wtzA: undetectable	5hbsA-2wtzA: 12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HPU_A_IPHA101_0 (INSULIN, CHAIN A INSULIN, CHAIN B)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 4	CYH A 348 LEU A 369 LEU A 352 ALA A 365	None	1.02A	5hpuA-2wtzA: undetectable 5hpuB-2wtzA: undetectable	5hpuA-2wtzA: 3.16 5hpuB-2wtzA: 4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJE_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 6	LEU A 228 ILE A 178 THR A 196 MET A 219	None None UAG A1498 (-4.7A) None	1.20A	5ljeA-2wtzA: undetectable	5ljeA-2wtzA: 10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UXC_A_ZITA306_1 (PREDICTED AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 7	ARG A 235 PHE A 236 LEU A 265 SER A 222	None None KCX A 262 ( 4.4A) UAG A1498 (-2.6A)	1.16A	5uxcA-2wtzA: undetectable	5uxcA-2wtzA: 24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WM2_A_ACTA605_0 (SALICYLATE-AMP LIGASE)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	3 / 3	THR A 180 THR A 158 ARG A 377	UAG A1498 ( 4.6A) None None	1.01A	5wm2A-2wtzA: 2.2	5wm2A-2wtzA: 27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CK2_C_IPHC101_0 (INSULIN A CHAIN INSULIN B CHAIN)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 4	ILE A 337 LEU A 352 HIS A 334 ALA A 325	None	0.97A	6ck2C-2wtzA: undetectable 6ck2D-2wtzA: undetectable	6ck2C-2wtzA: 3.16 6ck2D-2wtzA: 5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DYO_A_LDPA901_0 (EBONY)	2wtz	UDP-N-ACETYLMURAMOYL -L-ALANYL-D-GLUTAMAT E--2,6-DIAMINOPIMELA TE LIGASE (Mycobacterium tuberculosis)	4 / 5	VAL A 231 LEU A 226 HIS A 252 THR A 152	None None None KCX A 262 ( 3.6A)	1.32A	6dyoA-2wtzA: undetectable	6dyoA-2wtzA: 9.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CBR_B_REAB200_1","CELLULAR RETINOIC ACID BINDING PROTEIN TYPE I","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"ALA A 102;ALA A 100;PRO A  74;VAL A  62;ARG A  60","None","1.28A","1cbrB-2wtzA:undetectable","1cbrB-2wtzA:13.27"],["1FBM_B_RTLB951_3","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"LEU A 414;VAL A 497;LEU A 390;GLN A 380","None","0.80A","1fbmE-2wtzA:undetectable","1fbmE-2wtzA:9.06"],["1KGL_A_RTLA175_1","CELLULAR RETINOL-BINDING PROTEIN TYPE I","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"LEU A 228;ILE A 178;THR A 196;MET A 219","None;None;UAG A1498 (-4.7A);None","1.16A","1kglA-2wtzA:undetectable","1kglA-2wtzA:10.76"],["1UDU_B_CIAB2003_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"ALA A 353;ILE A 354;ILE A 297;PHE A 266;LEU A 265","None;None;None;KCX A 262 ( 4.5A);KCX A 262 ( 4.4A)","1.03A","1uduB-2wtzA:undetectable","1uduB-2wtzA:19.81"],["2ADM_B_SAMB500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"VAL A 210;ALA A 204;ALA A 136;ASP A  76;PRO A  28","None","1.04A","2admB-2wtzA:undetectable","2admB-2wtzA:22.78"],["2B7Z_B_MK1B200_1","HIV-1 PROTEASE;HIV-1 PROTEASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ALA A 100;ASP A  76;ALA A 117;VAL A 119","None","1.06A","2b7zA-2wtzA:undetectable","2b7zA-2wtzA:10.89"],["2JJP_A_KLNA413_1","CYTOCHROME P450 113A1","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"HIS A 252;ALA A 227;LEU A 228;ALA A 225;THR A 196","None;None;None;UAG A1498 ( 4.8A);UAG A1498 (-4.7A)","1.10A","2jjpA-2wtzA:undetectable","2jjpA-2wtzA:24.18"],["2VMY_B_FFOB505_0","SERINE HYDROXYMETHYLTRANSFERASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A 376;VAL A 497;PRO A 340;GLY A 320;ARG A 373","None","0.96A","2vmyA-2wtzA:undetectable","2vmyA-2wtzA:23.53"],["2WA2_A_SAMA1248_0","NON-STRUCTURAL PROTEIN 5","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  64;GLY A  75;THR A  63;VAL A 138;THR A 137","None","1.07A","2wa2A-2wtzA:undetectable","2wa2A-2wtzA:20.87"],["2Z0Y_A_SAMA300_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA0657","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"ALA A 501;GLY A 504;LEU A 499;ILE A 381;LEU A 390","None","0.98A","2z0yA-2wtzA:3.9","2z0yA-2wtzA:22.08"],["3FW1_A_STIA233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A 156;TYR A 343;ASN A 344;GLU A 220;ILE A 151","None","1.37A","3fw1A-2wtzA:3.1","3fw1A-2wtzA:17.54"],["3KKZ_B_SAMB302_0","UNCHARACTERIZED PROTEIN Q5LES9","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A 140;GLY A 233;GLY A 133;LEU A 131;GLU A 144","None","0.93A","3kkzB-2wtzA:2.5","3kkzB-2wtzA:17.94"],["3OWX_A_XRAA233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A 156;TYR A 343;ASN A 344;GLU A 220;ILE A 151","None","1.31A","3owxA-2wtzA:3.1","3owxA-2wtzA:17.72"],["3OWX_B_XRAB233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A 156;TYR A 343;ASN A 344;GLU A 220;ILE A 151","None","1.41A","3owxA-2wtzA:3.1;3owxB-2wtzA:2.8","3owxA-2wtzA:17.72;3owxB-2wtzA:17.72"],["3V4T_A_ACTA503_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",3,"ARG A 521;GLU A 506;THR A 507","None","0.90A","3v4tA-2wtzA:undetectable","3v4tA-2wtzA:25.30"],["4C5L_A_UEGA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.29A","4c5lA-2wtzA:6.8","4c5lA-2wtzA:20.04"],["4C5L_B_PXLB300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.31A","4c5lB-2wtzA:2.3","4c5lB-2wtzA:20.04"],["4C5L_C_UEGC300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.26A","4c5lC-2wtzA:2.3","4c5lC-2wtzA:20.04"],["4C5L_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.26A","4c5lD-2wtzA:4.6","4c5lD-2wtzA:20.04"],["4C5N_B_PXLB300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.29A","4c5nB-2wtzA:3.2","4c5nB-2wtzA:20.04"],["4C5N_D_UEGD300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"GLY A  99;ASP A  76;GLY A  75;VAL A  72;VAL A 119","None","1.26A","4c5nD-2wtzA:3.9","4c5nD-2wtzA:20.04"],["4DO3_A_0LAA602_1","FATTY-ACID AMIDE HYDROLASE 1","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"LEU A 146;LEU A 206;MET A 219;THR A 234","None","1.42A","4do3A-2wtzA:undetectable","4do3A-2wtzA:22.66"],["4E7B_C_ACTC513_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",3,"TYR A 393;HIS A 505;ARG A 377","None","1.14A","4e7bC-2wtzA:undetectable","4e7bC-2wtzA:25.30"],["4FUB_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",3,"TYR A 162;ARG A 377;HIS A 505","None","1.01A","4fubA-2wtzA:undetectable","4fubA-2wtzA:17.67"],["4PGF_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"THR A 195;GLU A 220;THR A 196;HIS A 252","UAG A1498 (-3.1A);None;UAG A1498 (-4.7A);None","1.01A","4pgfA-2wtzA:3.1","4pgfA-2wtzA:23.35"],["4WNV_D_QI9D602_0","CYTOCHROME P450 2D6","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"PHE A 236;LEU A 272;SER A 143;VAL A 221","None","0.98A","4wnvD-2wtzA:undetectable","4wnvD-2wtzA:23.94"],["5DZK_P_BEZP801_1","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"PHE A 418;ALA A 420;HIS A 395;MET A 432","None","1.28A","5dzkB-2wtzA:undetectable;5dzkP-2wtzA:undetectable","5dzkB-2wtzA:17.49;5dzkP-2wtzA:7.69"],["5DZK_U_BEZU801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"PHE A 418;ALA A 420;HIS A 395;MET A 432","None","1.28A","5dzkg-2wtzA:1.5;5dzku-2wtzA:undetectable","5dzkg-2wtzA:17.49;5dzku-2wtzA:7.69"],["5E3I_B_HISB502_0","HISTIDINE--TRNA LIGASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"THR A 158;ARG A 521;TYR A 162;GLY A 182;GLY A 179","None","1.32A","5e3iB-2wtzA:3.0","5e3iB-2wtzA:23.17"],["5HBS_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",5,"VAL A 164;LEU A 168;ALA A 175;ILE A 149;LEU A 202","None","1.09A","5hbsA-2wtzA:undetectable","5hbsA-2wtzA:12.16"],["5HPU_A_IPHA101_0","INSULIN, CHAIN A;INSULIN, CHAIN B","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"CYH A 348;LEU A 369;LEU A 352;ALA A 365","None","1.02A","5hpuA-2wtzA:undetectable;5hpuB-2wtzA:undetectable","5hpuA-2wtzA:3.16;5hpuB-2wtzA:4.93"],["5LJE_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"LEU A 228;ILE A 178;THR A 196;MET A 219","None;None;UAG A1498 (-4.7A);None","1.20A","5ljeA-2wtzA:undetectable","5ljeA-2wtzA:10.56"],["5UXC_A_ZITA306_1","PREDICTED AMINOGLYCOSIDE PHOSPHOTRANSFERASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"ARG A 235;PHE A 236;LEU A 265;SER A 222","None;None;KCX A 262 ( 4.4A);UAG A1498 (-2.6A)","1.16A","5uxcA-2wtzA:undetectable","5uxcA-2wtzA:24.21"],["5WM2_A_ACTA605_0","SALICYLATE-AMP LIGASE","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",3,"THR A 180;THR A 158;ARG A 377","UAG A1498 ( 4.6A);None;None","1.01A","5wm2A-2wtzA:2.2","5wm2A-2wtzA:27.20"],["6CK2_C_IPHC101_0","INSULIN A CHAIN;INSULIN B CHAIN","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"ILE A 337;LEU A 352;HIS A 334;ALA A 325","None","0.97A","6ck2C-2wtzA:undetectable;6ck2D-2wtzA:undetectable","6ck2C-2wtzA:3.16;6ck2D-2wtzA:5.16"],["6DYO_A_LDPA901_0","EBONY","2wtz","UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE","Mycobacterium tuberculosis",4,"VAL A 231;LEU A 226;HIS A 252;THR A 152","None;None;None;KCX A 262 ( 3.6A)","1.32A","6dyoA-2wtzA:undetectable","6dyoA-2wtzA:9.44"]]